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One in seven people experience migraine headaches while others suffer with even more debilitating cluster headaches. The causes of these headaches are not fully understood and current treatments provide only partial relief. In this episode pharmacologist Antoinette van den Brink and neurologist Rolf Fronczek describe the clinical features of these headaches, the current understanding of their causes, and hormonal and environmental factors that can trigger the headaches. Drugs that inhibit the peptide CGRP and electrical stimulation of the occipital nerve are among treatments shown to be effective in reducing headache intensity or duration.
LINKS
University webpages:
https://www.erasmusmc.nl/en/research/researchers/maassen-van-den-brink-antoinette
https://hoofdpijnonderzoek.nl/en/team/dr-rolf-fronczek/
Migraine headache articles
https://journals.sagepub.com/doi/epub/10.1177/03331024241238153
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10863119/pdf/10194_2024_Article_1724.pdf
Cluster headache articles
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018790/pdf/40263_2019_Article_696.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10755111/pdf/main.pdf
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