Forecasting and prediction tools are missing links in DeFi and Mode Network is trying to fill that gap. In this episode, James Ross (co-founder of Mode and Synthdata) talks about building smarter forecasting systems for DeFi. We dig into how Mode is using BitTensor’s decentralised AI network to power real-time risk analysis, how agents could drive …

Stablecoins are crypto’s biggest product-market fit—$230B and growing. But the pipes that move them? Broken. In this episode, Saurabh speaks with Jay Kurahashi-Sofue (CMO) and Ryne Sachs (CEO) of Eco, who are building something surprisingly rare in crypto: infrastructure that actually works. Not another stablecoin—but a liquidity layer that coordin…

From regulatory battles that forced him out of DeFi, to the conviction that drew him back, Andre opens up about the unseen cost of innovation in a space that now rewards safety over experimentation. This isn’t a retrospective of Yearn or a breakdown of his past projects. It’s a look at why composability collapsed, how decentralisation became a UX b…

Recorded just before the market was hit by tariff chaos, this episode captures a rare quiet moment—and uses it to unpack the deeper mechanics of how crypto actually works. From the Hyperliquid–JELLY saga to the evolving reality of intents, solvers, and Ethereum’s fragmentation, Jose brings sharp, grounded perspective without the fluff. This isn’t a…

In this episode, Ejaaz joins Saurabh to explore what it really takes to build usable, decentralized AI tools on crypto rails. We break down the AI x Crypto stack from first principles: – Why fragmented compute networks haven’t worked (and what might change that) – How AI agents are reshaping crypto UX – Why open-sourcing everything could backfire i…

We break down why the familiar crypto playbook no longer applies. We explore the death of predictable Bitcoin cycles, how macroeconomic shifts under Trump's administration are reshaping markets, and why stablecoins like USDC could soon dominate finance. Will shares his disciplined strategy—separating long-term conviction from short-term trades—and …

In a space where information is the ultimate edge, how do the best traders and builders stay ahead? Shaw from elizaOS returns to the podcast to break down the harsh realities of crypto trading, AI-driven investing, and building through market cycles. We explore: •The information edge in crypto: Why the best traders aren’t chart readers but those cl…

We discuss Jai's journey from leading blockchain integration at Coinbase to founding DefinitiveFi, and how the platform grew from $20-30M to nine-figure monthly volumes. Jai explains the key innovations needed for mainstream DeFi adoption - gas abstraction, chain abstraction, and account abstraction - and how advanced order types like TWAPs allow l…

Ethereum scaling has been an uphill battle. We’ve built rollups, fragmented liquidity, and pushed execution limits—but have we really solved the problem? Instead of patching Ethereum’s existing framework, MegaETH has rewritten the Ethereum data structure from scratch, eliminating bottlenecks and achieving millisecond block times. The implications? …

Bitcoin mining is a delicate balance between mathematical certainty and real-world volatility. In this episode, Nick Hansen, CEO of Luxor, breaks down the evolution of mining—from hardware cycles to energy markets, hashrate futures, and Bitcoin’s shrinking block subsidy. We also discuss miners' role in stabilising power grids and the contentious de…

Web3 marketing has a retention problem. Too many projects chase mindshare, but few know how to build communities that last. In this episode, Phin, lead marketer at Abstract, shares his journey from Web2 to Web3 and unpacks why most crypto marketing playbooks are fundamentally flawed. We explore why engagement farming isn’t enough, why crypto produc…

In this episode, Yannik Schrade, CEO of Arcium, explains how they're building an encrypted supercomputer to bring privacy to both Web2 and Web3. We explore: • The journey from creating one of the world's most downloaded iPad apps to building privacy infrastructure • Why current privacy solutions like trusted hardware and zero-knowledge proofs aren'…

What if the popular belief that Bitcoin is "digital gold" is holding crypto back? Kyle Samani, Managing Partner at Multicoin Capital, unpacks why this analogy might be misleading and argues that utility—not nostalgia—will define the future of digital assets. We trace Multicoin’s evolution, from its early experiments to backing Solana when it was di…

Shaw's journey from mixing bands in NYC clubs to creating AI16Z reflects the unexpected ways innovation emerges in crypto. What began as a way to help developers access better trading strategies has evolved into an AI-driven DAO managing $21M in treasury funds, with their agent "AI Marc" making investment decisions by evaluating community members' …

Brandon Kumar of Layer3 joined us for a founder series. Who better than a founder to ask fellow operators what it takes to build companies? This is episode one of many to come. Let’s go. Running a successful crypto company takes more than technical know-how; it requires understanding the human elements that bring an organisation to life. In the fir…

Fed up with missed opportunities because your crypto is scattered across different chains? In this episode, Vaibhav Chellani, co-founder of Socket, shares his vision for a future where blockchain fragmentation is no longer a barrier. From pioneering ZK rollups before they were mainstream to building Socket, Vaibhav tackles the big issues facing cry…

Larry Cermak, CEO of The Block, joined us for a frank conversation about crypto's evolution. He played around with BTC to buy NBA accounts to watch basketball and got hooked on understanding how it all worked. Later, he turned down Binance and missed ~300x gains on BNB. Fast forward to 2023, and he was handling layoffs and M&A as the CEO of the lea…

Fresh from hitting $18M in daily volume, Chainflip CEO Simon Harman delivers a masterclass in building crypto infrastructure. In this raw, technical conversation, he dismantles popular narratives around Bitcoin L2s and reveals what it actually takes to move BTC across chains. After spending 4 years solving complex cryptographic challenges while oth…

Mika Honkasalo's path from basketball analytics to crypto is anything but ordinary. During DeFi summer, his liquidity mining calculator became a yield farmer's essential tool, kickstarting his deep dive into DeFi's intricacies. Our conversation revisits Mika's insights on Solana's transaction dynamics, sparking an Ethereum vs Solana debate. While E…

Sreeram Kannan from EigenLayer joins us to discuss the evolution of human coordination mechanisms and the role blockchains play in their transformation. In this first episode since the token’s release, he discusses what attracted him to the industry, the challenges in bootstrapping trust and how AVSs play a role within it. According to Sreeram, soc…

In this episode of the DCO Podcast, we sit down with Arthur Cheong, founder of Defiance Capital. We explore the concept explore the contrast between liquid and venture investments in crypto. With venture capitalists fiercely competing for private deals and driving up valuations before projects go public, the less crowded liquid markets often offer …

Before we begin…Sid and I are sorting out our schedules for Token2049 in Singapore. I’ll also be on a panel at Breakpoint. We’re excited to connect with researchers and founders working on the cutting edge. If you’re around, respond to this email and drop us a line. We’d love to meet up in person. Joel Hello! In this episode of the DCO Podcast, Ran…

In this episode, Pacman, founder of Blur and Blast, explores the evolution of NFT marketplaces and Layer 2 solutions in crypto. He begins by reflecting on his startup journey, including his early days at Teespring and launching Namebase. Pacman shares how Blur, launched in 2022, quickly rose to prominence by catering to high-volume traders. It fill…

Hello! In the latest episode, we dive deep into the mind of Tomasz Tunguz. He is a venture capitalist who’s been in the game for over 15 years. As a General Partner at Theory Ventures and former Managing Director at Redpoint Ventures, Tomasz has witnessed the evolution of venture capital firsthand. From his early days at Google trying to monetise s…

We are joined by Matt Luongo from Thesis for today’s issue. Thesis is a Bitcoin oriented venture studio that is behind the likes of Fold, Acre and tBTC. Our episode, recorded last week, is an unfiltered look into the world of Bitcoin from someone who’s seen it all from the ground up. We explore the projects that Matt’s team at Thesis is spearheadin…

Before we begin… Last week, we announced the launch of DCo.build. As our publication grew, it was time to create a single hub for founders looking to collaborate with us on advisory, distribution and go-to-market strategies. The newsletter will continue to be the place where we showcase our research. DCo.build, will be where we put it to practice t…

Robert Drost is the CEO of @eigenfoundation, research partner at Ethereal Ventures and the former head of R&D at ConsenSys. Prior to jumping into crypto, he was an accomplished engineer with a 159 patents to his name. Our conversation delves into▪ Parallels between Web2 and Web3 infrastructure development▪ Issues in Web2 that are the biggest opport…

Have you ever made an impulse purchase on Instagram? Our guest today may have a role to play in it. Antonio García Martínez was part of the team that helped Facebook build its ad engine. He is also the author of Chaos Monkeys—a beautiful memoir of how the startup ecosystem used to be in the early 2010s and what it took to survive it. He was also a …

Gin Chao from No Limit Holdings joins us today to draw parallels with the evolution of the web and the state of crypto. No Limit Holdings is a venture investment firm that was early to back the likes of Ethena (now valued at $7.5 Billion) and Wynd. Gin's journey into crypto started a decade back with a poker game involving CZ. Prior to starting No …

Today, we’re joined by Mike Silagadze, the CEO and founder of EtherFi. Before EtherFi, he was the founder and CEO of Top Hat, a dynamic courseware company for educators. He scaled that to over 500 employees and $60 million in revenue before switching his focus to crypto. Mike was also early to Bitcoin. His first Bitcoin purchase was at 80 cents in …

Today, we are joined by one of our portfolio founders, Prasanna Sankar. We have been huge fans and investors in what he has been building with 0xppl. The product helps users know what their friends are doing on-chain. Think of it as Facebook, but for user wallets. Prior to founding 0xppl, Prasanna was involved with building Rippling - a company cur…

Monad was in the news in April 2024 for raising a little over $225 million. As of publishing, it is the largest venture round round in crypto for the year. But what even justifies that amount of money going into a new network? Why is it even needed?Our latest episode is an hour long conversation with Keone Hon. Prior to building Monad, he spent a d…

How do you scale as an employee alongside a network that is on its way to a multi-billion dollar valuation? What does it take to go from being an intern to Head of Strategy at a network that has acquired some of the most talented people in Web3? Sankset Shah may have the answers. In today’s episode, he joins us to discuss his journey over the years…

Our guest for the episode is Austin Adams from Anagram . We discuss the reasons for Solana’s congestion, fixes that have already gone live, and other measures in the works that will further alleviate the problem. We also discuss the highly anticipated Firedancer client and the state of L2s on Solana. Austin also helps us keep up to speed on the dev…

Sunny Aggarwal from Osmosis labs joins us in this episode to discuss the emergence of L2s, meme-assets, and the future of shared security. Sunny was an early member of the team behind Cosmos and is currently a co-founder of Osmosis labs. He joins us to share how his career has evolved over the past three cycles, what he has learned along the way, a…

Today, we are joined by Vishwa from Anera Labs. From setting up a fund of funds to running a fintech company and using ChatGPT to enter crypto hackathons - this is a unique tale. One that captures the soul and spirit of crypto. He joins us today to explain the emerging market for intents and the role they would play for UX in the years to come. Alo…

Hello,We are joined by Arjun Chand from LiFi today to discuss all things bridges. They have grown into an ecosystem handling close to $20 billion today. As the number of blockchain ecosystems increase, bridges will become crucial infrastructure enabling the movement of money between them. LiFi is a dominant player facilitating SDKs for developers l…

Hey there, There’s too much information and too little time to process it. Being terminally online is the price you pay to stay on top of research from Substack, Twitter, Medium, Discord and Reddit. That is not a good way to build one’s life. Kaito helps reduce the noise and get’s you straight to what you need. The product parses information across…

We have a podcast and a long-form in this issue. First, we begin with a conversation with Anirudh Pandita from Loco.gg, one of India's leading game streaming platforms. We then go into a long-form written with an abundance of inputs from Ishan of Glip.gg. Tune in for insights on the evolution of the gaming landscape in India and the challenges with…

Hey there! I'll keep this one short. Decentralised.co's core mission has been to surface the best stories in Web3. We have been perfecting our stories with text as a medium for the past few months. You may have noticed us improving our visuals, expanding the breadth of topics and looking towards the niche, esoteric use cases very few writers cover.…