The a16z Podcast discusses tech and culture trends, news, and the future – especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This podcast is produced by Andreessen Horowitz (aka “a16z”), a Silicon Valley-based venture capital firm. Multiple episodes are released every week; visit a16z.com for more details and to sign up for our newsletters and other content as well!
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a16z Live is the place to listen to recorded live discussions and events featuring, hosted, or co-hosted by a16z partners (with outside voices too). As a reminder, all content posted here is provided for informational purposes only, and should not be relied upon as legal, business, investment, or tax advice. Views expressed are those of the individuals and not the views of Andreessen Horowitz, please see a16z.com/disclosures for more. To learn more about the broader a16z Podcast network and ...
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Web3 is going to eat software! I talk with minds behind truly innovative projects using blockchain technology to solve real-world problems so you can be ahead of the curve with your knowledge or business. Discover future Amazons, Googles, and AirBnBs of the world through the exciting personal journeys of their creators! I’ve been building and helping tech businesses since 2001. I know firsthand how important it is to constantly learn about what’s happening on the edges. How is your industry ...
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16 Minutes on the News is a short news podcast where we cover the top headlines of the week, the a16z podcast way -- why are these topics in the news; what's real, what's hype from our vantage point; and what are our experts' quick takes on these trends? About the a16z Podcast: Discusses tech and culture trends, news, and the future -- especially as ‘software eats the world’. It features industry experts, business leaders, and other interesting thinkers and voices from around the world. This ...
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If you're looking for another over-scripted and edited podcast, this is not it. But if you want to listen to honest and unfiltered discussions about the latest in tech and its impact on society, welcome, you have come to the right place. This is Another Podcast where two friends and colleagues discuss their overlapping experiences and perspectives on what happens in technology. We might know some of the same things, yet we also have different backgrounds and expertise, or at least, we ask di ...
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The Technium is a weekly podcast discussing the edge of technology and what we can build with it. Each week, Sri and Wil introduce a big idea in the future of computing and extrapolate the effect it will have on the world.
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“Software eats the world”, as one famous investor once said it. However, our Earth runs on resources and is based on atoms rather than bits. Our true progress therefore depends mainly on our producing, selling innovative physical products, that is hardware. Hardware is...different. Challenges abound in designing, manufacturing, getting funding, hiring, innovating, delivering to the customers. Resources are scattered around and only a few exist. Where do you get real, practical knowledge? Thi ...
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We scale and start amazing new ventures - Supercharging start-ups & entrepreneurs by unlocking the power of corporates. @thebakeryldn thebakery.com
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Gender diversity are buzz words these days– And paradoxically, this is a problem in the fields of science, technology, arts, humanities or medicine. A Hashtag #genderdiversity on social media is used for everything from issues like salary disparity, lack of women in a position of power, navigating career and motherhood to sexual harassment – These are definitely important issues to address. But the need for more women in science, humanities goes beyond issues of just equality and morals. Hi, ...
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What Comes After Mobile? Meta’s Andrew Bosworth on AI and Consumer Tech
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32:30Are we nearing the end of the smartphone era? In this episode, a16z Growth General Partner David George talks with Meta CTO Andrew “Boz” Bosworth about what comes after apps and touchscreens. From smart glasses to AR headsets, Boz shares how AI is powering a new wave of computing—one that’s ambient, agentic, and driven by human intent. They explore…
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What Comes After Mobile? Meta’s Andrew Bosworth on AI and Consumer Tech
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32:30For the past 20 years, consumer technology has been shaped by the same form factors: apps and touchscreens on smartphones. But advances in AI, wearables, and hardware could introduce an entirely new stack—creating a more agentic, adaptive, and immersive computing experience for users everywhere. Drawing on his early days building Facebook’s News Fe…
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Pop-Up Cities, ZK Tech & Living Forever — A Web3 Longevity Story with Francesca from AvinasiLabs
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55:22Summary What happens when ZK cryptographers, pop-up cities, and longevity scientists collide? In this special Web3Magic episode, I sit down with the one and only Francesca, a multidisciplinary personality bridging decentralized science, digital identity, and transhumanist visions of the future. Francesca returns to the pod after a whirlwind journey…
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Conviction Over Hype: Building Real Products in Web3 with Chinmay, Percs & Basket.farm
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45:05Summary What happens when a dev agency founder becomes a Web3 believer, builds tools for Fortune 500s, and ends up creating one of the most exciting products in Farcaster land? Find out in this candid and idea-packed episode with Chinmay, founder of Percs and Basket.Farm. We go deep on: - Chinmay’s journey from agency life to building in crypto - L…
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The Dual-Use Founder: Vets Now Building For America
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37:51In today’s world, the battlefield extends far beyond war zones—it’s embedded in our tech stacks, supply chains, and airspace security systems. So who better to solve these modern challenges than those who’ve served on the front lines? Recorded live at the third annual American Dynamism Summit in Washington D.C., this episode features a16z’s Matt Sh…
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TLDR - Why Is MINIMA The Most Decentralized Blockchain
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11:47What if your phone could run an entire blockchain — no miners, no middlemen, just pure freedom? In this 10-minute TLDR episode of Web3 Magic, Paddy from Minima drops an absolute masterclass on what true decentralization really means. We explore how Minima flips the script on traditional blockchain architecture with a protocol so light, it runs enti…
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Is Decentralized Science (DeSci) the biggest scientific shift since the internet with Andrew Hemingway
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42:00Summary In this episode, we sit down with Andrew Hemingway, founder of the DeSci Alliance, to explore how Web3 is transforming how science is funded, shared, and collaborated on - from breaking pharma’s data monopoly to onboarding citizen scientists from Reddit. Whether you're curious about DeSci, a startup founder in healthtech, or just want to un…
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War has always been shaped by technology—from steel and gunpowder to GPS and nuclear weapons. But the decisive technologies of tomorrow aren’t coming—they’re already here. In this episode, recorded live at our third annual American Dynamism Summit, a16z’s Senior National Security Advisor Matt Cronin sits down with Ryan Tseng (cofounder & CEO, Shiel…
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It's easy to say what tech companies want from AI, but much harder to talk about the product strategy - they're all pretty much the same. "Just build a better model!" Where does that go? Can they differentiate? What would it mean to differentiate a product that can do 'everything' - what would different everythings be?…
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How to Build with the Department of Defense
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51:18When people think about startups working with the government, the phrase “black box” often comes up. But what if that box is finally being pried open? In this episode—recorded live at the American Dynamism Summit in DC—we talk with two Chief Technology Officers at the heart of American defense: Alex Miller, CTO for the Chief of Staff of the Army, a…
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The Top 100 GenAI Products, Ranked and Explained
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38:14This month, a16z’s Consumer team released the fourth edition of the GenAI 100 — a data-driven ranking of the top 50 AI-first web products and mobile apps, based on unique monthly visits and active users. In just six months, the consumer AI landscape has shifted dramatically. Some products surged ahead, others plateaued, and a few unexpected players…
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Jensen Huang and Arthur Mensch on Winning the Global AI Race
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55:03The global race for AI leadership is no longer just about companies—it’s about nations. AI isn’t just computing infrastructure; it’s cultural infrastructure, economic strategy, and national security all rolled into one. In this episode, Jensen Huang, founder and CEO of NVIDIA, and Arthur Mensch, cofounder and CEO of Mistral, sit down to discuss sov…
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AI voice technology has been around for years — think Siri or Alexa — but the magic has been missing. That’s changing, and quickly! In this episode, Anish Acharya, General Partner at a16z, and Olivia Moore, Partner at a16z, explore why AI voice is reaching a breakthrough moment, how today’s models feel more human than ever, and why voice is poised …
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From Thesis to Meme to Fund: Building American Dynamism
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42:38For over a century, the United States has been the birthplace of world-changing innovation – from the Wright brothers’ first flight to the invention of the transistor, the moon landing, and the birth of the internet. But in recent years, belief in American progress has wavered. Three years ago, a16z General Partner Katherine Boyle wrote a bold thes…
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What Founders Get Wrong About Scaling – With Carta’s CEO
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40:37Henry Ward, cofounder and CEO of Carta, has spent over a decade scaling his company from an early-stage startup to a 2,000-person industry leader. In this a16z Speedrun conversation with Games partner Josh Lu, Henry shares hard-earned lessons on: Hiring missionaries vs. mercenaries — and how to keep company culture intact as you scale The reality o…
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The Future Backbone of Modern Finance is onchain: Swiss Franc Stablecoins and Bitcoin
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49:41Research suggests that there are only two crypto assets that can protect you from geopolitical risk - Swiss Franc (CHF) and Bitcoin (BTC). Now, you find both onchain for DeFi, thanks to Frankencoin. This is a conversation with Johannes (MD of Frankencoin Association), where we discuss the Swiss Franc stable coin called Frankencoin, its decentralize…
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Finding Real Connection Privately with Cupid AI and Soulmates - Amelia is building future of love finding
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41:01To find love you should not need to have public profile and swipe left/right like on the beauty market. Btw, there are many forms of love! In this conversation, I dive with Amelia her innovative project called Soulmates which is all about creating authentic connections through technology. We cover the unique framework of Soulmates, the role of AI i…
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In crypto speed to market and correct tokenization is everything - Konstantin from Mezen advising founders in Web3
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44:06PolitiFi, i.e. tokens or coins launched by political figures and celebrities are here to stay. At least we agreed on it with Konstantin from Mezen. In this conversation, we discuss the evolving landscape of Web3 with focus on tokenomics, the rise of celebrity tokens, and the importance of understanding business fundamentals in the crypto space. Kon…
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Trading memecoins is as easy as tapping Bolide app on your phone, talk with founder Oxana
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31:48Trading meme coins is where many retail users start their Web3 journey, outside of centralized exchanges like Coinbase. Today, I talk with Oxana, the founder of the Bolide app. Bolide is a meme coins trading supermarket in your pocket. We discuss (as always) her journey into the crypto world (spoiler: she was early!), previous projects, and how the…
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Creativity vs Control: Where AI Fits in the Creative Toolbox
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42:22Being a creator in 2025 is tough—but building for creators is even harder. Perhaps no one understands this conundrum better than Scott Belsky. As the founder of Behance, a longtime executive at Adobe, and an advisor to companies like Pinterest and Atlassian, Scott has spent his career at the intersection of technology, design, and creativity. In th…
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Set the right Fitness Goals in 2025, chat with the fitness coach Alyna
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41:01We talk about the importance of setting realistic and measurable fitness goals for 2025 and explore the common pitfalls of unrealistic expectations. Chose performance-based goals over aesthetic ones. I talk with Alyna Han, a multi-talented personal fitness coach about the importance of understanding one's needs and emphasizes the significance of ha…
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Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto
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32:55Technology doesn’t grow in isolation—it evolves in waves. Just as mobile, cloud, and social shaped the internet of the past 20 years, so too could crypto, AI, and new hardware usher in an era of the internet that’s pro-innovation, pro-startup, and pro-creator. Speaking with a16z Growth General Partner David George, a16z crypto Founder and Managing …
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Who Will Own the Internet? a16z’s Chris Dixon on AI and Crypto
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32:55Technology doesn’t grow in isolation—it evolves in waves. Just as mobile, cloud, and SaaS shaped the internet of the past 20 years, so too could crypto, AI, and new hardware usher in an era of the internet that’s pro-innovation, pro-startup, and pro-creator. Speaking with a16z Growth General Partner David George, a16z crypto Founder and Managing Pa…
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How AI Is Changing Warfare, with Anduril CEO Brian Schimpf
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35:22Anduril reimagined how startups can build software and hardware for the defense sector. Now, they're using AI to reimagine modern warfare. Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf discusses how AI helps humans make better strategic decisions by sorting through the enormous amount of data collec…
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The Critical Technology in Finding Critical Materials
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42:38Critical materials like copper, lithium, and gallium have been mined for decades, but their role in core technologies, geopolitics, and the energy transition have come to a height in recent years. In this episode, a16z partner Connie Chan discusses how technology is changing the game of identification and exploration, together with leading company …
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DeepSeek: America’s Sputnik Moment for AI?
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43:03Two words have caught the Internet by storm. DeepSeek. The Chinese reasoning model r1 is rivaling others at the frontier with an open-source MIT license, methods that some claim may be 45x more efficient, an alleged $5.6m cost, the release of reasoning traces, a follow-on image model, and the fact that all of this was released by a hedge fund China…
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In The Vault: How AI is Powering Payments with Greg Ulrich
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29:15
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29:15How does a company as massive as Mastercard decide where to deploy AI? Instead of centralizing every AI initiative, Mastercard operates under a “hub and spoke” model — balancing centralized AI leadership with decentralized innovation across business units. In this episode, a16z Partner Marc Andrusko chats with Mastercard’s Chief AI and Data Officer…
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Ben Horowitz Sharing History with Dr. Clarence Jones, MLK's Speechwriter
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55:45This week, a16z cofounder Ben Horowitz had a rare and invaluable conversation with Dr. Clarence B. Jones, a pivotal figure in American history. Dr. Jones, who served as speechwriter, attorney, and advisor to Dr. Martin Luther King Jr., shared his personal insights on race, inclusion, and the lasting legacy of the civil rights movement in 2025. In t…
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How AI Is Changing Warfare with Brian Schimpf, CEO of Anduril
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35:22How is AI reshaping modern warfare? Speaking with a16z Growth General Partner David George, Anduril cofounder and CEO Brian Schimpf discusses how AI helps humans make better strategic decisions by sorting through the enormous amount of data collected from modern battlefields. Schimpf also discusses navigating the US government’s complex procurement…
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Intelligent automation is transforming industries by tackling messy, unstructured workflows that traditional Robotic Process Automation (RPA) couldn’t handle. In this episode, a16z partner Kimberly Tan discusses the shift from rigid RPA systems to AI-powered agents and why this evolution unlocks massive opportunities in legacy markets. Drawing on h…
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Marc Andreessen: Can Tech Finally Fix Healthcare?
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32:33Healthcare is a $4 trillion industry, making up nearly a fifth of the U.S. economy—but despite having some of the best doctors and advanced technology, the system often delivers poor outcomes at skyrocketing costs. Why is this the case, and what will it take to fix it? In this episode, a16z cofounder Marc Andreessen and General Partners Vijay Pande…
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Building Substack: Reinventing Culture through Subscriptions
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36:45In this episode, Substack cofounder and CEO Chris Best joins a16z General Partner Andrew Chen to discuss the origins and evolution of Substack, a platform redefining media and empowering creators to connect directly with their audiences. They dive into how Substack’s early days led to over 3 million paid subscribers, why creators are moving away fr…
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Crypto Trends for 2025: Stablecoins, App Stores, UX, and More
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34:54with @sambroner @meigga @darenmatsuoka @jneu_net @chrislyons and @rhhackett @smc90 Welcome to our special end-of-year episodes -- which also look ahead to 2025 -- covering our annual Big Ideas lists, where various a16z crypto team members share what they are personally excited about. (You can see the firmwide list, also including all the trends of …
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Super Staffing Healthcare, Codifying Compliance, & Scaling Services
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52:09
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52:09As we prepare to step into 2025, the possibilities for applied AI are reshaping industries in profound ways. In this episode, a16z General Partners Julie Yoo and Angela Strange, and Partner Joe Schmidt, dive into the transformative power of AI across healthcare, fintech, and traditional service sectors. We explore: Super Staffing for Healthcare: Ho…
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The Race for AI—Search, National Infrastructure, & On-Device AI
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42:45The AI race is on, and 2025 could be its most transformative year yet. In this episode, a16z General Partners Anjney Midha and Jennifer Li, and Partner Alex Immerman dive into the trends reshaping AI and its impact on search, infrastructure, and devices. We explore: How AI-native tools like ChatGPT and Perplexity are challenging Google’s search dom…
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Jobs of the Future, Harnessing Earth Observation, & Gaming Tech Advances
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41:59As 2025 begins, industries are evolving at unprecedented speed: robots are revolutionizing manufacturing, terabytes of earth observation data are driving new possibilities, and gaming technology is transforming how we design, train, and innovate across sectors. In this episode, a16z General Partner Erin Price-Wright, Engineering Fellow Millen Anand…
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How Jack Henry is Modernizing Banking Infrastructure
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26:38Most financial institutions still bank on software built before the internet, but Jack Henry's CTO, Ben Metz, is leading a quiet revolution to change that. Speaking with a16z General Partner Angela Strange, Metz shares how banks’ historical tech infrastructure and regulatory obstacles have stymied innovation—and how Jack Henry is helping them overc…
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Scaling Shopify: Tobias Lütke and Ben Horowitz on Building a Global Giant
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45:26In this episode of Web3 with a16z, Shopify CEO and cofounder Tobias Lütke joins a16z cofounder Ben Horowitz for a conversation recorded live at the a16z crypto Founders Summit. Together, they explore what it takes to build a breakout startup in a competitive market, the changing landscape of retail, and how to drive workplace change while navigatin…
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Building a $20B+ Open Source Business with MongoDB's Eliot Horowitz
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40:16a16z Partner Seema Amble talks with MongoDB and Viam co-founder Eliot Horowitz about building sustainable open source software tools. From challenging Oracle to building the de facto cloud-based database management tool, Horowitz outlines MongoDB’s early go-to-market strategies, approach to community building, and enterprise sales motion. This epis…
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Did you know the U.S. nurse labor market is over $600 billion annually, but the dedicated software market for nurses is almost zero? In this episode General Partners Alex Rampell, David Haber, and Angela Strange discuss how AI is revolutionizing labor by automating tasks traditionally done by humans. They’ll trace the evolution of cloud eras — from…
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How Zapier Became Profitable in 3 years and Scaled to $5B with Wade Foster
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31:59a16z Partner Seema Amble connects with Zapier co-founder Wade Foster about the company’s founding and GTM success utilizing a product-led growth (PLG) strategy. Chock-full of actionable insights, this episode explores Zapier’s product strategy, customer experience, and how the team built a sustainable growth engine that enabled them to reach profit…
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For the past decade, Benedict has given an annual presentation on the state of technology, and he did the latest at Slush in Helsinki last month. In this episode we discuss some of the challenges and issues that he tried to cover. You can find the full presentation here - https://www.ben-evans.com/presentations…
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Fixing Education in America: What's Stopping Us?
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38:54Over half of Americans live in childcare deserts, while 90% of brain development happens before the age of five. All the while, education and childcare remain among the most resistant sectors to technological change. Billions of dollars have been spent, but outcomes continue to lag. Why? In this episode, we dive into the systemic issues—misaligned …
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How Gusto Used Customer Input to Scale Growth with Tomer London
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30:34In this episode, a16z Partner Seema Amble chats with Tomer London, co-founder of Gusto, about establishing product-market fit and product discovery. London shares how Gusto, now valued at ~$10 billion with 300,000+ customers, identified early customers who could provide valuable feedback that helped the team optimize the self-service product experi…
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This episode was originally published on our sister podcast, web3 with a16z. If you’re excited about the next generation of the internet, check out the show: https://link.chtbl.com/hrr_h-XC We've heard a lot about the premise and the promise of prediction markets for a long time, but they finally hit the main stage with the most recent election. So…
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Death of a Salesforce: Why AI Will Transform Sales
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16:34Sales is evolving. AI-native systems are replacing traditional CRM tools, capturing unstructured insights from emails, Slack, surveys, and more in real time. These systems automate early-stage tasks like prospecting and qualification, enabling sales teams to focus on high-value work—while AI provides live coaching and drives decisions across sales,…
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The Longevity Imperative: Redefining the Way We Age
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40:30What if the biggest challenge of our time isn’t living longer, but living better? In this episode, we’re tackling one of humanity’s greatest accomplishments—and perhaps its most overlooked challenge: longevity. As more people live past 100, our systems—healthcare, finance, career planning, and even our cultural perceptions of aging—need a fundament…
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America is a country of immense wealth, but our manufacturing infrastructure is struggling to keep pace. In this episode, we discuss the overlooked crisis of American manufacturing and what it means for our national resilience. a16z’s Oliver Hsu hosts a conversation with founders Jordan Black (Senra Systems), Chris Power (Hadrian), and Bryon Hargis…
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2024 has been a milestone year for autonomous tech. Waymo’s fully autonomous driver has surpassed 20 million miles, while FAA approvals now allow commercial drones to fly without visual observers, advancing air autonomy in unprecedented ways. In this special live recording from SF Tech Week, a16z partner Erin Price-Wright moderates a panel of exper…
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How to Build a Thriving AI Ecosystem with Lisa Su, CEO of AMD
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37:07High-performance compute is the bedrock of generative AI, and if there’s anyone who knows about high-performance chips, it’s AMD CEO Lisa Su. In this wide-ranging conversation with a16z Operating Partner Bob Swan—himself formerly CEO of Intel—Lisa lays out her vision for the evolution of compute within the AI ecosystem, touching not only on raw pow…
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