This podcast is hosted by biotech entrepreneur Sushant Kumar, Founder & CEO of Genefitletics. Through this exclusive health podcast, he addresses the information asymmetry in the preventive health space. He is currently building Genefitletics, which is a direct-to-customer Biotech company- that studies & analyses activities of single & multicellular microorganisms living on & inside human body to provide precision health interventions in order to eradicate epidemic of chronic diseases, cance ...
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The Opportunist is a podcast series by Story Cast that dives into successful careers of well known creatives, Brand Builders and Startup Founders from various corner of culture. We learn about the realities behind the dreams they've built with encouraging words of advice peppered along the way.
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We have spent decades avoiding one of the most essential & vital macromolecule-FATS to our own peril.You may hear these fitness folks propagating fats are bad & causing cardiovascular disease referring to an obsolete & obnoxious paper or theory of Ancel keys who claimed in 1958 that it is fat & cholesterol which causes heart disease.Obviously, thes…
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Discover your Biological Age Story- Health discourse with Sakshi & Sushant Ep 13
51:22
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51:22Aging is the future not because there is a wave of longevity companies measuring your biological age but assessment of biological age at system biology level gives a comprehensive picture of efficiency of your human & microbial cellular functions.Unfortunately, none of the longevity or so-called fitness companies have model & data in place to measu…
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Metabolic Therapy for Prevention & successful elimination of cancer- Ft. Dr Thomas N Seyfried
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59:16
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59:16In the year 2022, 1.46 million Indians developed cancer while over 9,00,000 lost their life.65% cancer mortality rate is the biggest cause of concern given that we have so many companies claiming to detect cancer early & number of therapies- radiation, chemo & immunotherapies to kill the tumours.Have you ever wondered why ?We have been stuck in the…
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Impact of Oxidative Stress on Longevity #biologicalage #aging #longevitysecrets #longevity
6:43
6:43
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6:43One of the important factors that directly impacts your longevity & biological age is oxidative stress.Oxidative stress is one of the culprits in the onset of various metabolic diseases & even cancer.What exactly is Oxidative Stress?It is a state of imbalance between pro-oxidant & antioxidant activities.Interaction between your biology with the foo…
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Prevent Cancer Ep.3 - How does #Cancer grows & spreads? #cancerawareness #cancercure #cancermedicine
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19:56
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19:5690% of cancer deaths are attributed to metastasis.What exactly is metastasis ?In simple words it is the spread of cancer cells from the primary tumour sides to different tissues & distant organs. The process involves local invasion, detach from primary site, enter( intravasate) into circulation/blood stream, evade immune attack, enter other tissues…
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Decoding difference between #cancercells & Normal Cells- #Cancer #Podcast Ep-2 #cancerawareness
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6:23
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6:23We all know cancer is nothing but uncontrolled cell growth & division. Mitochondria in every cell controls cell cycle. It is a kill switch. When there is mitochondria dysfunction, this kill switch is gone. The cells starts to proliferate & grow.The question arises what differentiates normal cells from cancer cells?It is how cells generate energy.No…
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Going beyond #somatic #mutation theory- Decoding cause of Cancer #cancerawareness #cancermanagement
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18:06Cancer has been regarded as a genetic disease caused by genetic mutations driven by somatic mutation theory. You would be have influx of number of DNA testing or early cancer detection companies claiming they could detect risk/early cancer onset looking at certain genetic mutations, circulating tumor cells or physical examinations These all are dri…
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Groundbreaking truth about Heart disease #worldheartday #hearthealth #cardiovasculardisease
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30:00On the eve of World Heart Day 2024, let us break all myths around onset & progression of cardiovascular disease.Cardiovascular disease is the number one killer globally with no preventative solutions as of now.Most of the #healthcare practitioners & #healthtech companies still blame cholesterol for development of cardiovascular disease while it is …
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Facts you should know about Microbiome Tests #microbiomehealth #microbiometest #guthealth
8:51
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8:51Over the last 4-5 years, we have seen a flurry of gut microbiome DNA testing companies, claiming they have an out of box solution to reverse most chronic diseases!I am afraid this is far away from reality!No doubt, Gut microbiome has a vital role to play in overall physiology but these companies have less than optimal approach on two fronts-These c…
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Cholesterol does not cause Heart Disease #cardiovasculardisease
14:05
14:05
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14:05Do you know which is the most complex machinery ever made on this planet earth? Yes , it's the human body! Our body is a sack of chemicals & biochemical reactions that need to work in synchrony to keep our body in homeostasis. It needs flow of electrons, voltage & current to keep all biological functions moving. Literally everything is connected- w…
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Can we detect early signs of chronic kidney disease?
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24:32Chronic Kidney Disease is a global health problem. The biggest issue lies in its late diagnosis during the progression of disease. The clinical manifestation & plasma level indications such as eGFR that can indicate kidney health are reduced only at advanced stages of disease development.However the fact is the changes in biology & chemistry at mol…
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Health Discourse with Sakshi & Sushant- Episode 12
25:52
25:52
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25:52It has been found that 33% of adult female population suffer from depression, while 1 in 5 men would have this growing mental health issue.Stress is rampant while millions of people deal with dementia & Parkinson's.While there are solution such as drugs & antidepressants to manage these growing mental health conditions, we have not seen any applica…
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Health Discourse with Sakshi & Sushant- Episode 11
34:14
34:14
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34:14We have become a protein obsessed nation! Have you ever wondered why?We are told we are deficient in protein! But does this apply to everyone? Is the entire adult population protein deficient? What is the basis of the claim ? How do we calculate deficiency?If you are recommended some X grams / kg of body weight to meet your protein requirement, you…
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Health Discourse with Sakshi & Sushant- Episode 10
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30:52
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30:52Metabolic disease is taking a giant leap forward with the number of people developing obesity, type 2 diabetes & more is increasing.Although we have all resources & tech in place, still we do not have any preventative solutions to stop these diseases from developing in the first place.There is need to understand-Food processing, farming practices &…
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Health Discourse with Sakshi & Sushant- Episode 9
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35:27
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35:27Digitise your body before you put a fork inside your mouth! If someone would have told you this 5 to 7 years ago, you would have told them you must be joking! Technology has taken leap & bounds over last few years still when it comes to nutrition as medicine, we get inclined towards that lucrative quick fix without understanding our unique biology …
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Health Discourse with Sakshi & Sushant- Episode 8
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39:45Last few years have seen advancement in technology which has opened up flood gates to revisit how we measure our health. This has transformed the methods of collecting healthcare delivery data & point of care diagnostics with usage of Wearables- Smart rings, smart watches & CGMHowever are the healthcare delivery data & plasma level indications real…
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Health Discourse with Sakshi & Sushant- Episode 7
30:29
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30:29Sexual health issues among male population, specifically, Erectile Dysfunction(ED), has become one of the major chronic health conditions with over 50% of male population in the age band of 40-70 years facing ED.Research has found that men having obesity or suffering from type 2 diabetes &/or high blood pressure are at high risk of Erectile dysfunc…
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Health Discourse with Sakshi & Sushant- Episode 6
30:08
30:08
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30:08Obesity is a global epidemic with more than a quarter of the population dealing with this metabolic syndromeWhile there are tens of thousands of solutions to suppress your weight/make you lose weight, 99% of them are band-aid solutions & do not focus on what makes you obese.Those companies &/or coaches, it is a financial model! You need to maintain…
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Health Discourse with Sakshi & Sushant- Episode 5
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17:50
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17:50Exercise has a vital role to play in fine tuning our physiology & overall health. A moderate exercise with 60-75 minutes per day , 3-5 days a week is important for various biological processes including regulating satiety level, cardiovascular disease, stress response & more. However, an important aspect is exercise performance. Right nutrition cho…
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Health Discourse with Sakshi & Sushant- Episode 4
24:35
24:35
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24:35Oral Illness continues to be a huge burden in India with more than 95% of Indians having dental caries & over 50% have periodontal diseases.Most of the current set of dental interventions are band aid solutions resorting to root canals, tooth fillings & more but misses out the most important aspect- the microbes living inside our mouth- ORAL MICROB…
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Health Discourse with Sakshi & Sushant- Episode 3
31:05
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31:05100 million people in India are dealing with type 2 diabetes & counting! India is called Diabetic capital of the world. We have all science & technology & even healthcare to address range of chronic diseases including type 2 diabetes but still the number of Diabetic population seem to increase with current healthcare industry having no clue how to …
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Health Discourse with Sakshi & Sushant- Episode 2
31:29
31:29
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31:29Solving & finding the underlying cause why people develop metabolic disease trilogy- Type 2 diabetes-Cardiovascular Diseases- Chronic Kidney Disease has been a nightmare.More so as our modern healthcare system, treat all three diseases separately & treat separate organs. What if all these three diseases are connected? Why are our healthcare profess…
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Health Discourse with Sushant & Sakshi- Episode 1
35:25
35:25
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35:25When it comes to chronic diseases, we are living in the dark. We do not know how it developed, why it developed & if someone develops a chronic disease say diabetes, cardiovascular disease, depression or more, he/she blames it on bad genes or bad luck. Well it's not bad genes or bad luck, it's some change in biology + chemistry going on before & du…
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Say YES to Nitric Oxide & NO to supplements | Myths behind supplements busted
28:46
28:46
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28:46Post COVID, people have become conscious of their health & are looking for solutions that can help them regulate their biology.However, this has been considered as an opportunity with a number of supplements & nutraceutical companies who have been offering standard OTC supplements- vitamin, mineral, prebiotics, probiotics, synbiotics & more for wor…
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Oral + Gut Microbiome & Colon Cancer- Interview with Dr Amine ZORGANI
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26:29Incidence of cancer is increasing & around 13% of the Indian population is at high risk of developing cancer with more representation from younger population.It is one of the most complex diseases & the current set of interventions are just on suppressing tumours through modern medicine methods- chemotherapy, immunotherapy, surgery & more with limi…
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We recently launched India's first oral microbiome genes expression solution which encompasses molecular insights into dental health, sexual health, reproductive health, metabolic health, brain & cognitive health, heart health & more.The microbes living in the mouth, the second largest colonised area for microbes after the gut, have been ignored fo…
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Molecular mechanism of inflammasome activation & onset & progression of type 2 diabetes
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25:42
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25:42Type 2 diabetes is a global epidemic with the number of people developing this disease is going to increase by 40% by the end of the year 2023. In India alone 100 million + people are dealing with this metabolic syndrome.We have seen a number of companies claiming they can reverse diabetes just by tracking blood sugar & Hba1c levels through CGM mac…
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Second episode of our ASKEDIOME is live now.Thanks Fatima for accepting our request being part of this exciting discussionThis episode unlocked mystery behind:1)Rheumatoid Arthritis: The role of gut microbiome2)Gut- heart connection3)All about chronic constipationThe question thread for our 3rd episode is now open. You may drop your questions here.…
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We are doing every bit to make interventions for your health as personalized & precise as possible!We make sure that response to your health queries & interventions have cutting scientific edgeFrom today, we are kick starting another initiative- ASKEDIOME- the weekly Q &A webcastEvery Tuesday, Genefitletics translational science team would stream Q…
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How Multi cellular Organisms Living on & inside our Body are programming our Biology for Health?
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30:15Our founder & CEO- Sushant Kumar in talks with Mr.Rupinder Singh, Founder- Biohouse Solutions &, serial entrepreneur & motivational speaker on how gut microbiome is shaping our biology for health. The discussion was focussed on -Why are we developing chronic diseases? - Why the healthcare system is not able to solve this epidemic. - DNA vs microbio…
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Over the last 5 decades, we have been grappling with chronic diseases! Chronic diseases have become an epidemic- disaster for mankind. Now it is time to separate functional medicine & preventive nutrition from modern medicine. Over the last few years, science is clear that underlying cause of every single chronic disease be it diabetes, obesity, ca…
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Should Your Body Stop Producing Cholesterol?
3:49
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3:49Let us talk about cholesterol today. Heart disease is one the most dreaded diseases globally & its impact is devastating for families. We are told to eat healthier & exercise daily to maintain a healthy heart. Cereal boxes & other so called healthy food boxes available in market are plastered with “ heart healthy” seals & claim to decrease your cho…
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Fireside Chat on How Gut Microbiome is the epicenter of our Health
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59:54
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59:54In Spite of such an advanced healthcare system, we are still grappling with chronic diseases be it Diabetes, Obesity, Cardiovascular diseases, Digestive issues or hormonal imbalances. Every year 41 million people die prematurely of these chronic diseases. The truth is these diseases are preventable. Our healthcare system as we see it today is best …
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Join us for Live Discussion on How Mirco-organisms in our gut influence our Health- Call for Participation
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1:49Hey folks, have you ever wondered why in spite of such an advanced healthcare system, 9% of the global adult population suffer from diabetes? Why does 10% of the female adult population suffer from PCOS? Why do heart diseases account for 1/3rd of deaths? Why 41 million die premature deaths every year due to chronic diseases? The fact of the matter …
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Be it weight loss, fat loss, obesity or muscle building, high protein consumption is considered to be the best strategy at play! Basic premise behind this is protein helps repair & growth of muscles, improve satiety level & keeps sugar level stable! This is the basic reason we are told to follow fat diets such as high protein, ketosis or other high…
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Расшифруй свое внутреннее здоровье - эпизод 7
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4:08Будь то потеря веса, потеря жира, ожирение или наращивание мышечной массы, высокое потребление белка считается лучшей стратегией! Основная предпосылка этого заключается в том, что белок помогает восстанавливать и наращивать мышцы, улучшать уровень сытости и поддерживать стабильный уровень сахара! Это основная причина, по которой нам советуют придер…
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Ya se trate de pérdida de peso, pérdida de grasa, obesidad o desarrollo muscular, el consumo elevado de proteínas se considera la mejor estrategia en juego. La premisa básica detrás de esto es que la proteína ayuda a reparar y desarrollar los músculos, mejora el nivel de saciedad y mantiene estable el nivel de azúcar. ¡Esta es la razón básica por l…
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سواء كان الأمر يتعلق بفقدان الوزن أو فقدان الدهون أو السمنة أو بناء العضلات ، فإن الاستهلاك العالي للبروتين يعتبر أفضل استراتيجية في اللعب! الفرضية الأساسية وراء هذا هو البروتين يساعد على إصلاح ونمو العضلات ، وتحسين مستوى الشبع والحفاظ على استقرار مستوى السكر! هذا هو السبب الأساسي الذي يُطلب منا اتباع أنظمة غذائية غنية بالبروتينات أو الكيتوزية أو غ…
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Have you ever faced a situation when a mild headache becomes a serious one & troubles you all day? You are not able to work, or do normal daytime activities! Doctors have determined a lot of reasons for the onset of such headache or migraine however the most prominent one which often goes unnoticed, until we are having a serious pain in our temple …
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هل سبق لك أن واجهت موقفًا يصبح فيه الصداع الخفيف مشكلة خطيرة وتزعجك طوال اليوم؟ أنت غير قادر على العمل أو القيام بأنشطة نهارية عادية! لقد حدد الأطباء الكثير من الأسباب لظهور مثل هذا الصداع أو الصداع النصفي ، لكن أهمها التي غالبًا ما تمر دون أن يلاحظها أحد ، حتى نشعر بألم خطير في معبدنا لعدة أيام ، هي خياراتنا الغذائية. نظرًا لضيق الوقت ، غالبًا ما …
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¿Alguna vez se ha enfrentado a una situación en la que un dolor de cabeza leve se convierte en uno grave y le preocupa todo el día? ¡No puede trabajar ni realizar actividades normales durante el día! Los médicos han determinado muchas razones para la aparición de tal dolor de cabeza o migraña, sin embargo, la más importante que a menudo pasa desape…
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Расшифруй свое внутреннее здоровье - эпизод 6
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4:42Вы когда-нибудь сталкивались с ситуацией, когда легкая головная боль становится серьезной и беспокоит вас весь день? Вы не можете работать или заниматься повседневными делами! Врачи определили множество причин возникновения такой головной боли или мигрени, однако наиболее заметной из них, которая часто остается незамеченной, пока мы не испытываем с…
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Is going on medication to manage your diabetes becoming a nightmare? A lot of folks suffering from type 2 diabetes end up having blood sugar levels of 200 plus early mornings even after having low carb &/or low GI food the previous night. Not to mention side effects of taking medication that can take a toll on overall metabolic health! An average i…
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Расшифруй свое внутреннее здоровье - эпизод 5
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6:39Становится ли кошмаром прием лекарств для лечения диабета? Многие люди, страдающие диабетом 2 типа, в конечном итоге имеют уровень сахара в крови 200 плюс рано утром даже после того, как накануне вечером съели пищу с низким содержанием углеводов и / или ГИ. Не говоря уже о побочных эффектах приема лекарств, которые могут сказаться на общем метаболи…
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¿Tomar medicamentos para controlar la diabetes se está convirtiendo en una pesadilla? Muchas personas que padecen diabetes tipo 2 terminan teniendo niveles de azúcar en sangre de 200 más temprano en la mañana incluso después de haber comido alimentos bajos en carbohidratos y / o con IG bajo la noche anterior. ¡Sin mencionar los efectos secundarios …
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هل أصبح تناول الأدوية للتحكم في مرض السكري كابوسًا؟ ينتهي الأمر بالكثير من الأشخاص الذين يعانون من مرض السكري من النوع 2 بمستويات سكر في الدم تصل إلى 200 بالإضافة إلى الصباح الباكر حتى بعد انخفاض الكربوهيدرات و / أو انخفاض نسبة السكر في الدم في الليلة السابقة. ناهيك عن الآثار الجانبية لتناول الأدوية التي يمكن أن تؤثر سلبًا على صحة التمثيل الغذائي ب…
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تُعزى وفاة واحدة من بين كل 4 حالات وفاة إلى أمراض القلب والأوعية الدموية في العالم. يموت أمريكي كل 37 ثانية بسبب أمراض القلب مع ما يقرب من 650 ألف حالة وفاة كل عام بسبب أمراض القلب والأوعية الدموية. هناك العديد من الطرق التي يمكن للناس من خلالها البدء في السيطرة على صحة قلبهم اليوم. قام علماء التغذية بإجراء تحسينات عميقة في أبحاث الأمراض ، مما يدل …
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One out of every 4 deaths is attributed to cardiovascular events in the world. Every 37 seconds, an American dies of heart disease with nearly 650,000 deaths every year due to cardiovascular disease. There are many ways people can begin to take control over their heart health today. Nutrition Scientists have been making profound improvements in dis…
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Расшифруй свое внутреннее здоровье - эпизод 4
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4:14Каждая четвертая смерть в мире связана с сердечно-сосудистыми заболеваниями. Каждые 37 секунд американец умирает от сердечного приступа, при этом ежегодно умирает почти 650 000 человек из-за сердечно-сосудистых заболеваний. Есть много способов, которыми люди могут начать контролировать свое здоровье сердца уже сегодня. Ученые-диетологи добились зна…
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Una de cada 4 muertes se atribuye a eventos cardiovasculares en el mundo. Cada 37 segundos, un estadounidense muere de una enfermedad cardíaca con casi 650,000 muertes cada año debido a una enfermedad cardiovascular. Hay muchas formas en que las personas pueden comenzar a tomar el control de la salud de su corazón hoy. Los científicos de nutrición …
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