Best NEJM Group Podcasts (2025)

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Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group

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27d ago

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Time Stamps 00:48 Background on Beta Blockers and Their Mechanism 02:41 Historical Context of Beta Blockers in Heart Disease 04:56 Capricorn Trial and Its Impact 07:17 Emergence of Doubts About Beta Blockers 10:09 Introduction to the REDUCED-AMI Trial 15:52 Discussion on Trial Interpretation and Clinical Implications 16:18 Comparison with Other Tri…

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#180 Beta-Blockers & REDUCE-AMI Trial: Beyond Journal Club Segment with NEJM Group 26:41

27d ago26:41

26:41

How much do beta blockers help after a heart attack, even when the heart’s pumping well? In this episode, we revisit the origins of beta blockers in post-MI care, examine how evidence evolved, and explore the REDUCE-AMI trial, which questions whether beta blockers are still needed for all. Listen to this latest episode of Beyond Journal Club, a col…

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Diagnose the Clinician: Hoofbeats Segment

16h ago

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Time Stamps 00:02 Case Presentation and Initial Diagnosis 02:47 Tachycardia and Early Impressions 04:10 Clinical Deterioration and New Clues 07:19 Problem Representation and Reflection 21:45 Lessons on Reasoning and Bias 26:55 Final Takeaways and Action Steps Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025 T…

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#183 Diagnose the Clinician: Hoofbeats Segment 33:11

1d ago33:11

33:11

What went wrong? What were the reasoning or contextual missteps that led us astray? 🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025 🔹 Transcript and Show Notes Timestamps: (00:02) | Case Presentation and Initial Diagnosis (02:47) | Tachycardia and Early Impressions (04:10) | Clinical Deterioration and New …

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NEJM Interview: Peter Marks on the disruption of traditional approaches to establishing Covid-19 vaccine policy in the United States. 9:57

6d ago9:57

9:57

Peter Marks is the former director of the FDA Center for Biologics Evaluation and Research. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P. Marks. The Role of Public Health Agencies in Creating Vaccine Policy. N Engl J Med 2025;393:209-211.

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NEJM This Week — July 17, 2025 21:24

6d ago21:24

21:24

Featuring articles on gastric and gastroesophageal junction cancer, pulmonary sarcoidosis, graft-versus-host disease, gastroenteritis in children, the rapid recovery of donor hearts after circulatory death, and an on-table reanimation of a pediatric heart from donation after circulatory death; a review article on fragile X disorders; a case report …

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Can AI Accelerate Science? Dr. Andy Beam on AI’s Next Frontier 1:07:28

6d ago1:07:28

1:07:28

Dr. Andy Beam has trained models, mentored scientists, and used data to quantify the value of treatments. In this episode of NEJM AI Grand Rounds, Raj Manrai turns the table on his co-host, reflecting on how Andy’s childhood misdiagnosis, and the failure of human recall, revealed the diagnostic promise of machine learning. As a Harvard professor, h…

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NEJM Interview: Patricia Mae Santos on the effects of U.S. anti-immigrant policies on immigrant health care workers and their patients. 11:00

13d ago11:00

11:00

Patricia Mae Santos is an assistant professor in the Department of Radiation Oncology at Emory University School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P.M.G. Santos, R. Jagsi, and C.I.A. Oronce. Who Will Care for America? Immigration Policy and the Coming Health Workforce Crisis. N Engl J …

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NEJM This Week — July 10, 2025 20:22

13d ago20:22

20:22

Featuring articles on mild asthma, cardiovascular risk factors, stroke, advanced breast cancer, and transforming health care; a review article on juvenile idiopathic arthritis; a case report of a man with headache and ataxia; and Perspectives on who will care for America, on hospital financial assistance policies, and on libraries burned, and a lif…

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Pleural Effusions: 5 Pearls Segment

13d ago

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Time Stamps Interpretation of Pleural Fluid Studies and Common Pleural Diseases Imaging Pearls and Thoracentesis Indications Deciding on Thoracentesis Light’s Criteria and Pseudo Exudates Pleural Fluid Studies: pH and Cell Differential Diagnosing and Treating Parapneumonic Effusions Malignant Pleural Effusions: Diagnosis and Management Sponsor: Oak…

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#182 Pleural Effusions: 5 Pearls Segment 36:15

13d ago36:15

36:15

Imaging Pearls | (01:12) Deciding on Thoracentesis | (04:00) Light’s Criteria and Pseudoexudates | (07:00) Pleural Fluid Studies: pH and Cell Differential | (16:56) Diagnosing and Treating Parapneumonic Effusions | (23:32) Malignant Pleural Effusions: Diagnosis and Management | (30:39) 🔹 Sponsor: Oakstone CME’s ACP MKSAP Audio Companion Use the cod…

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NEJM Interview: Erin Fuse Brown on the manifestations and effects of corporatization in health care. 11:11

20d ago11:11

11:11

Erin Fuse Brown is a professor of health services, policy, and practice at the Brown University School of Public Health and a member of the Journal’s Perspective Advisory Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.C. Fuse Brown. Defining Health Care “Corporatization”. N Engl J Med 2025;393:1-3.…

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NEJM This Week — July 3, 2025 26:06

20d ago26:06

26:06

Featuring articles on structured exercise after chemotherapy for colon cancer, and treatments in obesity, in head and neck cancer, and in patients at high risk for cardiovascular events; a review article on forensic pathology; a Clinical Problem-Solving on caving in to pressure; a Sounding Board on climate change and human health; and Perspectives …

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July Stories 3.0

20d ago

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Time Stamps 00:43 Worst Doctor Ever 07:15 First Night Shift 11:12 Imposter Syndrome 13:54 Lean on One Another Previous Episodes July Stories (2019) July Stories July Stories 2.0 (2023) July Stories 2.0 Transcript Dr. Shreya Trivedi: It’s that time of year again. Dun, dun, dun, July. And at Core IM we like to add some levity and realness with some h…

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#181 July Stories 3.0 15:58

20d ago15:58

15:58

Listen for some good laughs and relatable stories! In this episode, we share raw and real stories from July — from rapid responses to unexpected kindness — and reflect on the emotional weight of starting out in medicine. 🔹 Sponsor: NEJM Fellowship Program, click here to learn more and/or apply! Due Aug 1, 2025 🔹 Transcript and Show Notes Prior July…

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NEJM Interview: Dariush Mozaffarian on the health harms of ultraprocessed foods and related policy actions. 17:05

27d ago17:05

17:05

Dariush Mozaffarian is the director of the Food is Medicine Institute at the Friedman School of Nutrition Science and Policy at Tufts University and a professor of medicine at Tufts University School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D. Mozaffarian. Regulatory Policy to Address Ultrapr…

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NEJM This Week — June 26, 2025 25:44

27d ago25:44

25:44

Featuring articles on routine cerebral embolic protection for TAVI, and treatments for cirrhosis due to MASH, BRAF V600E metastatic colorectal cancer, and Pompe’s disease; a new review article series on medical education; a case report of a woman with dyspnea on exertion; and Perspectives on addressing ultraprocessed foods, on the costs of dismantl…

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NEJM Interview: I. Glenn Cohen on the professional implications of the use of artificial-intelligence–based monitoring systems in medicine. 7:17

1M ago7:17

7:17

I. Glenn Cohen is a professor of law and deputy dean at Harvard Law School and faculty director of the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. I.G. Cohen, I. Ajunwa, and R.B. Parikh. Medical AI and Clinician Sur…

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NEJM This Week — June 19, 2025 23:07

1M ago23:07

23:07

Featuring articles on mismatch repair–deficient tumors, generalized myasthenia gravis, HER2-mutant non–small-cell lung cancer, a Corynebacterium diphtheriae outbreak, and hereditary and sporadic papillary kidney cancer; a review article on unruptured intracranial aneurysms; a case report of a man with respiratory failure and shock after kidney tran…

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Google’s Efforts to Build Patient-Facing AI: A Conversation with Drs. Alan Karthikesalingam and Anil Palepu 38:22

1M ago38:22

38:22

In this episode of NEJM AI Grand Rounds, guests Drs. Alan Karthikesalingam and Anil Palepu of Google walk co-hosts Raj Manrai and Andy Beam through the making and evaluation of AMIE, an AI system designed to conduct clinical conversations with patients. Alan and Anil explain how AMIE was trained using synthetic doctor-patient interactions generated…

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NEJM Interview: Amanda Kallen on the history of women’s health research and recent actions that are jeopardizing progress in women’s health. 12:45

1M ago12:45

12:45

Amanda Kallen is an associate professor in the Division of Reproductive Endocrinology and Infertility at the University of Vermont Larner College of Medicine and an adjunct professor at the Yale School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.N. Kallen and Others. Undermining Women’s Health…

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NEJM This Week — June 12, 2025 25:49

1M ago25:49

25:49

Featuring articles on treatments for pulmonary fibrosis, for obesity and overweight, for severe hemophilia B, and for a rare genetic disease; a review article on malnutrition in older adults; a case report of a man with a nasopharyngeal mass; a Medicine and Society on John Collins Warren; and Perspectives on undermining women’s health research, on …

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Invasive Fungal Disease: 5 Pearls Segment

1M ago

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Time Stamps 01:46 Pearl 1: What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? 10:35 Pearl 2: What are the main classes of fungi? 18:16 Pearl 3: Fungal Diagnostics: PCR/B-D Glucan and Galactomannan 29:42 Pearl 4: Blood Cultures, Sputum/BAL cultures, Urine cultures 34:14 Pearl 5: How is invasive fungal di…

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#179 Invasive Fungal Disease: 5 Pearls Segment 45:02

1M ago45:02

45:02

🔹 What is invasive fungal disease, and who is most at risk for developing invasive fungal disease? (~ 02:46) 🔹 What are the main classes of fungi? (~11:35) 🔹 What are the pros and cons of B-D Glucan and Galactomannan (~19:16) 🔹 How to increase the yield of blood cultures? How to interpret yeast growth in sputum/BAL and urine cultures? (~ 30:42) 🔹 H…

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NEJM Interview: David Jones on the disparate historical approaches to anemia diagnosis and their lessons for physicians. 40:04

2M ago40:04

40:04

Watch the NEJM In Studio video of this interview at NEJM.org. David Jones is the Ackerman Professor of the Culture of Medicine at Harvard University. Harleen Marwah, the interviewer, is an Editorial Fellow at the Journal. W. Xue and D.S. Jones. Debating Race and the Diagnosis of Anemia — How Medicine Moved Away from Race-Based Standards. N Engl J M…

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NEJM Interview: Amar Kelkar on NIH indirect-cost coverage and U.S. medical research. 7:55

2M ago7:55

7:55

Amar Kelkar is a physician at the Dana-Farber Cancer Institute and an instructor in medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.H. Kelkar. U.S. Research Leadership at a Crossroads — The Impact of Reducing NIH Indirect-Cost Coverage. N Engl J Med 2025;392:2081-2084.…

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NEJM This Week — June 5, 2025 24:10

2M ago24:10

24:10

Featuring articles on metabolic dysfunction–associated steatohepatitis, lung nodules, breast cancer, and improving birth outcomes; a review article on hemoglobinopathies; a Clinical Problem-Solving on from where it stems; and Perspectives on U.S. research leadership at a crossroads, on health care in an evolving immigration landscape, and on carryi…

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#178 Continuous Glucose Monitor (CGM): 5 Pearls Segment 33:34

2M ago33:34

33:34

🔹What are clinically relevant limitations of an A1c vs. a CGM (1:40) 🔹What do the different parts of the ambulatory glucose profile tell you? (09:59) 🔹What are common pitfalls, medications, lifestyle patterns that are important to ask your patient about when seeing them for a visit to manage blood sugar? (15:19) 🔹 How can you titrate insulin based …

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NEJM Interview: Zirui Song on the rise of concierge and direct primary care practices in the United States. 13:12

2M ago13:12

13:12

Zirui Song is an associate professor of health care policy and medicine at Harvard Medical School and a general internist at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. Z. Song and J.M. Zhu. Primary Care — From Common Good to Free-Market Commodity. N Engl J Med 2025;392:1977-1…