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Christine Grella, Senior Research Scientist with The Lighthouse Institute, joined us to discuss her decades of research on substance use disorders, with a focus on the particular challenges facing women.
Key Highlights:

  • Chris’s early work at UCLA that focused on incarcerated men, after which most of her work focused on substance use among women.
  • Longitudinal insights: 30-year study revealed diverse recovery pathways beyond simple success/failure outcomes.
  • Gender disparities: Women face more severe health consequences and historically greater stigma, while changing gender roles have reduced protective factors for girls. For Amy Winehouse fans (which includes Chris and her interlocutor), we also discussed how her tragic demise, which, like many women with substance use issues, was largely driven by her toxic romantic relationship.
  • Opioid crisis shift: Crisis evolved from isolated heroin use to widespread prescription opioids and fentanyl affecting younger, broader demographics.
  • Treatment integration: Moved from stigmatized, isolated clinics to mainstream primary healthcare settings.
  • Policy evolution: Federal approach shifted from incarceration-focused to more balanced treatment and prevention strategies.
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43 episodes