Speaking of Mol Bio, a podcast series from Thermo Fisher Scientific, discusses trending applications in science and the molecular biology aspects of those applications. Our host delves in to deep discussion with CEOs, R&D scientists, researchers, and key opinion leaders across the globe. Speaking of Mol Bio helps scientific curious people - from all scientific and non-scientific backgrounds - understand how modern molecular biology applications can help push the boundaries in medicine, scien ...
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Molecules, microbes and multiomics is DNA Genotek's podcast, featuring experts in all areas of the genomics, microbiome and multiomics space. To learn more about any of these emerging areas of science, tune in.
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Proteomics in Proximity discusses the intersection of proteomics with genomics for drug target discovery, the application of proteomics to reveal disease biomarkers, and current trends in using proteomics to unlock biological mechanisms. Co-hosted by Olink's Dale Yuzuki, Cindy Lawley and Sarantis Chlamydas.
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Hear directly from the people whose work in genomics is shaping the way we think about science and our world. Listen as leading scientists discuss the impact of genomics with the Illumina Scientific Affairs team. Download or subscribe to our recurring podcasts.
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The hidden language of RNA – how epigenetics is shaping medicine
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31:51This episode teaches that innovation is born at the intersection of curiosity and persistence. Dr. Gudrun Stengel, co-founder and CEO of Alida Biosciences, reveals how her startup is transforming the landscape of RNA research through a novel technology called proximity barcoding. Dr. Stengel’s story exemplifies the power of entrepreneurial spirit i…
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Sustainability made simple – greener choices in molecular biology
10:21
10:21
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10:21Sustainability in the lab isn't just a trend—it's a responsibility. In this quick but powerful Mol Bio Minutes episode, sustainability expert Sune Lund Sporring shares actionable tips to reduce energy use, manage lab waste, and transition to greener materials like Thermo Fisher’s Sustain Series bio-based plastics. Discover the difference between bi…
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From bats to cancer – the power of gene regulation
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33:53
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33:53Join us for an insightful conversation with Dr. Nadav Ahituv, a leader in human genetics and gene regulation at UCSF. He shares his personal journey from scoliosis patient to genetic researcher, exploring the mysteries of non-coding DNA, massively parallel reporter assays, and CRISPR-based therapeutic innovations. We dive into his lab’s diverse pro…
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No more smears – expert tips for electrophoresis success
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9:05With prior Mol Bio Minutes episodes covering DNA form migration and staining considerations for nucleic acid gel electrophoresis, we tie it all together with this great set of overall tips, tricks and resources for the topic. Anyone that’s ever run a gel has undoubtedly produced gels with smeared, faint or poorly separated bands. What causes these …
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Biologically removing the forever from “forever chemicals”
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32:00
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32:00It could be argued that biology has always boiled down to chemistry, and that chemistry has always boiled down to physics. However, not many would deny that the fields of biology and chemistry are overlapping more than ever, with both leveraging computing methods, also more than ever. This conversation with Dr. Ramesh Jha, Technical Staff Member at…
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AI Powered Multiomics: Joachim Schmid on Data Analysis at Illumina
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A clear picture – staining tips for gel electrophoresis
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10:17You can run the perfect agarose gel to separate your nucleic acid fragments but if you don’t stain and image the gel properly, it’s all for not. In this second installment of Mol Bio Minutes we take a look at the staining considerations for nucleic acid gel electrophoresis with Paulius Palaima, Product Manager at Thermo Fisher Scientific. He covers…
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With knowledge comes great responsibility
35:37
35:37
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35:37Topics and terms such as biosafety, biosecurity, containment, and contamination are things most of us have heard of and think about at some level, but with the pace of molecular biology moving faster than ever, these are topics with implications that are reaching farther than ever. We’re joined by Dr. Ryan Burnette and Dr. Lauren Richardson from Me…
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DNA on the move – the influence of form on gel migration
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9:19Agarose gel electrophoresis is a staple method in almost all biology and biochemistry lab where separation and analysis of nucleic acids is needed. In this Mol Bio Minutes mini episode Augustė Užuotaitė, Scientist III at Thermo Fisher Scientific, covers the basics of electrophoresis with a spotlight on how different forms of DNA migrate differently…
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A glimpse into product management and PMWC plans with Jenny Samskog
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32:36Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: Olink® Reveal, accessible NGS-based proteomics for every lab: https://olink.com/products/olink-reveal Olink tools and software · Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://o…
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The Genomic Revolution Transforming Public Health in Africa with Next-Generation Sequencing (NGS) with Professor Martin Nyaga
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Proteomics in hundreds of thousands: Prof Sir Rory Collins and Dr Chris Whelan
48:54
48:54
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48:54Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: Olink tools and software · Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/ · Olink® Explore HT, Olink’s most advanced solution for high-throu…
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The genetics and neuroendocrinology of obesity
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31:37Obesity is one of the most pressing health challenges of our time, with genetic and molecular factors playing a crucial role in how our bodies regulate weight. In this season opener, we explore the science behind obesity, focusing on how hormones, genetics, and brain circuits influence feeding behavior and body weight. Join us for a fascinating dis…
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Season 3 spoilers – innovation, inspiration, and insight
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4:36
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4:36The start of Season 3 is just around the corner, slated to start in January 2025. What’s the new season hold in store you might ask? Steve assures us he’ll be back hosting Season 3 and teases at topics that are coming. These include biosecurity, bioengineering, polymer degradation, genetics of obesity, CROs and how they utilize mol bio, platelet bi…
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It’s all in your approach – biosynthesis of natural products
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33:18We’re joined in this episode by Dr. Sarah Barry, Reader in Chemical Biology at King’s College London. Sarah started with an interest in biochemistry, went into organic chemistry because it was more concrete, and now applies her chemist’s approach to understanding and manipulating biosynthesis of natural products for important areas of research, inc…
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Decoding Aging and the Environment with Cornelia van Duijn
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56:58Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: Olink tools and software Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/ Olink® Explore HT, Olink’s most advanced solution for high-throughpu…
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The history of fermented foods like beer, bread, and other foods can be traced back thousands of years to ancient civilizations in China and Egypt. This ancient technology was originally used to preserve foods when refrigeration was not an option. While less common in modern industrialized civilizations, we’re now realizing that fermented foods pla…
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Therapeutic nucleic acids – a CDMO’s view on mRNA
32:04
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32:04While some of us knew a good bit about mRNA prior to 2020, we all got a crash course on mRNA technology and its prophylactic and therapeutic potential as a result of the COVID pandemic and subsequent SARS CoV-2 vaccine development. In fact, most of us have now received at least one mRNA vaccine at this point. Our guest for this episode, Dr. Christi…
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There are all sorts of molecular tests to tell if you’re infected with something specific, but what do you use when you’re not sure what you might have? You might use a thermometer as a first step, but wouldn’t it be nice if that thermometer was a bit more high tech? In this episode we meet Dr. Nick Meyerson, CEO and co-founder of Darwin Bioscience…
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Plastics are a modern miracle of science that have helped deliver both convenience and life-saving solutions. However, we must now grapple with the challenge of immense amounts of plastics in our waste streams and environment. How do we best deconstruct plastics to reusable or more bio-friendly molecules? This is the exact challenge being addressed…
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Scientific marketing in the century of the biotech revolution
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32:37Most scientists start their education and careers with a vision of working in the lab to discover great things and drive innovation. However, we don’t all end up loving the actual lab work portion of science. What non-lab career options exist to utilize molecular biology knowledge and skills? Well, according to our guest, Jason Amsbaugh, Founder an…
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While the end product is quite different, brewing beer is not all that different than many other bioproduction processes used in the lab and industry. Both require skills, experience, and the right QC/QA methods to control and monitor the starting materials and the entire process, all the way to that bottle of suds you might be thirsty for. Steve a…
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Illumina Scales Variant Calling and Genome Interpretation to Improve Gaps in Genetic Testing
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31:19
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How Do You Train Genomics AI? On Natural Selection Itself, Says VP of Illumina's AI Lab, Kyle Farh
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Two Industry Leaders on the Growing Complexity of Genomic Cancer Data
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When you buy chicken or turkey from the grocery store, you might not give it much thought, but there is an entire network of people working to ensure the health of the animals in our food supply chain and your health. In this episode, we talk with an unsung hero, Beverly Wood, supervisor of the molecular diagnostics lab at the North Carolina Depart…
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Does finding a rare mutation accomplish anything?
4:34
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Clinical utility of ctDNA testing in lung cancer
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Molecular Biology for hire – the CRO experience
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31:53Contract Research Organizations (CROs) are a resource that most scientists know about but relatively few have first-hand, internal experience with. In this episode our hosts speak with Saboor Hekmaty, Director of Laboratory Operations at Avrok Biosciences, who pulls back the curtain to illuminate what CROs do, and the skills required for them to be…
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Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: UK Biobank Pharma Proteomics Project (UKB-PPP), one of the world’s largest scientific studies of blood protein biomarkers conducted to date, https://www.ukbiobank.ac.uk/learn-more-about-uk-biobank/news/uk-biobank-launches-one-of-the-lar…
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High-throughput transcriptomics and AI for drug discovery
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31:56Doing something complex and meaningful in a new way requires thinking and acting a bit differently. This is the case with how Dr. Joey Azofeifa, from Arpeggio Bio, is using systems biology to discover new drug candidates. Join us in this Season 2 kickoff episode where we dive headlong into transcriptomics, systems biology, machine learning, and lea…
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We start the second season of this series with an update on what you can expect from new episodes, which start to drop soon. Your host, Steve Lewis, shares details on changes you can expect as the series evolves. One change will be a broadening of application topics to be covered, as this season will include episodes discussing transcriptomics in b…
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How proteomics is shaping pharma strategies
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43:54
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43:54Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources mentioned in this episode: Olink tools and software • Olink® Explore 3072, the platform utilized by the UK Biobank to measure ~3000 proteins in plasma: https://olink.com/products-services/explore/ • Olink® Explore HT, Olink’s most advanced solution for high-throu…
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Proteogenomics of metabolic disease with Mine Koprulu and Dr. Claudia Langenberg
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44:45Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources from this episode: Published study of primary focus Koprulu M, Carrasco-Zanini J, Wheeler E, Lockhart S, Kerrison ND, Wareham NJ, Pietzner M, Langenberg C. Proteogenomic links to human metabolic diseases. Nat Metab. 2023 Mar;5(3):516-528. doi: 10.1038/s42255-023-…
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Pan-cancer blood proteome profiling with María Bueno Álvez (SciLifeLab)
42:49
42:49
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42:49Welcome to the Olink® Proteomics in Proximity podcast! Below are some useful resources from this episode: Published study of primary focus Álvez MB, Edfors F, von Feilitzen K, Zwahlen M, Mardinoglu A, Edqvist PH, Sjöblom T, Lundin E, Rameika N, Enblad G, Lindman H, Höglund M, Hesselager G, Stålberg K, Enblad M, Simonson OE, Häggman M, Axelsson T, Å…
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In this episode of Speaking of Mol Bio, we speak with Dr. Mandovi Chatterjee about single cell analysis. Dr. Chatterjee is the Director of Single Cell Core at Harvard University Medical School. She has spent her career at the exploring and mastering a wide variety of single cell methods . In conversation with Dr. Chatterjee, our hosts dive into the…
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Breaking new ground in PTSD research: Insights from The Consortium for Post-Traumatic Stress Disorders
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45:34In this episode, Ajin Abraham (Strategic Marketing Manager, Genomics) and Sanna Abbasi, Ph.D. (Scientific Writer/Content Specialist) interview a group of leaders in the Psychiatric Genomics Consortium for Post-Traumatic Stress Disorders (PGC-PTSD). The purpose of the Psychiatric Genomics Consortium is to unite investigators around the world to cond…
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Welcome to Olink Proteomics in Proximity Podcast! Below are some useful resources from this episode: Highlighted publication: Girerd N, et al. Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circ Heart Fail. 2023 May;16(5):…
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The intersection of biology and technology
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38:45
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38:45In this episode, the hosts have an intriguing discussion with Dr. Ben Sun, Head of Biomarker Genetics at Biogen. Dr. Sun holds an MD/PhD from the University of Cambridge, providing a view and perspective on data from both research and clinical perspectives. The advantage of his unique background is that it provides a balanced perspective on large-s…
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Interview about the UK Biobank with Dr. Christopher Whelan
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36:56Welcome to Olink Proteomics in Proximity Podcast! Below are some useful resources from this episode: Highlighted article from the UK Biobank Pharma Proteomics Project (UKB-PPP): Styrkarsdottir U, Lund SH, Thorleifsson G, Saevarsdottir S, Gudbjartsson DF, Thorsteinsdottir U, Stefansson K. Cartilage Acidic Protein 1 in Plasma Associates With Prevalen…
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Multi-omics | The molecular biology of plants in space
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31:59
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31:59Dr. Stan Roux, Professor of Molecular Biosciences at the University of Texas – Austin, has had a long and successful career based on his fascination with plants and his desire to understand plant biology. He’s spent his career exploring the effect of apyrase on root systems, crop yields, and plant nutrient uptake. We get into Stan’s unlikely career…
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CRISPR | An insider’s perspective on CRISPR
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31:39
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31:39In this episode, Gabriel and Steve welcome a colleague of theirs, Dr. Doris Beylkin, to share her depth of knowledge and perspective on the CRISPR cell engineering topic. While Doris is a Global Market Development Manager today, she has over 10 years of experience supporting customers in planning, troubleshooting, and analyzing gene modulation and …
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Empowering breast cancer proteomics with genomics with Dr. Jochen Schwenk
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44:39Welcome to Olink Proteomics in Proximity Podcast! Below are some useful resources from this episode: Highlighted pre-print article: Malarstig A, Grassman F, Dahl L, et al. Evaluation of Circulating Plasma Proteins in Breast Cancer: A Mendelian Randomization Analysis. ResearchSquare 2023.04.04. DOI: https://doi.org/10.21203/rs.3.rs-2749047/v1 Highli…
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Expand into multi-omics: DNA Genotek and Diversigen 2021 grant program winner
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17:17In this podcast, we interview Dr. Jonas Schluter, Assistant Professor from the Department of Microbiology at the Grossman School of Medicine at NYU Langone Health and a winner of the DNA Genotek and Diversigen 2021 Expand into Multi-omics grant, discuss his research.
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Exosomes | The early realization of the exosome’s potential
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32:11This discussion with Dr. Johan Skog covers a lot of ground while staying super approachable. The Founder and Chief Scientific Officer of Exosome Diagnostics, starts by sharing basics about exosomes and tells us about how he’s translated his curiosity for the vesicles from tumor stem cells into his current role where he’s helped develop the world’s …
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DUOX2, IL-17C, and IBD (Inflammatory Bowel Disease)
30:09
30:09
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30:09Welcome to Olink Proteomics in Proximity Podcast! Below are some useful resources from this episode: Highlighted publication: Grasberger H, Magis AT, Sheng E, Conomos MP, Zhang M, Garzotto LS, Hou G, Bishu S, Nagao-Kitamoto H, El-Zaatari M, Kitamoto S, Kamada N, Stidham RW, Akiba Y, Kaunitz J, Haberman Y, Kugathasan S, Denson LA, Omenn GS, Kao JY. …
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Welcome to Olink Proteomics in Proximity Podcast! Below are some useful resources from this episode: Highlighted publication: Diaz-Canestro C, Chen J, Liu Y, Han H, Wang Y, Honoré E, Lee CH, Lam KSL, Tse MA, Xu A. A machine-learning algorithm integrating baseline serum proteomic signatures predicts exercise responsiveness in overweight males with p…
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Exosomes | Exploring the body’s extracellular delivery system
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32:09It’s been 40 years since extracellular vesicles, or exosomes, were first connected to the way cells communicate and transfer information. Since then, researchers have studied what part they play in the normal physiology of a cell. There has also been an expanding amount of work in the role that exosomes can play in therapeutics and diagnostics of a…
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