Best Especially Big Data Podcasts (2025)

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How OpenAI Builds for 800 Million Weekly Users: Model Specialization and Fine-Tuning 53:24

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3d ago53:24

53:24

In this episode, a16z GP Martin Casado sits down with Sherwin Wu, Head of Engineering for the OpenAI Platform, to break down how OpenAI organizes its platform across models, pricing, and infrastructure, and how it is shifting from a single general-purpose model to a portfolio of specialized systems, custom fine-tuning options, and node-based agent …

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Ben Horowitz: Why Open Source AI Will Determine America's Future 46:50

4d ago46:50

46:50

Ben Horowitz reveals why the US already lost the AI culture war to China—and it wasn't the technology that failed. While Biden's team played Manhattan Project with closed models, Chinese developers quietly captured the open-source heartbeat of global AI through DeepSeek, now running inside every major US company and university lab. The kicker: Goog…

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Data Centers Are a Climate Enemy w/ Ketan Joshi 58:30

4d ago58:30

58:30

Paris Marx is joined by Ketan Joshi to discuss how hyperscale data centers are fueling the consumption of more oil and gas, what that means for climate targets, and the insidious relationship between the tech and fossil fuel industries. Ketan Joshi is a climate writer and data analyst based in Oslo working with climate and environmental groups. Tec…

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The Secret Marketing Strategy That Built a16z: From Zero to Legendary VC Firm 59:55

5d ago59:55

59:55

Marc Andreessen and Ben Horowitz sit down with Margit Wennmachers—the woman who turned two unknown entrepreneurs with $300 million and zero investing track record into the most talked-about firm in venture capital. She unpacks how they weaponized transparency in an industry built on secrecy, why Fortune's cover story triggered a cartel meltdown, an…

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How Marc Andreessen Actually Uses AI 34:02

6d ago34:02

34:02

Half a billion people can access the world’s best AI on their phone. So why are most using it to write emails while only some are using it to build empires? In this conversation with Mark Halperin from Next Up, Marc Andreessen reveals why small bakeries are beating Fortune 500 companies at AI adoption, how to turn ChatGPT into your personal board o…

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The 2045 Superintelligence Timeline: Epoch AI’s Data-Driven Forecast 1:00:10

7d ago1:00:10

1:00:10

Epoch AI researchers reveal why Anthropic might beat everyone to the first gigawatt datacenter, why AI could solve the Riemann hypothesis in 5 years, and what 30% GDP growth actually looks like. They explain why "energy bottlenecks" are just companies complaining about paying 2x for power instead of getting it cheap, why 10% of current jobs will va…

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Robinhood CEO: Making Everyone An Owner 1:05:02

10d ago1:05:02

1:05:02

Vlad Tenev built Robinhood by breaking every rule Wall Street wrote: zero commissions when competitors charged $10, mobile-first when "serious" investors demanded desktop, a brand that made finance feel like rebellion instead of a club you'd never join. By 2021 they'd forced every major brokerage to slash fees and attracted millions who'd never own…

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Can Community Banks Survive the Next SVB? | ModernFi CEO Paolo Bertolotti and Former Comptroller Gene Ludwig 43:42

11d ago43:42

43:42

The former bank regulator who invented deposit networks just revealed why SVB's collapse was inevitable—and why the solution that could have saved them is finally being rebuilt. Gene Ludwig ran the OCC during the Clinton administration, created a half-trillion-dollar market solving a problem his Aunt Betty faced riding buses between banks, then wat…

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Peter Thiel is the Real Antichrist w/ Gil Duran 1:01:04

11d ago1:01:04

1:01:04

Paris Marx is joined by Gil Duran to discuss how Peter Thiel’s bizarre obsession with the antichrist is really a desperate and embarrassing attempt to divert attention from his own misdeeds. Gil Duran writes The Nerd Reich and is working on his first book, The Nerd Reich: Silicon Valley Fascism and the War on Global Democracy. Tech Won’t Save Us of…

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Ben Horowitz & Marc Andreessen: Why Silicon Valley Turned Against Defense (And How We’re Fixing It) 1:16:13

12d ago1:16:13

1:16:13

Palmer Luckey got fired from Meta for backing the wrong candidate—now he's the hero saving American defense, and that shift tells you everything about how fast the ground moved beneath Silicon Valley's feet. For decades, tech and defense were allies, then came 15 years of hostility so visceral that Google employees revolted over a Pentagon AI contr…

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Emmett Shear on Building AI That Actually Cares: Beyond Control and Steering 1:10:36

14d ago1:10:36

1:10:36

Emmett Shear, founder of Twitch and former OpenAI interim CEO, challenges the fundamental assumptions driving AGI development. In this conversation with Erik Torenberg and Séb Krier, Shear argues that the entire "control and steering" paradigm for AI alignment is fatally flawed. Instead, he proposes "organic alignment" - teaching AI systems to genu…

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Can America Win The AI Biotech Race Against China? | Lada Nuzhna & Elliot Hershberg 1:02:23

17d ago1:02:23

1:02:23

Two venture capitalists dissect why biotech burns billions while China runs trials in weeks—and why the next Genentech won't look anything like the last one. Elliot Hershberg reveals the "three horsemen" strangling drug development as costs explode to $2.5 billion per approval, while Lada Nuzhna exposes how investigator-initiated trials in Shanghai…

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The Frontier of Spatial Intelligence with Fei-Fei Li 44:11

18d ago44:11

44:11

Fei-Fei Li and Justin Johnson are pioneers in AI. While the world has only recently witnessed a surge in consumer AI, they have long been laying the groundwork for the innovations transforming industries today. With the recent launch of Marble, the first product from their company World Labs, we are revisiting this conversation to explore the ideas…

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Saudi Arabia is Using Games to Improve Its Image w/ Nathan Grayson 56:02

18d ago56:02

56:02

Paris Marx is joined by Nathan Grayson to discuss how Saudi Arabia is buying its way into the sports, comedy, and video game industries in order to broaden its investment portfolio and launder its international reputation. Nathan Grayson is a cofounder of Aftermath and the author of Stream Big: The Triumphs and Turmoils of Twitch and the Stars Behi…

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Rocket Companies CEO: Here’s How to Fix the Housing Crisis 55:55

19d ago55:55

55:55

The Empire State Building took 110 days to build—today, changing a window would take two years. Alex Rampell (a16z) and Varun Krishna (Rocket CEO) expose how asset inflation turned housing from the American Dream into a wealth transfer machine where the median homebuyer age jumped from 30 to 38 in just fourteen years. While Silicon Valley burns bil…

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Grant Lee: Building Gamma’s AI Presentation Company to 100 Million Users 53:17

20d ago53:17

53:17

Grant Lee was told Gamma was "the worst idea ever heard" by an investor who hung up mid-Zoom—yet he built it to 100 million users and $100M ARR without spending a dollar on advertising. While competitors hired aggressively, Grant's team of seven refused to grow, dedicating 25% of their tiny team to design and personally onboarding every influencer …

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Michael Truell: How Cursor Builds at the Speed of AI 27:30

20d ago27:30

27:30

When four MIT grads decided to build a code editor while everyone else was building AI agents, they created the fastest-growing developer tool ever built. Cursor CEO Michael Truell joins a16z’s Martin Casado to discuss the deliberate constraints that led to breakthroughs: why they rejected the "democratization" narrative to focus on power users, ho…

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a16z's State of Crypto: The $4 Trillion Milestone and What's Next' 1:38:31

22d ago1:38:31

1:38:31

The regulatory environment has completely inverted. Stablecoins are now a top 20 holder of US treasuries. Every major bank wants in. In a16z Crypto's 2025 State of Crypto report, Daren Matsuoka (Head of Data) and Eddy Lazzarin (CTO) reveal how crypto hit $4 trillion market cap while fundamentally reshaping how institutions think about payments, wit…

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Amjad Masad & Adam D’Angelo: How Far Are We From AGI? 1:02:44

24d ago1:02:44

1:02:44

Adam D’Angelo (Quora/Poe) thinks we're 5 years from automating remote work. Amjad Masad (Replit) thinks we're brute-forcing intelligence without understanding it. In this conversation, two technical founders who are building the AI future disagree on almost everything: whether LLMs are hitting limits, if we're anywhere close to AGI, and what happen…

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Mark Zuckerberg & Priscilla Chan: How AI Will Cure All Disease 45:21

24d ago45:21

45:21

Priscilla Chan and Mark Zuckerberg join a16z’s Ben Horowitz, Erik Torenberg, and Vineeta Agarwala to share how the Chan Zuckerberg Initiative is building the computational tools that will accelerate the cure, prevention, and management of all disease by century's end. They explain why basic science needs $100 million-scale projects that traditional…

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Why We Need a War on Cars w/ Doug Gordon and Sarah Goodyear 1:02:46

25d ago1:02:46

1:02:46

Paris Marx is joined by Doug Gordon and Sarah Goodyear to discuss the many ways cars have negatively affected society, how tech companies seek to entrench those problems, and what can really be done to improve mobility in our communities. Doug Gordon is a TV producer and writer. Sarah Goodyear is a journalist and author. They are the co-hosts of Th…

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Seeing The Future from AI Companions to Personal Software 50:20

26d ago50:20

50:20

Eugenia Kuyda, CEO of Wabi and AI pioneer behind Replika, joins Erik, Anish, and Justine to reveal how personal software will transform from a developer monopoly to a creative medium for all. She exposes why command-line AI interfaces are the new MS-DOS, explains how mini-apps will become as shareable as TikToks, and details her decade-long journey…

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ElevenLabs CEO: Why Voice is the Next AI Interface 31:14

26d ago31:14

31:14

ElevenLabs CEO and co‑founder Mati Staniszewski joins Jennifer Li to explain how the team ships research‑grade AI at lightning speed—from text‑to‑speech and fully licensed AI music to real‑time voice agents—and why voice is the next interface for human‑computer interaction. He shares the small, autonomous team model, global hiring approach, and how…

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David Sacks: AI, Crypto, China, Dems, and SF 1:16:57

28d ago1:16:57

1:16:57

David Sacks, White House AI and Crypto Czar, joins Marc, Ben, and Erik to explore what's really happening inside the Trump administration's AI and crypto strategy. They expose the regulatory capture playbook being pushed by certain AI companies, explain why open source is America's secret weapon, and detail the infrastructure crisis that could dete…

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Why Speed, Not Size, Will Define the Next War 39:25

29d ago39:25

39:25

As global tensions rise, AI and autonomy are transforming how nations prepare for conflict. In this episode, Horacio Rozanski, CEO of Booz Allen Hamilton and Gary Shield, CEO of Shield AI join Erik Torenberg to discuss how technology, speed, and public–private partnerships are reshaping America’s defense strategy. They cover lessons from Ukraine an…

1
Beyond Chatbots: Marc Andreessen and Ben Horowitz on AI's Future 38:11

1M ago38:11

38:11

In this closing keynote from a16z’s Runtime conference, General Partner Erik Torenberg speaks with our firm’s cofounders, Marc Andreessen and Ben Horowitz on highlights from throughout the conference, the current state of LLM capabilities, and why despite huge capex, AI is not a bubble. Resources: Follow Marc on X: https://x.com/pmarca Follow Ben o…

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"Is there an AI bubble?” Gavin Baker and David George 31:50

1M ago31:50

31:50

In this conversation from a16z’s Runtime conference, Gavin Baker, Managing Partner and CIO of Atreides Management, joins David George, General Partner at a16z, to unpack the macro view of AI: the trillion-dollar data center buildout, the new economics of GPUs, and what this boom means for investors, founders, and the global economy. Resources: Foll…

1
We Need to Cut Our Dependence on US Tech. Here’s How to Start. 46:07

1M ago46:07

46:07

Paris Marx celebrates the 300th episode of Tech Won’t Save Us by sharing his reasons to push for digital sovereignty and get off US tech. On top of explaining how that dependence gives the US governments and its tech companies power over us, Paris also provides tips of alternative services to consider migrating to. Tech Won’t Save Us offers a criti…

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Building the Real-World Infrastructure for AI, with Google, Cisco & a16z 32:44

1M ago32:44

32:44

AI isn’t just changing software, it’s causing the biggest buildout of physical infrastructure in modern history. In this episode, Raghu Raghuram (a16z) speaks with Amin Vahdat, VP and GM of AI and Infrastructure at Google, and Jeetu Patel, President and Chief Product Officer at Cisco, about the unprecedented scale of what’s being built — from chips…

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Google DeepMind Developers: How Nano Banana Was Made 54:19

1M ago54:19

54:19

Google DeepMind’s new image model Nano Banana took the internet by storm. In this episode, we sit down with Principal Scientist Oliver Wang and Group Product Manager Nicole Brichtova to discuss how Nano Banana was created, why it’s so viral, and the future of image and video editing. Resources: Follow Oliver on X: https://x.com/oliver_wang2 Follow …

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Raghu Raghuram: AI, Robotics, and the Rebirth of Infrastructure 30:12

1M ago30:12

30:12

From Netscape to VMware, Raghu Raghuram has been at the center of nearly every major inflection point in enterprise technology. In this episode, Raghu joins Ben Horowitz, Martin Casado and David George to reflect on the early internet wars with Microsoft, how Netscape’s browser battles shaped a generation of founders, and the inside story of one of…

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Marc Andreessen: How Movies Explain America 1:15:30

1M ago1:15:30

1:15:30

In this episode of Monitoring the Situation, Marc Andreessen, Katherine Boyle, and Erik Torenberg dive into the movies that best explain America, from Once Upon a Time in Hollywood to Tropic Thunder to Fight Club. They explore how Tarantino’s revisionist masterpiece reimagines 1969 and the end of America’s cultural innocence, why Tropic Thunder was…

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Marc Andreessen and Amjad Masad: English As the New Programming Language 1:11:38

1M ago1:11:38

1:11:38

Amjad Masad, founder and CEO of Replit, joins a16z’s Marc Andreessen and Erik Torenberg to discuss the new world of AI agents, the future of programming, and how software itself is beginning to build software. They trace the history of computing to the rise of AI agents that can now plan, reason, and code for hours without breaking, and explore how…

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Silicon Valley Doesn’t Know What Makes a Good City w/ Joanne McNeil 55:08

1M ago55:08

55:08

Paris Marx is joined by Joanne McNeil to discuss the proliferation of delivery bots and robotaxis and how they recycle disproven claims about how technology will improve transportation. Joanne McNeil is a freelance writer and the author of Wrong Way and Lurking: How a Person Became a User. Tech Won’t Save Us offers a critical perspective on tech, i…

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Why Creativity Will Matter More Than Code 1:25:15

1M ago1:25:15

1:25:15

In this episode, a16z's Anish Acharya joins Kevin Rose for an in-depth, fast-paced conversation on the rebirth of consumer technology, and how AI is reshaping what it means to build, invest, and create. They talk about why AI has reignited the consumer renaissance, what it means to build “weird and working” products, and how the next wave of apps w…

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How Kong Was Born: APIs, Hustle, and the Future of AI Infrastructure 37:57

1M ago37:57

37:57

Augusto Marietti, CEO and cofounder of Kong, has one of the most remarkable founder stories in Silicon Valley history. In this conversation with Martin Casado, Aghi shares how he went from a garage in Milan to building one of the world’s leading API infrastructure companies, surviving years of rejection, living in the U.S. on $1,000 a month, and ra…

1
Reid Hoffman on AI, Consciousness, and the Future of Humanity 53:00

1M ago53:00

53:00

Reid Hoffman has been at the center of every major tech shift, from co-founding LinkedIn and helping build PayPal to investing early in OpenAI. In this conversation, he looks ahead to the next transformation: how artificial intelligence will reshape work, science, and what it means to be human. In this episode, Reid joins Erik Torenberg and Alex Ra…

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Marc Andreessen on the State of Film and Hollywood 1:07:46

1M ago1:07:46

1:07:46

Hollywood is going through a major cultural and creative reset, and Marc Andreessen thinks it’s long overdue. In this episode of Monitoring the Situation, Marc joins Erik Torenberg and Katherine Boyle to dissect the past decade of filmmaking, from the rise of “the message” in every movie to the return of genuine comedy and art. They cover the post-…

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Keith Rabois: Israel, OpenAI, Opendoor, and DOGE 49:08

2M ago49:08

49:08

From politics to technology to real estate, Keith Rabois has bold predictions for America’s next decade. In this conversation with Erik Torenberg, Keith breaks down why he believes the U.S. is entering a new economic expansion driven by AI, productivity, and sovereign technology. They discuss how AI could lift GDP growth to 5%, why sovereign AI pro…

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Smart Glasses Are Ushering In An Anti-Social World w/ Chris Gilliard 55:18

2M ago55:18

55:18

Paris Marx is joined by Chris Gilliard to discuss how tech CEOs are pushing a new generation of AI-powered smart glasses by promising they’ll be stylish and indispensable to workers in a desperate attempt to convince us we should want their luxury surveillance gadgets. Chris Gilliard is the co-director of the Critical Internet Studies Institute and…

1
Ben Horowitz and Ali Ghodsi: How to Run a Billion-Dollar Business 1:04:36

2M ago1:04:36

1:04:36

By Ali Ghodsi, Erik Torenberg, Ben Horowitz

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Is AI Slowing Down? Nathan Labenz Says We're Asking the Wrong Question 1:31:02

2M ago1:31:02

1:31:02

Nathan Labenz is one of the clearest voices analyzing where AI is headed, pairing sharp technical analysis with his years of work on The Cognitive Revolution. In this episode, Nathan joins a16z’s Erik Torenberg to ask a pressing question: is AI progress actually slowing down, or are we just getting used to the breakthroughs? They discuss the debate…

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Columbia CS Professor: Why LLMs Can’t Discover New Science 50:54

2M ago50:54

50:54

From GPT-1 to GPT-5, LLMs have made tremendous progress in modeling human language. But can they go beyond that to make new discoveries and move the needle on scientific progress? We sat down with distinguished Columbia CS professor Vishal Misra to discuss this, plus why chain-of-thought reasoning works so well, what real AGI would look like, and w…

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Monitoring the Situation #3: Who Is Nick Land? 52:44

2M ago52:44

52:44

Zach Dell is founder and CEO of Base Power, an energy tech company that builds affordable, reliable power via home batteries. In this episode of Monitoring the Situation, a16z General Partners Erik Torenberg, Katherine Boyle, and Erin Price-Wright sit down with Zach to discuss the current state of home power generation, what’s misunderstood about t…

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The Gilded Rage of Tech Billionaires w/ Jacob Silverman 55:01

2M ago55:01

55:01

Paris Marx is joined by Jacob Silverman to discuss Jacob’s new book Gilded Rage, which explores the radicalization of Silicon Valley leaders, who are exerting their growing influence to shape our society for the worse. Jacob Silverman is an independent journalist and the author of Gilded Rage: Elon Musk and the Radicalization of Silicon Valley. Tec…

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Sam Altman on Sora, Energy, and Building an AI Empire 48:25

2M ago48:25

48:25

Sam Altman has led OpenAI from its founding as a research nonprofit in 2015 to becoming the most valuable startup in the world ten years later. In this episode, a16z Cofounder Ben Horowitz and General Partner Erik Torenberg sit down with Sam to discuss the core thesis behind OpenAI’s disparate bets, why they released Sora, how they use models inter…

1
How to Build a Real Estate Marketplace - Kaz Nejatian, Opendoor CEO 55:44

2M ago55:44

55:44

By Kaz Nejatian, Alex Rampell

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Can the US Beat China’s Engineering State? 1:03:10

2M ago1:03:10

1:03:10

From high-speed rail to electric cars to batteries to AI, it’s clear that China can operate with incredible speed at massive scale. Can the US still compete? We sat down with Dan Wang, a Research Fellow at the Hoover Institution and the author of “Breakneck: China’s Quest to Engineer the Future” to discuss. Timecodes: 0:00 Introduction 1:36 Lawyers…

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Monitoring the Situation #2: Alana Newhouse 58:58

2M ago58:58

58:58

Two trends in media have been abundantly clear since 2020: legacy media is dying, and independent media is rising. a16z General Partners Erik Torenberg and Katherine Boyle sit down with Tablet founder and editor-in-chief Alana Newhouse to discuss the great media realignment, why real institutions will outlast the new “internet pirates", Alana’s dee…

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Software is Eating Labor 26:49

2M ago26:49

26:49

Software has fundamentally changed the way we record, store, and share information. Its next act is to fundamentally change the nature of our economy, capturing trillions of dollars of value in the process. In this talk from the 2025 a16z LP Summit, a16z General Partner Alex Rampell discusses the history of filing cabinets and databases, how SaaS p…