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EP 186: Unpacking the science and myths around obesity and health with geneticist and author Giles Yeo

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Manage episode 481361036 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.

This week on The Genetics Podcast, Patrick is joined by Giles Yeo, geneticist and author of Gene Eating: The Science of Obesity and the Truth About Dieting and Why Calories Don't Count: How We Got the Science of Weight Loss Wrong. Giles and Patrick discuss the genetic, neural, and evolutionary drivers of obesity, the advancements in safe and effective obesity drugs, and the narratives around calorie counting and ultra-processed foods.

Show Notes:

0:00 Intro to The Genetics Podcast

00:59 Welcome to Giles and an overview of recent advances in obesity treatment

04:28 How incretin-based therapies such as GLP-1 receptor agonists have enhanced our understanding of obesity

06:46 Unexpected effects of GLP-1-based therapies on neurodegenerative disease and addiction

09:39 Relative safety and potential side effects of GLP-1-based therapies

11:18 The gap in genetic characterization of individuals with different responses to GLP-1-based treatment

13:10 Competition and demand in the market for obesity drugs

15:46 Targeting comorbidities and genetic and neural components of obesity

19:09 Evolutionary aspects of obesity and how modern world factors can increase risk

24:26 The role of choice in dietary habits

26:29 The spectrum of genetic influences on body weight

29:50 Next frontiers in obesity research and opportunities from genetic advances

32:52 The controversial premise of Giles’ second book on why calorie counting misses the point in improving diet and health

37:43 Giles’ nuanced perspective on ultra-processed foods

44:46 Future avenues for Giles’ research, including mapping genetics and neural circuits underlying obesity

46:05 Giles’ writing process and plans to write a third book

48:55 Closing remarks

  continue reading

215 episodes

Artwork
iconShare
 
Manage episode 481361036 series 2631947
Content provided by Sano Genetics. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Sano Genetics or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.

This week on The Genetics Podcast, Patrick is joined by Giles Yeo, geneticist and author of Gene Eating: The Science of Obesity and the Truth About Dieting and Why Calories Don't Count: How We Got the Science of Weight Loss Wrong. Giles and Patrick discuss the genetic, neural, and evolutionary drivers of obesity, the advancements in safe and effective obesity drugs, and the narratives around calorie counting and ultra-processed foods.

Show Notes:

0:00 Intro to The Genetics Podcast

00:59 Welcome to Giles and an overview of recent advances in obesity treatment

04:28 How incretin-based therapies such as GLP-1 receptor agonists have enhanced our understanding of obesity

06:46 Unexpected effects of GLP-1-based therapies on neurodegenerative disease and addiction

09:39 Relative safety and potential side effects of GLP-1-based therapies

11:18 The gap in genetic characterization of individuals with different responses to GLP-1-based treatment

13:10 Competition and demand in the market for obesity drugs

15:46 Targeting comorbidities and genetic and neural components of obesity

19:09 Evolutionary aspects of obesity and how modern world factors can increase risk

24:26 The role of choice in dietary habits

26:29 The spectrum of genetic influences on body weight

29:50 Next frontiers in obesity research and opportunities from genetic advances

32:52 The controversial premise of Giles’ second book on why calorie counting misses the point in improving diet and health

37:43 Giles’ nuanced perspective on ultra-processed foods

44:46 Future avenues for Giles’ research, including mapping genetics and neural circuits underlying obesity

46:05 Giles’ writing process and plans to write a third book

48:55 Closing remarks

  continue reading

215 episodes

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