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Bloody Minded

Bloody Minded Crew

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Baffled by blood? Confused by coags? Traumatised by TTP? Planning on quitting medical school because you've just finished haem block? Join the registrars of the Bloody Minded Crew as they tour the world of haematology one topic at at a time while procrastinating from their day jobs. Your time is precious, so to maximise your return we look at each topic at a variety of levels so you can tailor your learning. Check out more at www.bloodyminded.com.au
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Ask The Expert from BloodStream Media is a podcast series features hematologists and other healthcare experts answering listener-submitted questions about hemophilia, von willebrand disease, and other inherited bleeding disorders. Learn more at BloodStreamMedia.com. The content contained within Ask The Expert is for informational purposes only. Please consult your health care provider before making any decisions about treatment.
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The Opinionated Bruhtha’s

Epic Echo Productions

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Welcome to The Opinionated Bruhtha’s! Buckle up for a rollercoaster of unfiltered opinions where entertainment news meets the world of politics. Join the unapologetic Bruhthas as they dissect the latest in showbiz and politics with no holds barred. From celebrity scandals to government shenanigans, nothing is off-limits. Get ready for passionate rants, candid debates, and guests who aren't afraid to speak their minds. If you're seeking unfiltered takes on the juiciest stories from Hollywood ...
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Support the show and shop at the Nitty Gritty Nursing esty shop! https://nittygrittynursing.etsy.com Are you a nursing student who struggles to understand nursing concepts your professor is teaching you? Do you wish there was a simple bite sized podcast to help further your knowledge base? Then you've found the right podcast. Nitty Gritty Nursing is a podcast designed for nursing students trying to understand how to care for different types of patients you might encounter with an acute care ...
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Sometimes something comes along that puts a chill down the spine of every doctor. Any conversation that starts with "Oh hey do you remember that patient you saw...?". Mystery meat day in the cafeteria. Dealing with hospital executives. For these times in life you need a guide. Today we'll be covering one of those spine-chilling clinical scenarios w…
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Come one come all to see the thinnest extended reference in the universe. Draped over not one but TWO episodes, the Bloody Minded Crew continue to make vaguely topical references to popular recent films. Look - we go outside and experience the full gamut of popular culture. Oh and we finish up our discussion of thrombophilia testing in the lab - lo…
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Lions and tigers and… thrombosis? Oh my! Join the Bloody Minded Crew on the yellow brick road to visit the emerald laboratory and see the wonderful wizard of clots - your friendly laboratory coagulation scientist! Put on your blood red ruby slippers and join us for this bumper lab episode as we learn about how exactly we test for Protein C, S and a…
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In this episode of Ask the Expert, Amy B. dives into the future flow of hemostasis research, exploring the cutting-edge therapies shaping bleeding disorder care. Join Drs. Patrick Ellsworth, Janice Staber, and Ben Samelson-Jones as they break down rebalancing agents, RNA therapies, and patient-driven discoveries that are guiding smarter, more preci…
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“HATE. LET ME TELL YOU HOW MUCH I'VE COME TO HATE YOU SINCE I BEGAN AS A HAEM REG. IF THE WORD HATE WAS ENGRAVED ON EACH NANO-ANGSTROM OF THE HUNDREDS OF MILLIONS OF CONSULT NOTES I HAVE WRITTEN IT WOULD NOT EQUAL ONE BILLIONTH OF THE HATE I FEEL FOR YOU ORDERING THROMBOPHILIA TESTING INAPPROPRIATELY.” Woah - Let’s calm down, that's a bit much. Cal…
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We're nearly out of pipes to clean - Join us for the world's worst roadtrip we venture into the lesser known parts of human plumbing and tackle unusual site thromboembolism. From splanchnic clots, uterine and testicular thrombi it's clots as far as the eye can see (and those it can't like CRVO!) Timestamps: 0:58 - ROADTRIP 4:07 - CVST 11:07 - CVST …
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It's said that beauty is skin deep but you know what else lurks just under your epithelium - CLOTS! Nick, Cale and Bashar head very slightly under our outer layer to the peripheral vasculature in this increasing tortured metaphor as we learn on our shortest episode to date about what to do when those not so deep vessels fill with thrombus. Timestam…
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D-ismayed by D-readful D-ressing D-owns by your D-emonstrably D-eplorable registrar? . Join de Bloody Minded Crew for a Tour D-Force of D-Dimer D-rama as we D-issect and D-iscuss this most D-ifficult of D-iagnostic tests! Timestamps 2:14 - What is a D-Dimer and where does it come from? 6:57 - FXIII and D-Dimer 7:49 - Fibrinolysis and other degradat…
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Join host Amy Board as we continue to dive into the evolving world of bleeding disorder treatments. This episode of Ask the Expert explores how emerging therapies—like rebalancing and non-factor agents—are tested, monitored, and kept safe. With insights from Drs. Mark Redding, Janice Stabler, and Tammy Singleton, we break down the complexities of d…
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“Give me a 2cc bolus of clot stat Emma. No wait - not there!” But it was too late, and Em-Bolused the 2cc of clot straight to the lungs”. Join the Bloody Minded Crew as they get to the heart… no get to the lungs of the topic of Pulmonary Embolism. VanQuish the V/Q and CriTically aPprAise the CTPA with these acronyms that are just as bad as a cardio…
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Calves, thighs, arms and more, Clots can form inside them all! Join your hosts Cale, Bashar and Nick as they take a deep (hah) dive into the nitty-gritty things you should know about managing DVTs of the extremities TIMESTAMPS 0:54 - Intro to Extremity Clots 3:49 - Veins of the Lower Limb 5:54 - History & Exam Lower Limb 10:54 - Phlegmasias 15:52 -…
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Philip K. Dick once wrote, “Perhaps if you know you are insane then you are not insane. Or you are becoming sane, finally. Waking up.” Waking up, that is, not to the alternative history universe where the Axis won WWII but rather, to a new bonus episode on Castleman disease! Join Cale, Bashar and Nick as we explore one of Haem’s most zebra diagnose…
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In this episode of Ask the Expert, we focus on women with bleeding disorders — a group that has historically been overlooked in research and clinical care. Heavy menstrual bleeding, mild and moderate hemophilia, and von Willebrand disease have often gone underdiagnosed or mischaracterized, leaving many women without the care they need. Amy Board si…
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Have you stumbled onto the haematology ward only to discover patients on bizarrely named BiTE & CART therapy? Why are we giving patients CARTs? Do they come with a horse? Why does everyone freak out when these patients are febrile? Why is everyone so hung up about handwriting? What are these weird drugs? It's OK – we are here once more to demystify…
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Bamboozled by basophils bountiful booty of granules? Let’s begin brilliantly with a basophil based bonanza. Buckets and buckets of brazenly basophil related bonus banter. You beauty! But, beware the bawdy, boisterous boys babbling brobdignagian-ly about BASOPHILS. It sounds better if you read it in Hugo Weaving’s voice and it’s the 5th of November …
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The mighty eosinophil had triumphed. The last parasitic worm lay vanquished beneath his granule-studded pseudopodia. For years, he’d battled helminthic scourge, a hero in mucus armor. But now, with no foes left to smite, he grew restless. He turned his sharp gaze to pollen, peanuts, and pet dander. "Troublemakers," he muttered, unsheathing his cyto…
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This week on Ask The Expert, the script is being flipped for patients with inhibitors and rare factor deficiencies! For years, treatment options were scarce—or even nonexistent. Now, rebalancing agents are changing the game, restoring clotting balance without relying on replacement factors. Amy is joined by Dr. Ben Samuelson Jones, Dr. Tammy Single…
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Put on your monocles and kimonos and hop on the monorail to our episode composed of monotonous monologues, monogamously dedicated to that most monolithic and sometimes monoclonal of mononucleated cells. We are monobviously talking about the monocyte. TIMESTAMPS 0:57 - Mono-Cyte! 2:50 - What is a monocyte? 4:20 - Monocyte subclasses 6:00 - Role of m…
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Behold the field in which I grow my cells and see that it is barren. It’s out of the frying pan and into the aplastic fire with not a cell in sight. Join Nick, Cale and Bashar without two neutrophils to rub together as we talk about an approach to that most concerning of FBC features - pancytopenia. TIMESTAMPS 2:22 - Definition of pancytopenia 4:23…
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Once again the Bloody Minded Crew have ventured out of the lab to find and trap another haematology registrar from the wards and convince them to come back to the show and talk about cells. Join haematology registrar Dr Lise Kempler as she teaches the team about what to do when that lymphocyte number just creeps up and up and up. TIMESTAMPS 2:34 - …
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Whilst most of haematology is spent looking forlornly into the empty neutrophil cupboard like old Mother Hubbard post chemotherapy, the pendulum can also swing to the other extreme. Join us as we unpack the reactive and not-so-reactive causes of a neutrophilia so you don’t get too left-shifted on the wards. TIMESTAMPS 2:18 - Apologies to the Welsh …
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Rev your engines and put the pedal to the metal on a wild ride through the clotting cascade! Amy Board and a pit crew of medical experts take you on an uproarious recap journey through the first six episodes, using engines, dominoes, and treasure maps to drive their points home. But hold onto your helmets—there's fresh and exciting science just aro…
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A lone neutrophil stands alone against a horde of gram negative bacteria. He is the last of his kind, the single granulocyte rising from the ashes of a marrow once verdant with haematopoiesis, now overrun with blasts. As the endotoxin rushes towards him, he smiles, for on the horizon he can see the glimmer of tazocin rushing through the blood vesse…
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There’s a problem with billionaires at the moment. Every day, you make a hundred billion platelets. For some in our society, even that colossal quantity isn’t nearly enough. They strive ever onward for even more. Unfettered platelet production all the time forever - after all the number can only go up. But mo’ platelets leads to mo’ problems. Go on…
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Are you a platelet that has been conjugated to an antibody? Sequestered in a spleen? Diluted out by too much saline? Had your precious gold stolen from you? Then you might be entitled to thrombensation! Listen to this episode to learn how we can help YOU approach thrombocytopenia. TIMESTAMPS 2:23 - Striking gold where you least expect it 4:40 - Def…
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Our half empty cup from last week has now runneth over! If having low red cells is a bad thing, then having an extremely high amount must be a good thing, right? WRONG! Join the Bloody Minded Crew as we explore what happens when we’re on the other side of that Goldilocks zone of red cells. Remember that episode of the Simpsons where they try and fo…
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In this episode of Ask the Experts, host Amy Board breaks down one of the most exciting developments in bleeding disorders treatment — rebalancing agents. Think of your body's clotting system like a seesaw: when everything's working right, it's balanced. But in bleeding disorders, the scale tips. Instead of adding what's missing (like clotting fact…
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All that blood study making you faint, fatigued and short of breath? Well, you might be anaemic but how can we tell why? Join us on our first expedition of this season of highs and lows as we take apart the full blood count one episode at a time. Let’s start with an approach to a cup half-empty of blood - anaemia! TIMESTAMPS 2:10 - The Motto of Hae…
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Send us a text In this episode I breakdown the pathophysiology of the terrible disease process known as Huntingtons and talk about how patient's who develop this present, what interventions to consider, and how to evaluate and educate patients and their families. Disclaimer: The mention of mental health screening, which include screening for suicid…
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Learning to count is hard. Learning to count cells is harder. Luckily we've got an expert with us today to show us the basics. Welcome back to a new batch of episodes where we unpack the highs and lows of haematology and teach you what to do with those pesky out of range blood counts. But to do that we need to know where the numbers come from. We d…
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Have you been asked to call for a Haematology consult and are now considering hiding in a toilet? Never fear! You can listen to this podcast from the hospital bathroom AND learn some fantastic tips and tricks to help us help you! Dr Alison Chandler is back in the studio and we're aiming for future consults with at least 50% less crying – and that’s…
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Send us a text In this episode I talk about that pathophysiology baseline knowledge you need to understand to put the pieces of autonomic dysreflexia together. I then break down how patients who may experience this present, what interventions you'd want to consider from the nursing perspective and the evaluation and education considerations you bri…
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Bashar was tasked with finding an expert to talk to about blood banking. He decided to cold-email the best transfusion-educator in the world who is probably responsible for hundreds if not thousands of haematology trainees understanding blood banking. Turns out he's an absolutely lovely guy who decided to spend an hour of his Monday morning chattin…
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In this episode, Amy trades medical jargon for construction metaphors as she takes us on a journey through hemostasis, the body's natural way of stopping a bleed. But what happens when the repair crew is understaffed—or missing entirely? That's where factor replacement therapy comes in. Amy and our experts explain how it works, why timing matters, …
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Red cells. White cells. Platelets. Plasma. Proteins. By your powers combined I am Captain… Whole Blood? Wouldn’t it be so much easier if we could work with each of these blood components individually. After all, we have to get them in a bag to donate to people. Before we swear off transfusion for the time being, join the Bloody Minded Crew as we le…
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Join our visiting expert Dr Eoghan Molloy - Multitalented transfusion medicine specialist and consultant haematologist at Cork University Hospital to teach us how to cross the ABO Rubicon and provide transfusion support in ABO mismatched transplantation. Visit the lab and see what happens to the forward and reverse group when you're in the middle o…
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FOUR Antibodies. THREE Animals. TWO Crying Haem Registrars. ONE TEST - The MAIPA. Actually maybe more than two crying haem registrars. How many antibodies are too many antibodies to have inside a lab test? One? That’s just a DAT. Two? A mere sandwich ELISA. But the Monoclonal Antibody Immobilisation of Platelet Antigens (MAIPA) - that’s not just th…
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On this exciting episode of Ask the Expert, join Amy as we delve into the fascinating world of blood clotting and anticoagulant therapy. We'll explore the clotting process with fun and relatable party analogies, featuring expert insights from Dr. Ben and Dr. Patrick. Discover how vital components like Protein C, Protein S, antithrombin, and TFPI wo…
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Have you ever looked at your wallet after a big night out and seen that all your dollars have been conjugated to alloantibodies and phagocytosed by macrophages? Then you know what it’s like to transfuse a platelet refractory patient! Join us as we take a tour of platelet refractoriness and do our best to find some HLA-matched dollars for rent this …
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Has this season been too simple? Want to up the difficulty? First of all you have issues, but second of all, welcome! It’s time to talk about all the things we don’t tell people about in the wider hospital - rare blood groups, subgroups, laboratory tips, tricks and more on this bumper In The Lab episode. Timestamps: 0:52 - How to get rich quick 3:5…
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What’s scarier than picking blood for one patient? Picking blood for TWO patients where one of them is inside the other (or only very recently outside). Obstetrics isn’t immune to the acronym train so join Nick, Cale and Bashar as we talk about HDFN, RhD prophylaxis and that OMG sensation that comes when looking after some of our smallest patients.…
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Dive into the crucial roles of Factor VIII, Factor IX, and thrombin in the blood clotting process. Hosts Amy and Patrick introduce expert Dr. Benjamin J. Samelson-Jones to discuss the interplay between these factors, including how they activate each other and form clots. Featuring insights from Dr. Mark Reding on the myriad functions of thrombin, t…
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This episode of "Ask the Expert" titled "Striking the Right Balance – Why Does it Matter in Hemophilia Treatment?" delves into the concept of rebalancing in hemophilia treatment. Hosted by Amy Bord, the episode features expert insights from Dr. Ben Samuelson Jones, Dr. Patrick Ellsworth, and Dr. Mark Redding. They explain how hemophilia treatments …
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IVIG & Rituximab – both involve Antibodies – and both can lead to infusion reactions that you may be called to as a junior doctor. But where do these antibodies even come from? Why are we even giving these treatments? What are you meant to do when called to review the patient? Head back to the wards, get your cheese ready and welcome back consultan…
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In this episode of 'Ask the Expert,' host Amy Board dives into the clotting cascade and explains how our blood clots. Alongside experts Dr. Ben Samuelson Jones, Dr. Amy Dunn, Dr. Mark Redding, and Dr. Patrick Ellsworth, Amy unpacks the complexity of the hemostatic system, discusses new treatments for hemophilia, and explores both the clotting and r…
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Ask the Expert is back with a twelve-episode deep dive into the evolving landscape of a groundbreaking new class of therapies in hemophilia treatment—rebalancing agents. Through expert insights and discussions, our new season, Hemophilia: On Balance, unpacks complex science to make it accessible and relevant to the hemophilia community. Episodes wi…
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Keen to augment your blood transfusion game but confused as to when, where and why? Join the Bloody Minded boffins as we cover all the major modifications to blood products you can order. More importantly, why you should and sometimes shouldn't bother ordering them. Have a sensible conversation with your blood bank after you listen to this episode.…
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Perfectly balanced, as all things should be. All that blood doesn’t just arrive when you snap your fingers together. The REALITY is you need the TIME and SPACE to thaw that frozen plasma and the strength of MIND to keep all the components in the right ratios. Only the chosen few with the POWER of transfusion medicine and the SOUL of the laboratory …
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