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Every Possible Angle

Paragonix Technologies

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Explore the fascinating world of organ transplantation through the eyes of seasoned industry professionals as they share insights, experiences, and the latest advancements in the field. Hosted by Paragonix Technologies.
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Do you know how organs are traditionally transported for transplantation purposes? In a cooler filled with ice. When I learned that this approach was the most widespread method, I admit I was quite shocked... We talk here about "living" organs whose preservation is crucial for the success of their transplant! And as you can imagine, these transplan…
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In this episode of "Every Possible Angle," we interview Dr. Jeffrey Teuteberg, the section chief of heart failure, cardiac transplantation, and mechanical circulatory support at Stanford Medicine. Dr. Teuteberg shares his journey into the field of heart transplantation, discussing his early interest in medicine, his educational path, and his eventu…
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While studies have yet to prove a direct causal link, the correlation between smartphone use and declining mental health is well-established, a trend especially concerning among young people. But what if the same technology contributing to the problem could also be the solution? It turns out the therapeutic potential of our smartphones for mental h…
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Is there a future where we will manufacture entire organs? If that's the case, it’s not tomorrow. Yet, the era of regenerative medicine and tissue engineering is very much real and happening now! In some fields, like in dentistry, we are already 3D printing implants that are placed in patients' mouths. In others, like in orthopedic or plastic surge…
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Is there a simple way to know your hydration level? Not really. It's a surprising reality, considering our bodies are composed of roughly 60% water. When you consider that half of all people drink less than recommended and that chronic dehydration leads to an increased risk of chronic diseases and premature mortality, it becomes clear that monitori…
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Three years after the 2022 "crypto winter" severely damaged public confidence in these technologies (even among healthcare leaders), the term Web3 is conspicuously absent from the current healthtech space. So, what happened? And where do we really stand with the adoption of these technologies within our healthcare systems? Anca Petre is perfectly p…
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What's the link between quantum physics, AI, and drug discovery? Maximilien Levesque might be the perfect person to answer. A former theoretical physicist, he realised his research could transform drug development by fundamentally understanding how molecules interact at the atomic level. In 2019, he co-founded Aqemia with Emmanuelle Martiano Rollan…
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Meet Chris, the "Cardiac Kid." Chris was kind enough to join us in the studio and share his patient journey through multiple heart transplants - from his initial diagnosis of dilated cardiomyopathy with PJRT syndrome, to his first heart transplant at age 17, to the discovery that another transplant would be needed. He reflects on the challenges and…
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Can we learn from extreme cancer survivors to develop new treatments? This is the bet that Nicolas Wolikow and his team at Cure51 are making. Backed by the world's top cancer centers and specialists, they work around the clock to build the largest-ever health dataset of patients who defied the odds—people diagnosed with stage 4 cancer who were give…
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In this episode of Every Possible Angle, we sit down with Dr. Kiran Dhanireddy to explore “Path to Progress: Abdominal Innovations and Impacts.” Dr. Dhanireddy discusses the latest advancements in abdominal transplant techniques, sharing insights on how innovation is improving patient outcomes and shaping the future of transplant care. Listeners wi…
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Disclaimer: Blythe and I both work for Roche; nevertheless, all opinions expressed in this episode are our own and do not necessarily represent the position of our employer. What's really behind the term "real-world data" in clinical science? And what can it actually be used for? I asked Blythe Adamson of Flatiron Health to find out the answer. It …
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How can we solve the puzzle of regulating AI in healthcare? This is the question that Dr. Ricardo Baptista Leite and his team at HealthAI - The Global Agency for Responsible AI in Health ask themselves every day. Their goal? To help international organizations, governments, and local stakeholders strike a balance between regulation and access to th…
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In this episode of Every Possible Angle, we hear from Dr. Brittany Clayborne, a heart transplant recipient whose son Micah has also received a life-saving heart transplant. They share their deeply personal journey of hope, perseverance, and the emotional highs and lows of living with and receiving a donor heart. Their story is a powerful testament …
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When we think of the term "medicine," one of the symbols that comes to mind is the stethoscope. Its use in almost every physical examination by healthcare providers makes it one of the most iconic and widely recognized medical devices. Despite the emergence of digital technologies and the first electronic stethoscopes, their operating principle and…
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Do you have to come close to death to invent a groundbreaking medical device? That’s certainly not something we would wish upon every medtech entrepreneur. But it is the story of Shavini Fernando and the connected earring OxiWear that she developed. Shavini lives with Eisenmenger syndrome, a condition where the two ventricles of her heart communica…
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In this episode, we’re joined by Nathan Fine, Organ Utilization Manager of the Donor Network of Arizona, an Organ Procurement Organization (OPO) known for its trailblazing efforts in expanding access to lifesaving transplants. Nathan takes us behind the scenes of their innovative practices, including their adoption of Paragonix preservation devices…
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Dr. Gabriel Schnickel discusses his journey into transplant surgery, the intricacies of liver transplantation, and the collaborative nature of the field. The conversation highlights the newly established REIMAGINE Center, aimed at transforming organ donation and allocation processes to save more lives. The discussion also highlights upcoming educat…
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Lynda Lee Smith, CEO of Enduring Hearts, joins us to discuss their mission to improve pediatric heart transplantation through research and collaboration. Lynda shares her journey into the field, the founding story of Enduring Hearts, and the significant impact of their research initiatives. The conversation highlights the importance of collaboratio…
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In this episode, Dr. Alin Gragossian shares her unique journey as a physician and a heart transplant recipient. She discusses her early interest in medicine, the challenges she faced during her medical training, and the unexpected heart failure that changed her life. Dr. Gragossian reflects on her recovery process, the emotional struggles post-tran…
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In this episode of Every Possible Angle, Dr. Gary Schwartz, the Chief of Thoracic Surgery at Baylor University Medical Center, shares his journey into the field of transplantation, the evolution of lung transplantation practices, and the impact of new technologies like ECMO and BAROguard. He discusses the challenges faced in organ recovery and the …
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Sharon Klarman, the Executive Director of Solid Organ Transplant at Tufts Medicine, is entirely dedicated to driving advancements in transplantation and enhancing patient outcomes. Her interest in program development and harnessing efficiencies has allowed her team to go above and beyond to meet their community's needs. Thanks for listening! Sittin…
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Joining us in the studio this week is Dr. Eugene Golts, an esteemed cardiothoracic surgeon who performs the full scope of cardiothoracic surgery and thoracic organ transplantation. Dr. Golts is surgical director of the Lung Transplant Program at UC San Diego Health. He joins us to discuss the shifting landscape in the field, and the pressures of lu…
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In an exclusive episode, we're joined by President and Founder of Paragonix Technologies, Dr. Lisa Anderson, to celebrate the milestones of 2024 and the promising future of 2025. Having just celebrated the incredible achievement of transporting over 10,000 donor organs in total, we set our sights on the aspiring goal of transporting another 10,000 …
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In this episode, Dr. Rajat Walia and Dr. Michael Smith of the Norton Thoracic Institute join the studio to discuss the changing complexities of thoracic transplantation. Recent advances and new innovations have shown great potential to impact critical factors for many parties involved. Thanks for listening! Sitting down to watch? Find the episodes …
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One of the greatest fantasies in medicine is to one day be able to offer any patient a therapy perfectly adapted to their profile and needs. A "personalized" medicine. The term was introduced to the public in 1999 through an article in The Wall Street Journal titled "New Era of Personalized Medicine: Targeting Drugs for Each Unique Genetic Profile.…
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According to the WHO, unsafe medication practices and medication errors are a leading cause of avoidable harm in health systems across the globe. In the European Union alone, this translates to nearly 200,000 deaths annually. The magnitude of this problem has led to global initiatives such as "Medication Without Harm," launched in 2017, aiming to r…
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What will the future of surgery look like? According to Dr. George Papagiannakis, we must count on virtual simulation. After all, simulators are an integral part of professional training in highly demanding fields like aviation or F1. So why not medicine? The approach might seem futuristic, but George and his team at ORamaVR share a vision that mak…
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Our gut contains a world of microorganisms that impact many aspects of our health, well beyond the gastrointestinal system. In fact, more than 30 trillion bacteria, archaea, fungi, and viruses live in the digestive tract of every human, a number that is higher than the number of human cells that make up our body! Each microbiome is unique to an ind…
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All experts agree: if there's one sector that AI will transform, it's healthcare. Whether it's understanding pathologies, developing personalized treatments, the doctor-patient relationship, diagnostic methods, or creating tools to facilitate the work of healthcare professionals, everything is affected by the ongoing transformation! This revolution…
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In this episode, Tara Storch, co-founder of Taylor's Gift Foundation, shares her family's journey through tragedy and the creation of a foundation dedicated to organ donation awareness and grief support for donor families. Tara recounts the story of her daughter Taylor, who became an organ donor after a tragic accident, and how this experience led …
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Among pioneering companies in connected health devices, few have been as forward-thinking as Withings, a flagship of French technology. Their first connected scales date back to 2009 (when smartphones were still emerging!) and remain the industry standard today. For that time, it was a subtle blend combining sleek design, intuitive user experience,…
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Medical biology and laboratories play an essential role in any health system. No wonder 70 to 80% of all medical decisions are based on laboratory test results. But even within the most advanced healthcare systems, the communication and analysis of lab data remain archaic. Processing times can be lengthy, even after the analysis is completed. Resul…
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