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Transformation in Trials

Sam Parnell & Ivanna Rosendal

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A podcast about the transformations in clinical trial. As life science companies are pressured to deliver novel drugs faster, data, processes, applications, roles and change itself is changing. We speak to people in the industry that experience these transformations up close and make sense of how the pressure can become a catalyst for transformation.
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Send us a text Dr. Shervin Molayem shares his journey of innovation in dentistry, starting with his discovery of a connection between periodontal disease and COVID-19 severity that became the world's most-read dental article of 2020. He discusses groundbreaking technologies including AI-powered diagnostic tools and a revolutionary non-surgical trea…
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In this episode, Khepri interviews Sneaky Snake about how to be successful with Military Orders! Sneaky has been absolutely killing it with Military Orders, playing it intensely and even coming in 13th out of more than 170 contenders in the IGL 2025 Satellite. His schedule was insanely stacked, take a look at his matchups, he got no easy breaks! We…
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Send us a text Chris Wood discusses how early diagnostics of lung cancer through artificial intelligence and medical imaging can lead to better survival rates through early intervention. • Lung cancer takes more lives than breast, prostate and colon cancer combined, with approximately 70% of cases caught at late stages • The National Lung Screening…
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Send us a text Building high-performing teams in life sciences requires understanding how neurodiversity can be an advantage and designing work systems that enable different brain types to collaborate effectively. • A high-performing team continues to function when everything around it has fallen apart • Star players can become crutches that mask u…
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Send us a text Sebastian Andruszczak, Chief Growth Officer at Holisticon (part of the Nexer Group), brings fresh perspective to the conversation around generative AI adoption in pharmaceutical companies. Drawing from his unique background in sales, marketing, and technology, Sebastian cuts through the hype to address fundamental challenges that pre…
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Ray and a Pro Goblin tackle JSA, who is now a full fledged Faction! Lists: Standard Shikami-Hatamoto-ShizokuhE0DanNhASCBLAIBAQAJAIMFAQIAAIceAQIAAICnAQIAAIPkAQEAAIchAQIAAIccAQMAAIcjAQIAAIckAQIAAICQAQsAAgEABgCHHwEGAACD5wEHAACAngECAACAogEBAACHKQEBAAAyAQEA "Well rounded" list that I talked about. My version in Adepticon cut the Shizoku and made upgrade…
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🔍 In this TL;DR episode, Anna and Nate unpack why calling AI outputs “hallucinations” misses the mark—and introduce “AI Mirage” as a sharper, more accurate metaphor. From scoring alternative terms to sparking social media debates, they show how language shapes our assumptions, trust, and agency in the age of generative AI. The takeaway: choosing th…
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Send us a text Why do we wait until we're severely unwell before seeking help? In this thought-provoking episode, I'm joined by Eva Papadopoulou, a mental health professional and expert in digital and AI-enabled healthcare solutions, to explore the transformative potential of preventative mental healthcare. Eva reveals the stark reality of our curr…
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It still starts with seeing groups of needs, and offers in your community. However, the "Potluck" method of neighbourhood timebanks isn't always the best way to get started. Mike takes us through his journey & show how to manage all these different things at once! To chat with him, use this Calendly link: https://calendly.com/openmike And check out…
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🔍 In this TL;DR episode, Emmie Hine (Yale Digital Ethics Center) makes the case for Europe’s leadership in open-source AI—thanks to strong infrastructure, multilingual data, and regulatory clarity. With six key policy recommendations, the message is clear: trust and transparency can make EU models globally competitive. 📌 TL;DR Highlights ⏲️[00:00] …
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In this episode, Khepri inteviews Brooke on his recent victory in the IGL 2025 Satellite tournament! This is one of the most fiercely competitive Infinity events on the planet, with a massive turnout. Join as a we discuss the lists he made, the plans he made and the games he played. Brooke doesn't play a cookie cutter build, and there is plently of…
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Send us a text Rob Freistat, President of Uncommon Cures, discusses how clinical trials are transforming to accelerate drug development and ensure patients receive treatments faster, particularly in the rare disease space. • Current market uncertainty and investment challenges in biotech, especially for rare disease research • Approximately two-thi…
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🔍 In this TL;DR episode, Milton Mueller (the Georgia Institute of Technology School of Public Policy) argues that what we call “AI” is really just part of a broader digital ecosystem. Instead of vague, top-down AI regulation, he calls for context-specific rules that address actual uses—like facial recognition or medical diagnostics—rather than the …
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Vincent Ouellette-Destroismasions introduces us to Quebec's community currency platform, and the growing presence of alternative currencies in Canada. Vincent's program has successfully included many local businesses as well as individuals, and the strategy we share with you for finding funds to run your program makes this an episode you won't want…
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Send us a text Jonathan Hill takes us on a fascinating journey through the cutting-edge world of DNA sequencing and its revolutionary potential for early disease detection. As both an academic professor at Brigham Young University and co-founder of Wasatch BioLabs, Hill shares how third-generation sequencing technologies are transforming our abilit…
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🔍 In this TL;DR episode, Kevin Frazier (University of Texas at Austin school of Law) outlines a proposal to realign U.S. copyright law with its original goal of spreading knowledge. The discussion introduces three key reforms—an AI training presumption, research safe harbors, and data commons—to help innovators access data more easily. By reducing …
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In this episode, Khepri interviews ITS Season 15 winner, Axel! We go over his favorite White Banner profiles, how he uses them, why his lists are almost always controversial, and how he approaches the game. List 1: gM0Md2hpdGUtYmFubmVyC0NhcmFqaWxsby0xgSwCAQEACQCAlgELAACF2QEEAACG2AEHAACG3AEBAACF3AEBAACAiAECAACAiAECAACHMQEEAACHMQEEAAIBAAcAhd4BAwAAgIY…
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Send us a text Vectors are the unsung heroes of cell and gene therapy—molecular couriers that transport therapeutic genes into human cells to treat disease. But as Alan Griffith, Head of Global Operations at Vector Builder reveals, creating these sophisticated delivery vehicles is far more complex than most realize. Drawing from over a decade of ex…
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🔍 In this TL;DR episode, Paul Keller (The Open Future Foundation) outlines a proposal for a common opt-out vocabulary to improve how EU copyright rules apply to AI training. The discussion introduces three clear use cases—TDM, AI training, and generative AI training—to help rights holders express their preferences more precisely. By standardizing t…
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In this episode, Khepri inteviews OrderMonkey on how he plays Operations Subsection of the SSS. OrderMonkey just won the Furor Teutonicus 2025 with his unconventional style of OSS, so it's time for a deep dive into how he plays the faction! This is the second time we've interviewed OrderMonkey on the show, if you want to hear the previous episode, …
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Send us a text The untapped potential of electronic health records has long been recognized in clinical research, but extracting meaningful insights from this treasure trove of data has remained an elusive challenge—until now. Vish Srivastava, founder of Century Health, reveals how artificial intelligence is revolutionizing real-world evidence by u…
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In this episode, Khepri inteviews Lokie, AKA Daboarder on how he plays the brand new Kestrel Colonial Force. Daboarder is a great strategist and has been playing, thinking and writing about PanO for three editions now. He also has a scientists obsession with experimenting with different units and combinations, so be prepared, as we're not covering …
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🔍 In this TL;DR episode, João Quintais (Institute for Information Law) explains the interaction between the AI Act and EU copyright law, focusing on text and data mining (TDM). He unpacks key issues like lawful access, opt-out mechanisms, and transparency obligations for AI developers. João explores challenges such as extraterritoriality and trade …
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Send us a text Join us for a conversation with guest Shelli Pavone, co-founder of Inlightened, to uncover the untapped potential of diversity in clinical trials. Discover how historical mistrust, structural barriers, and exclusion criteria continue to hinder diverse patient recruitment. Shelli sheds light on the transformative impact inclusive tria…
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In this Episode, Raymon goes over his Top 23 ranking of the current missions in ITS 16. Here the list of custom tweaks too try out: Acquisition - Alternative Scoring: At the end of the round activate more Antennas (1 objective point per round) At the end of the round control more Antennas (1 objective point per round) At the end of the round contro…
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Send us a text In this episode we dive into Brain-Computer Interface (BCI) technology, where the brain's faint signals are harnessed to create life-changing applications. Andreas Forsland and Greg Johns emphasize the importance of community-driven innovation, guided by the Brainiac Council—a unique assembly of patients, caregivers, and experts. Thi…
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🔍 In this TL;DR episode, Anna Tumadóttir (Creative Commons) discusses how the evolution of creator consent and AI has reshaped perspectives on openness, highlighting the challenges of balancing creator choice with the risks of misuse. Examines the limitations of blunt opt-out mechanisms like those in the EU AI Act, the implications for marginalized…
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In this episode, Khepri interviews Steve AKA KingButt on how he plays Va(runa)nilla PanO in N5. KingButt had a smashing ITS15 with Varuna, and has pivoted to Vanilla PanO in N5 with great success. Join us as he shares his thoughts on the faction, the units and why the best strategy for PanO is to shoot everything and wait for the dust to clear to p…
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🔍 In this TL;DR episode, Carys J Craig (Osgoode Professional Development) explains the "copyright trap" in AI regulation, where relying on copyright favors corporate interests over creativity. She challenges misconceptions about copying and property rights, showing how this approach harms innovation and access. Carys offers alternative ways to prot…
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Send us a text This episode reveals alarming statistics about patient access to clinical trials, highlighting that only 3% of patients currently have access to participate. Our guest, Jill Pellegrino, CEO of Auto Recruitment, shares innovative strategies to engage the other 90% of the patient population and discusses the importance of digital adver…
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Did you know that timebanking is just 1 of many types of community currency? Sierra Love introduces us to the Calgary Dollar; its history, its impact, and a little bit of its future. Sierra also presents how they were able to champion the use of their community currency for rent and groceries in their city; a must have for any CC or timebank!…
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In this episode, Khepri interviews Jordan from the Loss of Lieutenant podcast about Vanilla Combined Army in N5! Jordan had a great run with vCA in N4, with excellent showings in the big Australian 2 day events, and he shares his vision for the faction and how to list build for it. We cover what units got better, which got worse, how he's building …
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🔍 In this TL;DR episode, Ariadna Matas (Europeana Foundation) discusses how the 2019 Copyright Directive has influenced text and data mining practices in cultural heritage institutions, highlighting the tension between public interest missions and restrictive approaches, and explores the broader implications of opt-outs on access, research, and the…
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🔍 In this TL;DR episode, Martin Senftleben (Institute for Information Law (IViR) & University of Amsterdam) discusses how EU regulations, including the AI Act and copyright frameworks, impose heavy burdens on AI training and development. The discussion highlights concerns about bias, quality, and fairness due to opt-outs and complex rights manageme…
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🔍 In this TL;DR episode, Mark Lemley (Stanford Law School) discusses how generative AI challenges traditional copyright doctrines, such as the idea-expression dichotomy and substantial similarity test, and explores the evolving role of human creativity in the age of AI. 📌 TL;DR Highlights ⏲️[00:00] Intro ⏲️[00:54] Q1-How does genAI challenge tradit…
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Send us a text Why has SAS been the cornerstone of clinical trials for decades, and what is causing the shift to R now? Join us on "Transformation in Trials" as we explore this pivotal transition with Sunil Gupta, a seasoned programmer who has navigated both worlds. Sunil elaborates on SAS's long-standing dominance due to its robust programming cap…
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Send us a text Prepare to transform your understanding of vendor oversight in clinical trials as we welcome Jessica Cordes, a senior consultant and trainer at the Clinical Excellence Consultancy. Jessica brings her wealth of experience to highlight the intricate responsibilities that sponsors must navigate when outsourcing tasks. Our conversation p…
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Part 2 without glitches! but first, an Oby shout out: It's that time of year again, time for me to do my 24/36hr stream in support of SickKids. I will be attempting a 24 hour stream from Saturday, November 16th at 9:00 am - Sunday, November 17th at 9:00 am. If I raise $750 before the 24hrs is up the stream will be extended to 36hrs (ending at Novem…
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With N5 on the Horizon, Raymon and Logan take one good look back at Ariadna and how they enjoyed it in N4. They go over the evolution of Ariadna from N3 too N4, how Ariadna is holding up currently, and their favorite profiles from the sectorials. They poor one out for the Sectorials that are leaving, and hopefully will make a valliant return in the…
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🔍 In this TL;DR episode, Jacob Mchangama (The Future of Free Speech & Vanderbilt University) discusses the high rate of AI chatbot refusals to generate content for controversial prompts, examining how this may conflict with the principles of free speech and access to diverse information. 📌 TL;DR Highlights ⏲️[00:00] Intro ⏲️[00:51] Q1-How does the …
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🔍 In this TL;DR episode, Jurgen Gravestein (Conversation Design Institute) discusses his Substack blog post delving into the ‘Intelligence Paradox’ with the AI lab 📌 TL;DR Highlights ⏲️[00:00] Intro ⏲️[01:08] Q1-The ‘Intelligence Paradox’: How does the language used to describe AI lead to misconceptions and the so-called ‘Intelligence Paradox’? ⏲️[…
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