Technology's daily show (formerly the Technology Brothers Podcast). Streaming live on X and YouTube from 12 - 3 PM PST Monday - Friday. Available on X, Apple, Spotify, and YouTube.
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Exploring all things genetics. Dr Patrick Short, University of Cambridge alumnus and CEO of Sano Genetics, analyses the science, interviews the experts, and discusses the latest findings and breakthroughs in genetic research. To find out more about Sano Genetics and its mission to accelerate the future of precision medicine visit: www.sanogenetics.com
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LIVE FROM CONFIG: Jeremy Hindle, Nairi Tashjian Hourdajian, Andrew Reed, Elliot Jay Stocks, John LePore, Marty Ringlein
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OpenAI Launches Codex, Meta Delays Llama 4 Behemoth | Matt Grimm, Kevin Weil, Blake Scholl, Tim Fist, Chris Best, Sean Henry
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Airbnb 2.0, Warren Buffett Exclusive in WSJ, Apple to Support Brain-Implant Control | Alex Blania, Eugenia Kuyda, Josh Wolfe, Jason Fried, Delian Asparouhov
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EP 187: Rethinking germline gene editing and revolutionizing women’s fertility with Helen O’Neill
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38:38Summary: This week on The Genetics Podcast, Patrick is joined by Helen O’Neill, molecular geneticist, founder of Hertility Health, and associate professor at University College London (UCL). They discuss how Helen’s experience as an identical twin sparked her interest in genetics, her firsthand account of the CRISPR baby controversy, and why stubbo…
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Open-Source AI, a16z's Playbook | Marc Andreessen & The a16z Partnership, Bryan Johnson, Chris Pedregal, Joshua Browder
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Tesla Robotaxis, Saudi Arabia, AI in Big Tech, Art Market Update + Guests
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Crémieux, Tess Cameron, Eoghan McCabe, Pippa Lamb, Jack Dreifuss, David Tisch, TJ Parker, Surprise U.S.-China Trade Deal, Trump EO on Drug Prices, New Air Force One in 2025?, Perplexity Valuation Surge ...
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Mother's Day Gift Guide, Rorra in WSJ, Morgan Housel, Mehul Nariyawala, Sonya Huang, Stanford Review, Will Quist, Aidan Dewar, George Maloney
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Daniel P. Driscoll, General Randy A. George, Gary Vaynerchuk, Harley Finkelstein, Delian Asparouhov, Will Ahmed, Adam Porter-Price, Jack Altman, David Haber, Alex at Hallow
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EP 186: Unpacking the science and myths around obesity and health with geneticist and author Giles Yeo
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50:15This week on The Genetics Podcast, Patrick is joined by Giles Yeo, geneticist and author of Gene Eating: The Science of Obesity and the Truth About Dieting and Why Calories Don't Count: How We Got the Science of Weight Loss Wrong. Giles and Patrick discuss the genetic, neural, and evolutionary drivers of obesity, the advancements in safe and effect…
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OpenAI to Remain Non-Profit, OpenAI to Buy Windsurf, Jon Voight's Plan to Fix Hollywood, Kelvin Yu, James Blom, Santi Ruiz, Jacob Kimmel, Fil Aronshtein
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The Legacy of Warren Buffett, Bucky Moore, Katherine Boyle, Aditya Agarwal, Molly O'Shea, Augustus Doricko
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a16z Rebranding, Worldcoin Launches in U.S., Judge Delivers Blow to Apple's Business Model, Tesla Price Falls Amid Reporting of Elon's Replacement
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LIVE FROM HILL & VALLEY: Jacob Helberg, Delian Asparouhov, Christian Garrett, Josh Wolfe, Eric Glyman, Karim Atiyeh, Mike Solana, Keith Rabois, Qasar Younis, Shaun Maguire, Sampriti Bhattacharyya, David ...
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EP 185: From newborn screening to lifelong data in an evolving genomics landscape with Madhuri Hegde of Revvity
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40:44This week on The Genetics Podcast, Patrick is joined by Madhuri Hegde, SVP and Chief Scientific Officer of Revvity. They discuss Revvity’s advances in ultra-rapid clinical-grade sequencing, opportunities, challenges, and global inequities in newborn screening, and the dilemma of resequencing versus long-term data storage. Show Notes: 0:00 Intro to …
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Live from Washington, DC: Will Manidis, Analysis of Intel Earnings, Analysis of TSMC Earnings, Amazon Denies Plans to Display Tariff Impact at Checkout
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Earnings Season, Magnificent Seven off to Worst Starts Since 2022, The Group Chats That Changed America, Huawei Aims to Match NVIDIA with New AI Chip, Tech's Favorite Microconferences and Private Summits ...
1:18:45
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Karri Saarinen, Sean Frank, Semil Shah, Dan Lorenc, Google's Earnings Power Holding Up Well, Intel Says Layoffs are in Store, The Relationship Between Netflix and The NFL, Elon's Friends Sell Access to ...
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2:46:29Karri Saarinen is the co-founder and CEO of Linear, a popular issue tracking and project management tool. Previously, he was a design lead at Airbnb, focusing on design systems and product development. @karrisaarinen Sean Frank is the CEO of Ridge, best known for the Ridge Wallet and expanding the brand into a broader EDC (everyday carry) company. …
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Calley Means, Delian Asparouhov, Leif Abraham & Jannick Malling, Alfred Wahlforss & Florian Juengermann, Saman Farid, Erik Palitsch, Netflix's Growth Plans Post Earnings, AMD's Plan to Beat NVIDIA
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EP 184: Rethinking speed and scale in clinical genomics with Euan Ashley of Stanford University
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42:56This week on The Genetics Podcast, Patrick is joined by Dr. Euan Ashley, Chair of the Department of Medicine at Stanford, founder of various biotech companies, and author of The Genome Odyssey: Medical Mysteries and the Incredible Quest to Solve Them. They discuss Euan’s groundbreaking work on ultra-rapid genome sequencing and how widespread sequen…
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Bridgit Mendler, Aravind Srinivas, Ted Feldmann, Karol Hausman & Lachy Groom, Sam Lessin, Kevin Systrom Says Meta Denied Instagram Resources
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Jacob Peters, Logan Kilpatrick, Roy Lee, Erik Torenberg, Jack Whitaker, Trump Laying Groundwork to Blame Powell for Downturn, Boeing to Sell Some of Its Navigation Business in $10.55B Deal, History of ...
2:57:19
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David Tisch, Mike Vernal, Edward Mehr, Will Brown, Stocks Mogged as Trade War Escalates, R.I.P. Pope Francis, How Prior Beliefs Distort Perceptions, Why Robots Still Can't Make Nikes, Robots Join Chinese ...
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David Senra, Nichole Wischoff, Daniel Yanisse, Ryan Sandler, History of "Golden Dome", Johnson & Johnson Pivots AI Strategy, Google & Meta Facing Legal Threats, EU Delayed Penalizing Apple & Meta Platforms ...
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Shyam Sankar, Delian Asparouhov, Ian Brooke, Gaurav Misra, Ahti Heinla, Daniel Singer, Adam Kovacevich, OpenAI Unveils New Reasoning Models, OpenAI in Talks to Acquire Windsurf for $3B
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EP 183: Rewriting the Rules for Ultra-Rare Diseases with Kent Rogers of EveryONE Medicines
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40:07This week on The Genetics Podcast, Patrick is joined by Kent Rogers, Chief Executive Officer at EveryONE Medicines. They discuss Kent’s journey across every side of the desk in the drug discovery space, EveryONE Medicines’ efforts to develop antisense oligonucleotides for ultra-rare diseases, and the need to adapt regulatory models for n-of-1 thera…
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Ali Partovi, Tim Fist, China's Semiconductor Evolution, NVIDIA's China Business
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Aaron Ginn, John Gedmark, Jordan Schneider, History of U.S. China Relations, OpenAI Explores Social Network Arena
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Tyler Cowen, Ara Kharazian, Jan Sramek, Nvidia to Make AI Supercomputers in the U.S., What Apple Has at Stake in China, Trump Alters Course on Tariffs
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Blake Resnick, Ian Cinnamon, Zach Weinberg, Jen Bucci, Paul Mikesell, Rylan Hamilton, Zach Long, Formula One
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Figure AI in WSJ, Russell d'Sa, Quaid Walker, Alex Dhillon, Robin Langtry, Everett Randle, Keller Rinaudo Cliffton
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EP 182: Demystifying genetic counseling with Matt Burgess
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48:28This week on The Genetics Podcast, Patrick is joined by Matt Burgess, genetic counselor, host of the Demystifying Genetics podcast, and Adjunct Professor at Bay Path University. They discuss the evolution of genetic counseling, ethical challenges in gene therapy, and Matt’s experiences with his podcast. Show Notes: 0:00 Intro to The Genetics Podcas…
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Markets Surge, Apple's Tariff Strategy, Tracy Alloway, Justin Lopas, Paul Klein, Akshay Krishnaswamy
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Meta AI Deep Dive, Jeff Huber, Sheel Mohnot, Leif Abraham, Samuel Hammond, Víctor Perez, Jai Malik, Pratap Ranade
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Keith Rabois, Logan Bartlett, Shane Arnott, Flo Crivello, Rahul Sonwalkar, Bryce Roberts, Ben Thompson on Trade, Tariffs, and Tech, Anduril Releases Coppherhead
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Could AI Takeover by 2027, David Perell, Morgan Housel, Aviok Kohli, Virgílio "V" Bento, Kirsten Green, Shawn Wang, Ryan Hudson
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Trump's Tariffs, Market Crash, Zachary Perret, Scott Wu, Sam D'Amico, Peter Goldsborough, Nathan Mintz, Michael Laframboise, Fil Aronshtein, Chris Power, Brandon Tseng, Akhil Iyer
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EP 181: Transforming frustration into breakthroughs in gene therapy with Salvador Rico of Encoded Therapeutics
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45:30This week on The Genetics Podcast, Patrick is joined by Salvador Rico, Chief Medical Officer at Encoded Therapeutics. They discuss Salvador’s journey into drug development, his work on gene therapy for X-linked myotubular myopathy, and fundamental challenges and exciting advances in the genetics field. Show Notes: 0:00 Intro to The Genetics Podcast…
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Ryan Petersen, James Cadwallader, Quaid Walker, Sarah Guo, Nicholas Harris, Raunaq Singh, Deel Spy Scheme, Tesla Deliveries Drop
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3:13:56TBPN.com is made possible by: Ramp - https://ramp.com Eight Sleep - https://eightsleep.com/tbpn Wander - https://wander.com/tbpn Public - https://public.com AdQuick - https://adquick.com Bezel - https://getbezel.com Numeral - https://www.numeralhq.com Polymarket - https://polymarket.com/ Follow TBPN: https://TBPN.com https://x.com/tbpn https://open…
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David Senra, Samir Chaudry, Aidan McLaughlin, Will Depue, SoftBank's $40B OpenAI Deal, Inside Sam Altman's Firing, Luxury Show-Jumping
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Aaron Levie, Alexis Ohanian, R.J. Halperin, Cristóbal Valenzuela, David Zagaynov, Sam Lessin, xAI Merges with X, Isomorphic Labs Raises $600M
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Dwarkesh Patel, Nadia Asparouhova, Augustus Doricko, Casey Handmer, Ishan Mukherjee, Mike Knoop, Trump Pardons Milton, Coreweave IPO Winners
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Defense Tech Day, Delian Asparouhov, Dhruva Rajendra, Steven Simoni, Chris Power, Aaron Slodov, AJ Piplica, Connor Love, Cameron McCord
3:05:59
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EP 180: From a consulting project to a biotech start-up with Leeland Ekstrom of Nashville Bio
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41:24This week on The Genetics Podcast, Patrick is joined by Leeland Ekstrom, CEO and co-founder of Nashville Bio. They discuss how Leeland went from being a consultant on a project for Vanderbilt University to a co-founder of a start-up and the unique aspects of NashBio’s clinical and genetic database. Show Notes: 0:00 Intro to The Genetics Podcast 00:…
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Studio Ghibli, Andrew Reed, Rob Mohr, Tanay Jaipuria, Immad Akhund, Steven Schwartz, Jeremy Levine, Anthropic Copyright Dispute
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Darshan Shanker, Pavel and Delian Asparouhov, Alex Konrad, Jordan Schneider, Willem Van Lancker, Christian Garrett, @carrynointerest, 11x Controversy, Robo Arms
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Saratoga Water, Amjad Masad, Guillermo Rauch, Lulu Cheng Meservey, Kian Sadeghi, Vercel and Replit
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Shaun Maguire, Harry Stebbings, Blake Anderson, Sean Frank, Adam Ryan, Connor MacDonald, Perplexity $18B Valuation, Tornado Cash
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David Senra, Delian Asparouhov, Brendan Foody, Jake Adler, Apple Makes Moves, Hims & Hers
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EP 179: Redefining rare disease realities with Sharon Terry of the Genetic Alliance
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42:08This week on The Genetics Podcast, Patrick is joined by Sharon Terry, President & CEO of Genetic Alliance. They discuss how Sharon established a layperson-led biobank, her long-term work on rare diseases and patient advocacy, and her program to bring genetic technology to patients in low- to middle-income countries. Show Notes: 0:00 Intro to The Ge…
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