Best MECO Podcasts (2025)

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The Biotech Hiring Secret Sauce with Colin Smith, ExecNow CEO 52:55

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6d ago52:55

52:55

Biotech is bursting with innovation—from gene editing to AI-powered diagnostics—but behind every successful breakthrough is something far less talked about: leadership. In this episode of Inside Biotech, we’re joined by Colin Smith, CEO and co-founder of ExecNow, a next-gen talent partner helping some of the world’s most innovative biotech, greente…

1
T+304: The Musk/Trump Breakup, Jared Isaacman’s Withdrawn Nomination, and Starship Flight 9 (with Lori Garver) 49:36

17d ago49:36

49:36

Lori Garver, former NASA Deputy Administrator, joins me to talk about the chaos of the last week: the withdraw of Jared Isaacman’s nomination for NASA Administrator, Starship Flight 9, and of course, the wild public breakup of Elon Musk and President Trump. This episode of Main Engine Cut Off is brought to you by 33 executive producers—David, Donal…

1
Alliance Has Direction 51:43

21d ago51:43

51:43

In this episode, Joe and Richard explore the difference between community and alliance: “An alliance is going someplace… it has direction.” They trade time-travel hypotheticals, reflect on the problem-solving joy of The Martian and The Last of Us, and debate whether their businesses are behaving like nouns or verbs. “Do something with this,” Joe in…

1
Solid Diagonal Line Up: Anthony Colangelo & MECO's origin story 51:54

1M ago51:54

51:54

While Richard was away Joe catches up with Anthony Colangelo, partner at Pine Works, host of Main Engine Cut Off & cohost of Off-Nominal, Engineering leader, iOS product developer, birds fan, dad, and Joe's spiritual nephew. Anthony has grown a space flght, exploration, and policy podcast empire rooted in his sincere passion and strong opinions re:…

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CRISPR Campaigns & Beyond: Science Marketing with Elizabeth Chabe, Founder/CEO of High Touch Group 56:55

1M ago56:55

56:55

What does it really take to bring cutting-edge science out of the lab and into the world? In this episode of Inside Biotech, we sit down with Elizabeth Chabe, founder and CEO of High Touch Group, a strategic marketing firm specializing in biotech, medtech, and deep tech. Elizabeth shares her unique journey—from working in a structural engineering l…

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T+303: The Trump 2024 Transition (with Mark Albrecht) 53:42

2M ago53:42

53:42

Mark Albrecht joins me to talk about his time on the Trump 2024 Transition Team, the thinking behind some of the policy decisions we’re starting to see in the space and national security spheres, and more. This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, The Astrogators at SEE, Will and Lars from Agile, Theo a…

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T+302: A Tour of Marotta Controls 1:38:45

2M ago1:38:45

1:38:45

We take a tour of Marotta Controls in Montville, New Jersey, to see how they work, how they develop, produce, and test products at rate, and we learn about the most feared topic in space—valves! This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, Josh from Impulse, Heiko, Donald, Stealth Julian, Warren, Kris, Fra…

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T+301: Hypersonics and Constellations (with Caleb Henry) 42:05

2M ago42:05

42:05

Caleb Henry, Director of Research at Quilty Space, joins me to talk megaconstellations, the hypersonics industry, and more. This episode of Main Engine Cut Off is brought to you by 33 executive producers—Joonas, Josh from Impulse, Heiko, Donald, Stealth Julian, Warren, Kris, Frank, Steve, Bob, Better Every Day Studios, The Astrogators at SEE, Joaki…

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T+300: Isaacman’s Confirmation Hearing, NASA and NOAA Budgets, NSSL Phase 3 Lane 2 Awards 26:48

2M ago26:48

26:48

Jared Isaacman was in Congress for a confirmation hearing for his nomination as NASA Administrator, which was followed up by reports of huge proposed budget cuts at NASA and NOAA. And as expected, SpaceX, ULA, and Blue Origin all received awards for NSSL Phase 3 Lane 2. This episode of Main Engine Cut Off is brought to you by 33 executive producers…

1
From Neuroscience to OmBiome: Dr. Julia Perederiy on Building a Science-Backed Wellness Brand 52:06

2M ago52:06

52:06

In this episode of Inside Biotech, we sit down with Dr. Julia Perederiy, neuroscientist and Founder of OmBiome, a regenerative health company revolutionizing personal care through microalgae. Julia shares her journey from academia to entrepreneurship, the science behind her mission, and how wellness trends are evolving in today’s market. Tune in fo…

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eHouse Gets Acquired: Reaction Pod + The Philadelphia Experiment starts! 46:00

2M ago46:00

46:00

Richard and Joe break down their conversation with Chris & Aaron Quinn, more details about agency acquisitions, private equity vs venture capital, and they spill the beans about The Philadelphia Experiment April 9-11.By Joe Rinaldi & Richard Banfield

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Little By Little, Then All At Once: eHouse Gets Acquired 56:37

3M ago56:37

56:37

Chris and Aaron Quinn join to share their experiences creating, growing, and ultimately scaling eHouse through an acquisition. Thanks to our friends for being so candid and informative about their experiences!By Joe Rinaldi & Richard Banfield

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T+299: Starliner, According to Butch and Suni (with Eric Berger) 28:50

3M ago28:50

28:50

Eric Berger of Ars Technica joins me to talk about his recent interviews with Butch and Suni in the aftermath of their flight, the update NASA put out about Starliner, and how it all lands from where we are now. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Ryan, David, Theo and Violet, Fred, Steve, Warren, The Ast…

1
T+298: Eric Schmidt Takes Over at Relativity, Rocket Lab Plans Mynaric Acquisition 20:05

3M ago20:05

20:05

Eric Schmidt has taken a majority stake in Relativity and will serve as its CEO, so this is a good time to check in on their plans. Rocket Lab is planning to acquire Mynaric, and I have a theory I felt like I needed to float. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Matt, Donald, Frank, David, Lee, Will and La…

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T+297: Firefly Blue Ghost 1, Intuitive Machines IM-2, SpaceX Starship Flight 8 (with Josh Dinner) 52:20

4M ago52:20

52:20

Josh Dinner of Space.com joins me to talk about a wild week in space—Firefly’s Blue Ghost 1, Intuitive Machines’ IM-2, SpaceX’s Starship Flight 8, Rocket Lab announcements, and more. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Stealth Julian, Kris, Heiko, Pat, Jan, Warren, Josh from Impulse, Ryan, Lee, Joel, Davi…

1
Repurposing Drugs & Reinventing Biotech: Dr. Adam Watson on Building MeCo Diagnostics 59:52

4M ago59:52

59:52

In this discussion, Dr. Adam Watson, Co-founder and CEO of MeCo Diagnostics, shares the personal and professional experiences that led him to focus on cancer research and, ultimately, to launch his own company. From the profound influence of his family’s battle with cancer to the long and complex journey of developing the MeCo Score™, he walks us t…

1
Take the Credit Out & Get More Done 30:12

4M ago30:12

30:12

Duolingo announced changing their job titles from UX Design to Product Experience Design and created a 2013-Twitter-era dust up so Richard and Joe chime in with their thoughts. We discuss the purpose of job titles, the way identity effs with you, and to bring it back to sales in a meta way we ask what's more important? That you achieve your objecti…

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T+296: Jim Bridenstine on Space Policy 25:56

4M ago25:56

25:56

Former Congressman and NASA Administrator Jim Bridenstine joins me to talk space policy, then and now: CLPS, Commercial Space Stations, Artemis, international partnerships, and more. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Stealth Julian, Kris, Heiko, Pat, Jan, Warren, Josh from Impulse, Ryan, Lee, Joel, Davi…

1
T+295: The Economics of Space (with Matthew Weinzierl and Brendan Rosseau) 41:11

4M ago41:11

41:11

Matthew Weinzierl and Brendan Rosseau join me to talk about their new book, Space to Grow: Unlocking the Final Economic Frontier. We talk about the economics driving the space industry today, how traditional economic theories apply—or not!—to the industry, and how to use economics as a lens to shape your business and policy approach to the future. …

1
Waiting Super Hard is Your Biz Dev Strategy 47:14

4M ago47:14

47:14

This episode has it all!Richard shares how embedding "brown M&M" contract requirements helps you get what you wantHe also discusses how the TNT (takes no talent) parts of a business lead to successJoe provides an example: Respond to new leads shockingly quickly and meet your clients' enthusiasmRichard describes his tantric response to awkward silen…

1
The Medium & The Message 53:26

4M ago53:26

53:26

Richard and Joe discuss the little cohort/therapy group they're in and how beneficial that relationship has become over the past year. Within that discussion Richard explains how effective it can be to manage communication patterns within a community, for example conducting types of conversations in person while conducting very different conversati…

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T+294: Elon Musk and the Trump Administration, Potential SLS Cancellation (with Eric Berger) 42:22

4M ago42:22

42:22

Eric Berger of Ars Technica joins me to talk about Elon Musk and the whirlwind start of the second Trump administration, and what the future may hold for SLS. This episode of Main Engine Cut Off is brought to you by 31 executive producers—Will and Lars from Agile, Fred, The Astrogators at SEE, Ryan, Stealth Julian, Warren, Joakim (Jo-Kim), Tim Dodd…

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Zero Forecasting & Overinvesting in Biz Dev Seasons 47:00

5M ago47:00

47:00

There's a few big ideas in this week's episode. Richard makes a strong case that Pipedrive weighted outcome forecasting for open opportunities and leads is steering you wrong. It's 0% forecastable revenue until the check clears.Joe says tracking sales quarterly sets you up to fail. There are two selling seasons and two off-seasons every year, plan …

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T+293: Jonathan’s Space Report Library Transition (with Jonathan McDowell) 14:21

5M ago14:21

14:21

Jonathan McDowell—astrophysicist at Harvard-Smithsonian Center for Astrophysics and the namesake of the McDowell Line at 80 kilometers—joins me to talk about his fundraiser to move his epic space library to a new, permanent home. Let’s help him out! This episode of Main Engine Cut Off is brought to you by 32 executive producers—Frank, Lee, Joel, Th…

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T+292: New Glenn Flight 1, Starship Flight 7 22:56

5M ago22:56

22:56

Blue Origin flew New Glenn successfully for the first time, and SpaceX flew Starship for the seventh time. Both featured failures at different points of the flight, with the impacts on Starship being significantly bigger than those on New Glenn. This episode of Main Engine Cut Off is brought to you by 32 executive producers—Frank, Lee, Joel, Theo a…

MECO Podcasts

1
Main Engine Cut Off

Anthony Colangelo

1
You Can't Lose!

Joe Rinaldi & Richard Banfield

1
Inside Biotech

Gabriella Rubert, Daniel Arce, Katherine Merkling, Serena Gao, Bryan Jimenez, Danielle Luu, Stephanie Wu

1
The Seachange Business Podcast

Michael Vincent

1
The Biotech Hiring Secret Sauce with Colin Smith, ExecNow CEO 52:55

1
T+304: The Musk/Trump Breakup, Jared Isaacman’s Withdrawn Nomination, and Starship Flight 9 (with Lori Garver) 49:36

1
Alliance Has Direction 51:43

1
Solid Diagonal Line Up: Anthony Colangelo & MECO's origin story 51:54

1
CRISPR Campaigns & Beyond: Science Marketing with Elizabeth Chabe, Founder/CEO of High Touch Group 56:55

1
T+303: The Trump 2024 Transition (with Mark Albrecht) 53:42

1
T+302: A Tour of Marotta Controls 1:38:45

1
T+301: Hypersonics and Constellations (with Caleb Henry) 42:05

1
T+300: Isaacman’s Confirmation Hearing, NASA and NOAA Budgets, NSSL Phase 3 Lane 2 Awards 26:48

1
From Neuroscience to OmBiome: Dr. Julia Perederiy on Building a Science-Backed Wellness Brand 52:06

1
eHouse Gets Acquired: Reaction Pod + The Philadelphia Experiment starts! 46:00

1
Little By Little, Then All At Once: eHouse Gets Acquired 56:37

1
T+299: Starliner, According to Butch and Suni (with Eric Berger) 28:50

1
T+298: Eric Schmidt Takes Over at Relativity, Rocket Lab Plans Mynaric Acquisition 20:05

1
T+297: Firefly Blue Ghost 1, Intuitive Machines IM-2, SpaceX Starship Flight 8 (with Josh Dinner) 52:20

1
Repurposing Drugs & Reinventing Biotech: Dr. Adam Watson on Building MeCo Diagnostics 59:52

1
Take the Credit Out & Get More Done 30:12

1
T+296: Jim Bridenstine on Space Policy 25:56

1
T+295: The Economics of Space (with Matthew Weinzierl and Brendan Rosseau) 41:11

1
Waiting Super Hard is Your Biz Dev Strategy 47:14

1
The Medium & The Message 53:26

1
T+294: Elon Musk and the Trump Administration, Potential SLS Cancellation (with Eric Berger) 42:22

1
Zero Forecasting & Overinvesting in Biz Dev Seasons 47:00

1
T+293: Jonathan’s Space Report Library Transition (with Jonathan McDowell) 14:21

1
T+292: New Glenn Flight 1, Starship Flight 7 22:56