Is berberine really 'nature's Ozempic' as social media claims? With 127 million TikTok views, this trending supplement promises dramatic weight loss—but the scientific reality is shockingly different. Diving deep into the research, we expose how a small 2008 pilot study has been wildly misrepresented by supplement marketers. While berberine shows modest glucose control benefits, its weight loss effects are minimal: just 2-4 kilograms compared to Ozempic's 15-16 kilogram average. This episode reveals the dangerous gap between viral health claims and actual medical evidence, showing how preliminary research gets weaponized into misleading marketing that could delay people from seeking proven treatments. A quick note—the opinions and analysis shared on Truth Seekers are our own interpretations of published research and should not be used as medical, financial, or professional advice. Always consult qualified professionals for decisions affecting your health or wellbeing.