Best NguyenInDoubt Podcasts (2025)

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E19 - Gray Matter Shenanigans: What Really Happens in a Bipolar Brain 🧠 16:00

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11h ago16:00

16:00

Want to let us know something or ask a question? Send us a text! In this episode of The Y in Psychiatry, Dr. Amayo, Dr. V (Handratta), and Dr. Nguyen go full-neuroscience mode to unpack the neurochemistry and brain circuitry behind bipolar disorder — from dopamine/serotonin tug-of-wars to the roles of the prefrontal cortex, amygdala, and motor path…

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E17 - Ticket to Ride: The Bipolar Comorbidity Express Explored 20:03

2d ago20:03

20:03

Want to let us know something or ask a question? Send us a text! We hop aboard the Bipolar Express to unpack one of the messiest puzzles in psych: why diagnosing Bipolar Disorder sometimes feels like trying to solve a Rubik’s cube — when there could also be ADHD, anxiety, personality disorders, substance use, sleep-issues, or even childhood trauma …

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E16 – The B in Bipolar Stands for ‘Be Careful’: Diagnosing Bipolar Spectrum Disorders 23:53

6M ago23:53

23:53

Want to let us know something or ask a question? Send us a text! Our crew reunites to unpack one of the most enigmatic diagnoses in mental health: Bipolar Disorder. Join Dr. Amayo, Dr. Nguyen, Dr. Handratta, and freshly minted PGY-1 Edmund as they peel back the layers on: What bipolar disorder really is (spoiler: it’s not just mood swings) Why bipo…

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E15 - Late Life Depression: When the Golden Years Turn Grey (and the SSRIs Don't Shine) 18:55

8M ago18:55

18:55

Want to let us know something or ask a question? Send us a text! We close with a deep dive into late-life depression, where we explore why growing older can sometimes mean growing sadder. Dr. Handratta and Dr. Amayo uncover the four key culprits: executive dysfunction (DED, not a good acronym!), vascular woes, inflammatory fires, and amyloid beta b…

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E14 - Liver and Let Die: Navigating Antidepressant Use in Cirrhosis 18:49

8M ago18:49

18:49

Want to let us know something or ask a question? Send us a text! In this enlightening episode, the squad unravels the intricate tango between the liver and psychiatric medications, focusing on patients with cirrhosis. Discussing 1st-pass metabolism, phase 1 and 2 metabolisms, plasma protein binding, fluid overload, and the implications of these pro…

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E13 - Kidneys don't Kid Around with Antidepressants 13:54

2y ago13:54

13:54

Want to let us know something or ask a question? Send us a text! In this episode, Dr. Handratta and Dr. Amayo explore the importance of the kidney in psychiatry and discuss the impact of renal disease on medication management. They provide insights on dosing adjustments for various medications and highlight the role of the kidney in drug excretion.…

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E12 - Don't Forget About the Neurocognitively Impaired Populations 14:26

2y ago14:26

14:26

Want to let us know something or ask a question? Send us a text! Explore the intersection of depression and neurocognitive disorders in elderly patients. The discussion highlights the challenges in differentiating between depression and apathy, the importance of accurate diagnosis, and the appropriate pharmacological considerations for treatment. J…

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E11 - Even More Potentially Impotent Side Effects from the Antidepressants - Part 2 12:25

2y ago12:25

12:25

Want to let us know something or ask a question? Send us a text! Join Dr. Amayo and Dr. Handratta as they dive into the dark yet enlightening side effects of conventional antidepressants. From weight gain to sexual side effects and hyponatremia, this lively conversation unpacks the mechanisms, challenges, and potential solutions. Get ready for a do…

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E10 - Potentially Potent Side Effects of the SSRIs 11:57

2y ago11:57

11:57

Want to let us know something or ask a question? Send us a text! In this episode of The Y in Psychiatry, Dr. Amayo and Dr. Handratta explore the potentially potent side effects of SSRIs (selective serotonin reuptake inhibitors). They discuss the risks of switching to mania, the role of mood stabilizers, the increased risk of suicidality in younger …

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E9 - Depression - When All Else Doesn't Work 16:25

2y ago16:25

16:25

Want to let us know something or ask a question? Send us a text! When the algorithm for treating depression begin to have more branch point than words hinting at what to do next, we'll come to your aid with this podcast. Tune in as we briefly review the treatments reserved for the refractive cases. https://www.nguyenindoubt.com/theyinpsych https://…

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E8 - Depression - Continuing the Serotonin Soiree: Fluoxetine and Fluvoxamine 16:08

2y ago16:08

16:08

Want to let us know something or ask a question? Send us a text! Join us this evening for a soiree that will give Bridgerton a run for its money. But not really cause it'll be jiving to the conversation of fluoxetine and fluvoxamine: the twins of SSRIs that never were. Got that warm beverage ready yet for this episode? Good. https://www.nguyenindou…

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E6 - Depression - First Steps - Talk about it. 16:12

2y ago16:12

16:12

Want to let us know something or ask a question? Send us a text! Join us on a journey of hope and healing as we delve into the world of nonpharmacologic treatment options for depression. In this insightful podcast, we explore holistic approaches, therapies, and lifestyle changes that offer powerful tools for managing and overcoming depression. Our …

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E7 - Depression - Second Steps - Psychopharmacology Options with SSRIs 18:11

2y ago18:11

18:11

Want to let us know something or ask a question? Send us a text! Review with us the first line agents when considering psychopharmacology for your patients. The granular details can be daunting sometimes, but at the very least they'll help you be aware of some cautionary contexts, build your psychopharm database for that next test, or just flex whe…

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E5 - Depression Decisions: To SSRI or SNRI, that is the question... sometimes 13:04

2+ y ago13:04

13:04

Want to let us know something or ask a question? Send us a text! Come learn about the do’s and don’ts of depression. In this episode, Dr. Miracle and Dr. Hendratta deep dive into depression. They discuss everything from why we need to treat it, how to diagnose it, and its different treatment modalities. Whether you are a seasoned psychiatrist who t…

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E4 - Very Vivacious Vortioxetine 14:37

2+ y ago14:37

14:37

Want to let us know something or ask a question? Send us a text! Join our journey through a landscape of vortioxetine via neurotransmitters, GABA interneurons, and serotonin receptors, all with the audacious goal of making this complex antidepressant understandable. The hosts' heavy accents might challenge your ears, but their insights will stimula…

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E3 - Special K Bar: Granular Granule Neurons and Ketamine 14:33

2+ y ago14:33

14:33

Want to let us know something or ask a question? Send us a text! On this episode, we will continue our antidepressant journey and find out what the buzz around ketamine is all about. Hear Dr. Miracle and Dr. Hendratta discuss the use of ketamine in the treatment of depression. Explore everything from its receptors in the brain, why it works so fast…

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E2 - The Enigmatic Enigma: Decoding the Mechanisms of Antidepressants 10:50

2+ y ago10:50

10:50

Want to let us know something or ask a question? Send us a text! This episode embarks on an intriguing journey into the mysterious world of antidepressants. In this episode, we unravel the mysteries surrounding these medications, delving into how they work in the brain and why they can take time to have an effect. Discover the hidden mechanisms and…

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Trailer 2: What are we four? 2:39

2+ y ago2:39

2:39

Want to let us know something or ask a question? Send us a text! We heard your feedback and decided to introduce another trailer with a little bit more background on the hosts behind the podcast. Be sure to check it out and give us some kudos, or hopefully some constructive feedback. https://www.nguyenindoubt.com/theyinpsych https://feeds.buzzsprou…

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E1 - Bridging the Mood Gap: A Neuro-Tour of the Major Brain Networks 13:36

2+ y ago13:36

13:36

Want to let us know something or ask a question? Send us a text! Hold tight as we take a whirlwind tour into the moody labyrinth of depression on "The Y in Psychiatry" express, with Dr. H and Miracle in the driver's seat. This is not your typical clinical field trip - it's a rollercoaster ride through brain inheritance battles, childhood monsters, …

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Trailer 1: Yes, a palatable way to digest neuropsychopharm 2:19

2+ y ago2:19

2:19

Want to let us know something or ask a question? Send us a text! A sneak peek into our podcast on neuropsychopharm, coming to headphones near you in summer of 2023. https://www.nguyenindoubt.com/theyinpsych https://feeds.buzzsprout.com/2185312.rssBy NguyenInDoubt