Best Geroscience Podcasts (2025)

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#36 How crypto is sparking a longevity frenzy 1:48:15

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3d ago1:48:15

1:48:15

Today we’re diving into one of the strangest and most ambitious ideas in longevity: using crypto trading to fund real-time lifespan experiments. Benji Leibowitz, founder of pump.science, joins us to explain how decentralized science works, why tokens can finance studies in worms, flies and mice, and what happens when a single post on X suddenly tur…

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#35 The Anti-Aging Uprising: Felix Werth’s Political Attack on Death Itself 1:24:36

24d ago1:24:36

1:24:36

Valuable time is being lost because there is not enough funding for science with real life-extending potential. No major political party is promising to address aging, even though aging harms and kills more people than anything else. Most people—and most leaders—still do not understand that aging is both a problem and something that can be solved t…

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Circadian Rhythm and Intermittent Fasting for Healthy Lifespan - LEE Tuh-Fuh and Ruby LEE Wang Zu-Ming Endowed Lecture 1:27:52

28d ago1:27:52

1:27:52

Circadian timing shapes how we sleep, feel, and function each day. Satchidananda Panda, Ph.D., Salk Institute, explains that keeping daily light, meals, movement, and sleep in step with the body’s internal clock supports alertness, metabolism, and recovery. Panda notes that evening light and late eating can make it harder to fall asleep and may wor…

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#34 Biomarkers of aging: How close are we, really? - A conversation with Sara Hägg 1:36:22

1M ago1:36:22

1:36:22

Sara Hägg, PhD is an associate professor at Karolinska Institutet, where she leads the Molecular Epidemiology of Aging Group. Her work focuses on human biomarkers of aging - especially biological age “clocks” built from epigenetic, proteomic, and metabolomic data - and on turning Nordic registry resources into clinically useful aging measures. In t…

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Mental Health and Resilience 42:37

1M ago42:37

42:37

Psychological resilience in later life examines how older adults adapt after adversity and cultivate everyday practices that sustain well-being and purpose.Elizabeth W. Twamley, Ph.D., introduces and guides a discussion on mental health and resilience among older adults. Ellen E. Lee, M.D., characterizes resilience as dynamic learning oriented towa…

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Cognitive Health and Resilience 44:16

2M ago44:16

44:16

Cognitive resilience grows from small, consistent habits that keep the brain adaptable. Fadel Zeidan, Ph.D., frames mindfulness as mental training that improves attention, processing, and the way people relate to pain. Erin E. Sundermann, Ph.D., underscores modifiable pathways to healthier aging, highlighting movement, social connection, hearing su…

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Translational Geroscience: Using Aging Research to Improve Resilience in Older Adults 48:00

2M ago48:00

48:00

Targeting the biology of aging offers a path to stronger resilience and longer health. John C. Newman, M.D., Ph.D., explains that aging arises from measurable cellular processes, often called hallmarks of aging, including changes involving mitochondria, stem cells, cellular senescence, inflammation, and protein quality control. Newman describes how…

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Physical Health and Resilience 49:42

2M ago49:42

49:42

Healthy aging starts with physical resilience, the body’s ability to withstand and recover from stress. Maile Young Karris, M.D., defines the concept and sets the stage for practical strategies that match real-world needs. Ryan J. Moran, M.D., M.P.H., recommends simple routines such as wall push ups, posture alignment, and chin tucks, and he links …

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#33 “Can death be the answer?" A conversation with philosopher Nicholas Agar 1:44:30

2M ago1:44:30

1:44:30

We are always excited about the next technological solution. But what if it does not come? Or what if it comes only for the few, or with terrible side-effects? And while we are waiting for the easy tech fix, are we neglecting what we can do now to better our lives? Many of our previous guests have been excited about the prospect of radically extend…

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The Science of Bouncing Back: How Resilience Changes Across the Lifespan 47:41

2M ago47:41

47:41

Heather E. Whitson, MD, MHS explores how resilience—the ability to recover and adapt after stress or illness—changes across the lifespan. She explains that bounce back slows with age and that people age at different rates, influenced by biology, lifestyle, and environment. Studies connect lower inflammation, stronger cellular health, and emotional …

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Navigating Grief: What the Science of Resilience Teaches about Adaptation to Loss 1:09:20

2M ago1:09:20

1:09:20

Danielle K. Glorioso, LCSW, explores the complex nature of grief, emphasizing that it is a lifelong, evolving response to loss rather than something to “get over.” She explains the differences between acute grief, integrated grief, and prolonged grief disorder, highlighting how factors like attachment, personal history, and circumstances of death c…

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#32 “Medical malpractice”: Matt Kaeberlein on biological age tests 1:50:07

2M ago1:50:07

1:50:07

One idea I’ve had lately is to put together a list of people to trust in geroscience and the longevity field more broadly. (And I might do it - keep an eye on reachlevity.com - and subscribe while you’re at it!) Matt Kaeberlein would not only make that list - he’d likely be right at the top. He’s rigorous, precise in his wording, and always puts in…

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# 31 He wants to save your pet with cryo - The Kai Micah Mills interview 2:08:54

3M ago2:08:54

2:08:54

When you give a child a pet, you also expose them to death—since most pets pass away long before their owners. But what if we could cryopreserve Buddy or Tiger, and bring them back from suspended animation once we have a cure for what ended their lives? Kai Micah Mills is a pioneering figure in radical life extension and biostasis. As the founder o…

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#30 Soon you'll take a drug designed by AI | Alex Zhavoronkov 2:13:52

3M ago2:13:52

2:13:52

As you may have heard, AI-designed medicines have crossed a historic line. In this episode, Alex Zhavoronkov - CEO of Insilico Medicine and founder of ARDD walks us through how Insilico’s rentosertib became the first AI-generated small molecule with peer-reviewed clinical efficacy, while arguing against AI hype and reminding us that biology still m…

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Intermittent Fasting: A Strategy To Prevent Cardiometabolic Diseases And Promote Healthy Aging 54:24

3M ago54:24

54:24

Michael J. Wilkinson, M.D., F.A.C.C., F.N.L.A., explores the science and clinical evidence behind intermittent fasting and its role in promoting cardiometabolic health. He explains how aligning eating patterns with the body’s natural circadian rhythms can improve weight, blood pressure, glucose regulation, and other risk factors, especially in indi…

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Alzheimer's Disease in Women: Why Sex Differences Matter 5:14

4M ago5:14

5:14

Sarah Banks, Ph.D. explores why Alzheimer's disease affects women differently than men, emphasizing distinct patterns in tau pathology, cognitive testing bias, and treatment response. She explains how women tend to show a rapid buildup of tau during early cognitive decline, which may contribute to their higher prevalence of Alzheimer's. Banks also …

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#29 The Mindset behind longevity & strength at 75 - Natasha Vita-More 1:55:48

4M ago1:55:48

1:55:48

Anyone who is interesed in emerging science and futurism will come across the name Natasha Vita-More; a suggestive name for a charismatic and important philosopher and artist envisioning human possibilities. She wrote the Transhuman Manifesto in 1983. But did you know that she has also made a scientific discovery with big implications for cryoprese…

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Stein Institute for Research on Aging 3:52

4M ago3:52

3:52

Anthony Molina, Ph.D. highlights research and resources from the Stein Institute for Research on Aging that support healthy aging, with a focus on women’s health. He describes the institute’s work in training scientists, conducting clinical trials, and promoting community engagement. Key resources include a geroscience lab for biomarker discovery, …

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Healthy Aging and Longevity in Women 16:30

5M ago16:30

16:30

Andrea Z. LaCroix, Ph.D. presents major public health trends affecting women across the lifespan, from rising maternal mortality and chronic disease risks linked to pregnancy complications to the ongoing need for improved menopause care. She highlights innovative research, including digital tools for menopause education, studies on cancer survivors…

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#28 These rats don't age - here's why | Prof. Rochelle Buffenstein 1:43:04

5M ago1:43:04

1:43:04

Even though it’s undeniably...aesthetic-challenged, the naked mole-rat is the envy of the longevity world. Its risk of death barely changes with time; it shrugs off cancer, stays fertile for decades and seems to skip every hallmark of aging that hobbles the rest of us. But why? What evolutionary forces gave a mouse-sized, subterranean rodent near-i…

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Can this 5-day diet rewind your biological age? - A conversation with Andrea Ghirardi 36:40

5M ago36:40

36:40

🎁 Our giveaway is live! 10 winners will receive FMD kits from Prolon. It’s free to enter – just follow the link below 👇 https://gleam.io/NaVa0/prolon-fasting-mimicking-diet-giveaway 🔬 Can food rejuvenate you from within? In this special episode of LEVITY, Peter talks with Andrea Ghirardi, CEO of L-Nutra Europe — the company behind Prolon, the fasti…

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#27 The mind-blowing science to bring you back from death - neuroscientist Ariel Zeleznikow‑Johnston 1:58:31

5M ago1:58:31

1:58:31

When is someone really dead? What does it mean to survive? Is mind-uploading really a possible future way of surviving? These are some of the questions we are discussing with Dr Ariel Zeleznikow-Johnston. Dr Ariel Zeleznikow‑Johnston is a neuroscientist and Research Fellow at Monash University in Melbourne, Australia, whose work delves into the neu…

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#26 Inside Shift Bioscience’s single-gene rejuvenation breakthrough — Exclusive with CEO Daniel Ives 1:59:27

6M ago1:59:27

1:59:27

Just about the hottest thing in longevity science right now is partial reprogramming - using Yamanaka factors to rewind the biological clock in our cells. Billion-dollar giants like Altos, Retro and New Limit are betting on it. But in this episode a far smaller player, Shift Bioscience, argues that the field may be looking in the wrong place. CEO D…

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#25 What exactly is so bad about death? 2:13:03

6M ago2:13:03

2:13:03

We think that death is bad, but why exactly is it bad? We cannot suffer when we do not exist, so why would it be bad? In this episode we have a long, deep conversation with Professor Travis Timmerman, whose philosophical work delves deeply into the nature and ethics of death. An Associate Professor at Seton Hall University, Professor Timmerman has …

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Telomere Health 2:01

6M ago2:01

2:01

In this excerpt, Dr. Natalie Marshall discusses the central importance of exercise to improve chromosomal and telomere health. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40683]By UCTV: UC San Francisco

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Mindfulness-Based Mental Training to Enhance Well-Being and Healthy Aging 53:48

7M ago53:48

53:48

Fadel Zeidan, Ph.D., discusses the science of mindfulness and how meditation can change the brain. He explains what happens in the brain during stress, how mindfulness helps us become more self-aware, and why it's important to pay attention on purpose. Zeidan shares easy ways to bring mindfulness into daily life, even in small moments. The video in…

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#24 Dr. Valter Longo - The BIG 2025 interview 1:56:47

7M ago1:56:47

1:56:47

There were two reasons why Dr. Valter Longo was featured so prominently in my longevity book Evigt Ung (2022). First, if you had to name a single scientific thread running through the history of longevity research, calorie restriction is hard to beat. And few have done more to modernize and translate that insight into real-world practice than Longo…

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Hip Fracture Outcomes 1:33

7M ago1:33

1:33

Dr. Terence Friedlander reviews the various patient outcomes after hip fracture surgery. Series: "Excerpts" [Health and Medicine] [Show ID: 40752]By UCTV: UC San Francisco

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What Does Muscle Do For Us? 4:08

7M ago4:08

4:08

The risk for many chronic diseases is directly linked to metabolic changes in the body and loss of muscle mass often associated with aging. In this excerpt, Dr. Natalie Marshall focuses on the role that muscles play in the body. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40685]…

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Why Osteoporosis is Bad 1:19

7M ago1:19

1:19

Dr. Terence Friedlander discusses common issues brought on by osteoporosis. Series: "Excerpts" [Health and Medicine] [Show ID: 40751]By UCTV: UC San Francisco

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#23 Hilarious, brilliant and deadly serious: José Cordeiro's quest to defeat death 1:57:19

7M ago1:57:19

1:57:19

This is our first — and probably our last — episode where the guest has brought with him an actual punch card and proceeds to explain why it is, in fact, caca (which is Spanish for 💩, by the way). Welcome to the wild world of José Cordeiro. Stick around and you might hear anecdotes about Robert Kennedy Jr. in Memphis 🎸, late-night karaoke sessions …

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#22 Aging will be cured within 20 years — here's why | Prof. Derya Unutmaz 1:52:58

7M ago1:52:58

1:52:58

Lately, there's been growing pushback against the idea that AI will transform geroscience in the short term. When Nobel laureate Demis Hassabis told 60 Minutes that AI could help cure every disease within 5–10 years, many in the longevity and biotech communities scoffed. Leading aging biologists called it wishful thinking - or outright fantasy. The…

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How To Slow Aging 3:03

8M ago3:03

3:03

How can you make choices today that could help you live longer and feel better? Gordon Saxe, M.D., Ph.D., explores the ways to slow the aging process and live a healthier life. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40601]By UCTV: UC San Diego

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Sarcopenia: What You Need To Know 8:45

8M ago8:45

8:45

The risk for many chronic diseases is directly linked to metabolic changes in the body and loss of muscle mass often associated with aging. In this program, Dr. Natalie Marshall focuses on sarcopenia, low muscle mass, and the importance of strength training and body composition to improve metabolic fitness. Series: "Osher WISE: Well-being and Integ…

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#21 A Physicist's Controversial Take on Why Age Reversal Will Never Work | Peter Fedichev 1:28:15

8M ago1:28:15

1:28:15

Peter Fedichev is a visionary scientist, biotech entrepreneur, and physicist at the forefront of longevity research. With a background in theoretical physics, he has seamlessly merged cutting-edge science with real-world applications, making groundbreaking contributions to the fields of aging, biotechnology, and artificial intelligence in healthcar…

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Oxidative Stress: What You Need To Know 5:50

8M ago5:50

5:50

The risk for many chronic diseases is directly linked to metabolic changes in the body. In this program, Dr. Natalie Marshall focuses on the role of antioxidants and how they work against oxidative stress in the body. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40682]…

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#20 Want a quick $2 million? Help this guy find a longevity city! | Laurence Ion 1:54:50

8M ago1:54:50

1:54:50

In this episode of LEVITY, we speak with Laurence Ion, a tech entrepreneur whose experience with a rare genetic disease led him to tackle one of humanity's greatest challenges: aging. Starting as a shy coder who 'couldn't talk to strangers,' Laurence has become a movement leader pioneering a bold new approach: creating specialized cities where exte…

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Genes Are Not Destiny: What You Eat Matters 8:35

9M ago8:35

8:35

How can you make choices today that could help you live longer and feel better? Gordon Saxe, M.D., Ph.D. explores lifestyle choices, including diet, that can prevent, or slow, chronic diseases and improve overall health. Series: "Stein Institute for Research on Aging" [Health and Medicine] [Show ID: 40600]…

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#19 What are the chances humanity will survive this century? | Anders Sandberg 2:09:50

9M ago2:09:50

2:09:50

We have another amazing guest for this episode: Anders Sandberg is a visionary philosopher, futurist, and transhumanist thinker whose work pushes the boundaries of human potential and the future of intelligence. As a senior research fellow at Oxford University’s Future of Humanity Institute until its closing in 2024 Sandberg explores everything fro…

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Decoding the Dark Side of the Human Genome: How Ancient Viruses Shape Aging 46:32

9M ago46:32

46:32

Michael J. Corley, Ph.D., explores groundbreaking research on aging, the role of ancient viruses in our DNA, and the impact of the gut microbiome on longevity. Corley discusses how stress, diet, and exercise influence our genetic health, highlighting the complex interplay between environmental factors and our biological systems. The conversation al…

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#18 Aubrey de Grey | The Big 2025 Interview 1:55:13

9M ago1:55:13

1:55:13

In this in-depth conversation, Dr. Aubrey de Grey discusses his Robust Mouse Rejuvenation (RMR) studies at the LEV Foundation and why he believes we're close to achieving the crucial RMR milestone within just three years - a breakthrough that could transform aging research forever. You'll also hear about: His predictions for reaching Longevity Esca…

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#17 How the $101M XPRIZE will reverse aging by 20 years | Jamie Justice 1:50:20

10M ago1:50:20

1:50:20

Jamie Justice takes us inside the $101M XPRIZE Healthspan competition - one of the world's largest efforts to develop therapeutics that could reverse aging. As Executive Vice President of XPRIZE Healthspan, Jamie reveals how teams must demonstrate they can restore muscle, cognitive, and immune function in older adults within just one year. The stak…

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Body Health = Brain Health 9:00

10M ago9:00

9:00

What's the secret to supporting a sharp mind at any age? In this program, Dr. Nancy Isenberg discusses the latest science-based practices to promote brain health and resiliency as we age. Series: "Osher WISE: Well-being and Integrative Science for Everyone" [Health and Medicine] [Show ID: 40508]By UCTV: UC San Francisco

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#16 Critical health signals your doctor is overlooking | David Luu 1:52:41

10M ago1:52:41

1:52:41

A pediatric cardiac surgeon turned longevity pioneer, Dr. David Luu shares his journey from humanitarian medical missions to building a global network of physicians focused on prevention. Learn about critical health markers your doctor might be missing, how AI is transforming healthcare, the truth about longevity interventions, and why the future b…

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#15 Fifty years of fighting death | James Strole 1:41:56

11M ago1:41:56

1:41:56

🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership 🚀 Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: https://peterottsjo.beehiiv.com/ …

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What Everyone Needs to Understand About Healthspan 9:52

11M ago9:52

9:52

This video is designed to introduce friends who may be unfamiliar with the concept of healthspan. Healthspan refers to the portion of our lives spent in good health, free from chronic diseases and significant physical or cognitive decline. It’s a key focus in geroscience and longevity medicine, areas dedicated to understanding aging and extending h…

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Aging Health and the Power of Lifestyle Choices with Gordon Saxe 32:59

11M ago32:59

32:59

Gordon Saxe, M.D., Ph.D., reveals the secrets to slowing down the aging process and living a healthier life. He uncovers how aging affects everything from our bones and muscles to our brain, leading to issues like memory loss, fatigue, and weakened immune responses. How can you make choices today that could help you live longer and feel better? Sax…

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Transferring Knowledge into Transformation: Building Lasting Personal Change through Awareness Intention and Action with Anthony Lim 29:56

11M ago29:56

29:56

Anthony Lim, M.D., J.D., explores how small, intentional steps can lead to lasting behavioral change. Lim breaks down a simple, four-step framework—awareness, intention, action, and reflection—to help people achieve their goals, whether it's improving health, forming better habits, or making positive life changes. Through real-life examples and ins…

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#14 The hidden link between baby gut health and chronic disease | Nora Cavani 1:47:51

12M ago1:47:51

1:47:51

🚀 Special offer for our LEVITY audience: Join Vitalism today and receive a 30% discount on your membership using the code LEVITY at checkout. https://www.vitalism.io/membership 🚀 Show notes for this episode will be available soon after this airs. Sign up for the LEVITY newsletter to get them straight to your inbox: https://peterottsjo.beehiiv.com/ …

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Ancient Wisdom Modern Science and the Emerging Keys to Healthy Aging and Longevity - Lee Tuh-Fuh and Ruby Lee Wang Zu-Ming Endowed Lecture 1:39:46

1y ago1:39:46

1:39:46

Examine how what we eat and how we live can promote wellness, enhance immunity, combat age-related diseases, and promote longevity. Gordon Saxe, M.D., Ph.D., and Anthony Lim, M.D., J.D., share a timeless perspective, supported by their own research and clinical experience, on how optimal nourishment, purposeful reflection, health movement, and gene…