Lionel fields calls from a variety of listeners, discussing traditional holiday topics such as the history of the meal and the massive Macy's Thanksgiving Day Parade balloons. The wide-ranging discussion quickly moves from lighthearted caller anecdotes, including a recurring gag about a caller who fell asleep on hold, to more substantial topics of current events and philosophy. Lionel introduces recent studies detailing the negative cognitive impact of excessive smartphone use and a proposed quantum physics theory suggesting that consciousness exists as a fundamental field of the universe. Extended conversations also focus on the unique experience of those who work overnight, particularly a long-haul truck driver who discusses the potential threat of autonomous vehicles and the community he finds on the road.

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