Best Muscle Temple Podcasts (2025)

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Mitochondrial Transfer, Obesity & Immune-Metabolism Interactions | Jon Brestoff | 261 56:56

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1h ago56:56

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Send us a text How mitochondria travel between cells and how this hidden communication shapes metabolism, immunity, and even potential therapies. Episode Summary: Dr. Jon Brestoff talks about mitochondrial dynamics inside cells, their transfer between unrelated cells (distinct from inheritance during division), and its roles in adipose tissue commu…

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Energy Resistance Principle in Life, Healing & Disease | Martin Picard & Nirosha Murugan | 260 2:09:30

5d ago2:09:30

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Send us a text A biophysical rethink of life, health, and disease through the lens of the Energy Resistance Principle (ERP). Episode Summary: A reframe of biology as energy flow through resistance rather than mere molecular machinery, introducing the Energy Resistance Principle (ERP): life requires a Goldilocks balance of electron flow from food to…

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Menstrual & Lunar Cycle Synchrony, Circadian Rhythms | Charlotte Förster | 259 57:47

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Send us a text How artificial light impacts female menstrual cycles and their relationship to lunar cycles of the moon. Summary: Dr. Förster talks about how biological clocks, including circadian, tidal, lunar, and annual cycles, regulate behaviors in various species, with a focus on lunar cycle effects on human menstrual cycles. They explore histo…

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Evolution of Bipedality, Human Pelvis, Muscle & Brain | Terence Capellini | 258 1:22:18

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Send us a text The genetic & developmental changes behind bipedalism & human anatomy. Wide release date: October 15, 2025. Episode Summary: Dr. Terence Capellini talks about the evolution of bipedalism in humans, exploring when and why it emerged, the anatomical changes required, and the genetic mechanisms behind these adaptations. They discuss how…

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Sleep, Mitochondrial Metabolism & Oxidative Stress | Gero Miesenbock | M&M 257 1:17:28

24d ago1:17:28

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Send us a text The biological roots of sleep are tied to mitochondrial metabolism. Episode Summary: Dr. Gero Miesenböck discusses the evolutionary and metabolic basis of sleep, exploring how mitochondrial energy production in neurons, particularly in fruit flies, drives the need for sleep to manage harmful byproducts like reactive oxygen species an…

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Bacterial Infection, Oral Hygiene, Atherosclerosis & Heart Disease | Pekka Karhunen | 256 39:07

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Send us a text The surprising link between oral bacteria and heart disease. Episode Summary: Dr. Pekka Karhunen explains the connection between oral bacteria, cholesterol, and cardiovascular disease, discussing how oxidized LDL cholesterol triggers inflammation in arteries, how bacteria from the mouth can infiltrate arterial plaques to form biofilm…

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Unlocking Energy: How Nutrition & Drugs Impact Your Mitochondria | Chris Masterjohn | M&M 255 2:06:15

1M ago2:06:15

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Send us a text How nutrition and medications impact mitochondrial health. Episode Summary: Dr. Chris Masterjohn talks about the intricate relationships between nutrition, prescription drugs, and mitochondrial health, discussing how molecules like acetaminophen and SSRIs affect the body beyond their intended purposes, particularly impacting inflamma…

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How Genes & Environment Shape Your Brain: ApoE, Alzheimer's & Space Radiation | Jacob Raber | 254 53:53

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Send us a text Genetic & environmental factors that affect brain health, including why people age faster in outer space. (Note: technical difficulties affected the audio quality of this recording somewhat) Episode Summary: Dr. Jacob Raber explains how apolipoproteins, particularly ApoE, influence brain health and disease risk; their role in cholest…

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Maternal Obesity, Immune System, Fatty Liver Disease & Epigenetics | Elvira Mass | 253 1:13:05

1M ago1:13:05

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Send us a text How maternal obesity epigenetically reprograms liver metabolism in offspring, predisposing them to metabolic disease. Episode Summary: Dr. Elvira Mass talks about macrophages, specialized immune cells that vary by tissue and play crucial roles beyond fighting infections, such as supporting organ function; Kupffer cells (liver macroph…

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Scarring, Fibrosis, Oxidative Stress, and Psilocybin & Aging | Louise Hecker | 252 59:57

2M ago59:57

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Send us a text Aging, tissue repair, and the longevity benefits of psilocin. Episode Summary: Dr. Louise Hecker discusses her research on tissue repair and regeneration, explaining how fibroblasts drive wound healing by forming scar tissue but fail to resolve properly with age, leading to fibrotic diseases like pulmonary fibrosis and liver cirrhosi…

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Protein Restriction & Liver Hormones: Appetite, Brain, Behavior | Chris Morrison | 251 1:40:18

2M ago1:40:18

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Send us a text The effects of protein restriction on metabolism, liver hormones, brain, and behavior. Episode Summary: Dr. Christopher Morrison talks about how animals sense and prioritize nutrients like protein, discussing defense mechanisms for essentials such as oxygen, water, sodium, and energy; the brain's role in detecting protein deprivation…

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Cognition, Form, Regeneration & Metaphysics: Does Biology Arise From Math? | Michael Levin | 250 1:08:34

2M ago1:08:34

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Send us a text Support the show Affiliates: Seed Oil Scout: Find restaurants with seed oil-free options, scan food products to see what they’re hiding, with this easy-to-use mobile app. KetoCitra—Ketone body BHB + electrolytes formulated for kidney health. Use code MIND20 for 20% off any subscription (cancel anytime) Lumen device to optimize your m…

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Fructose, Microglia, Anxiety & Brain Development | Justin Perry | 249 1:39:43

2M ago1:39:43

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Send us a text Cellular clean up by immune cells and how early-life fructose exposure leads to neurodevelopmental problems. Episode Summary: Dr. Justin Perry talks about the body's constant cellular turnover—about 3 million cells die per second in adults (double in children and women)—handled by phagocytes like macrophages that engulf and digest de…

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Autism, Acetaminophen (Tylenol) & Oxidative Stress | William Parker | 248 1:41:49

2M ago1:41:49

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Send us a text The potential link between acetaminophen (Tylenol) and autism, with a surprise phone call from RFK partway through. Episode Summary: Dr. William Parker talks about autism spectrum disorder (ASD), its rising prevalence since the 1980s, and the controversial hypothesis that acetaminophen exposure in susceptible infants and children tri…

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Cholesterol: Immune Benefits, Heart Health, Statins & Research Malpractice | Uffe Ravnskov | 247 55:09

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Send us a text Wide release date: August 25, 2025 Episode Summary: Dr. Uffe Ravnskov talks about his decades-long career challenging the idea that high cholesterol causes heart disease, discussing LDL's protective role in the immune system by binding to bacteria, the harms and biases in statin research influenced by pharmaceutical companies, eviden…

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Appendix, Gut Worms, Allergies & Autoimmunity | William Parker | 246 1:19:56

3M ago1:19:56

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Send us a text The appendix's hidden role and how "good" parasites like helminths shape immune health. Episode Summary: Dr. William Parker discusses gut anatomy, the appendix's role in harboring beneficial bacterial biofilms and immune tissue, and how modern hygiene depletes helminths (intestinal worms), causing immune overreactions like allergies,…

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Cannabinoid System: Metabolism, Evolution & Energy Storage | Giovanni Marsicano | 245 1:44:55

3M ago1:44:55

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Send us a text What is the core evolved function of the endocannabinoid system? Episode Summary: Dr. Giovanni Marsicano is a neuroscientist based in Bordeaux, France, where he leads a research group at INSERM focusing on the endocannabinoid system. About the guest: Giovanni Marsicano, PhD discusses the endocannabinoid system, starting with its core…

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Seed Oils & Heart Disease: Oxidized LDL, Cholesterol, Fat & Cardiology | Tucker Goodrich | 244 1:39:25

3M ago1:39:25

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Send us a text Overview and alternative interpretation to the mainstream view on how dietary fat and cholesterol relate to cardiovascular disease. Episode Summary: Tucker Goodrich is an engineer by training who has become a prominent independent researcher and blogger on nutrition and metabolic health, focusing on the harms of seed oils and polyuns…

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Evolution & Variation in Human Diet, Energy Expenditure & Metabolism | Herman Pontzer | 243 1:49:42

3M ago1:49:42

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Send us a text Human metabolism, primate evolution, and modern health challenges with evolutionary anthropologist Herman Pontzer. Episode Summary: Anthropologist Dr. Herman Pontzer discusses human evolution and metabolism, comparing humans to primates like chimps and gorillas to explain our higher energy use, bigger brains, and longer lives despite…

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Sunlight: Cosmology, Energy Metabolism & the Physics of Life | Robert Fosbury | 242 2:13:07

3M ago2:13:07

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Send us a text The deep connection between sunlight and life, from the scale of the cosmos to the quantum. Episode Summary: Astrophysicist Dr. Robert Fosbury discusses the sun's characteristics as a star, its analogies to living systems via entropy and complexity, and Erwin Schrödinger's insights on life as order-maintaining entities; he explores h…

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Synapse Energetics & Fat Metabolism in the Brain | Timothy Ryan | 241 1:25:59

3M ago1:25:59

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Send us a text How brain synapses work and fuel themselves with fat. Episode Summary: Dr. Timothy Ryan talks about the high energy costs of synapses, the role of mitochondria and glycolysis, and challenge the long-held view that the brain relies solely on glucose by discussing new evidence that neurons burn fats from lipid droplets for fuel, especi…

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Microbiome as a Modifiable Organ System | Eugene Chang | 240 1:28:12

4M ago1:28:12

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Send us a text Episode Summary: Dr. Eugene Chang talks about the microbiome’s role as a vital organ, the impacts of antibiotics and Western diets on microbial health, and strategies for restoring a damaged microbiome through diet and fecal microbial transplants. They delve into microbiome dysbiosis, its links to modern diseases, and Chang’s researc…

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Sleep Duration, Sleep Timing & Short-Sleepers | Ying-Hui Fu | 239 54:06

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Send us a text The genetics of sleep duration and sleep timing. Episode Summary: Dr. Ying-Hui Fu discusses her research on the genetics of sleep, focusing on natural short sleepers who thrive on 4-6 hours of sleep and the heritability of sleep traits like duration and timing. She explores how sleep efficiency, rather than just duration, may explain…

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Hormones, Endocrine Disruptors & the Fate of Modern Liberal Society | Charles Cornish-Dale | 238 1:33:58

4M ago1:33:58

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Send us a text A blend of biology, philosophy, and history exploring how hormones and endocrine disruptors affect social behavior and society. Episode Summary: Dr. Charles Cornish-Dale discusses the decline of masculinity in modern society, linking it to falling testosterone levels, environmental endocrine disruptors, and the limitations of liberal…

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Circadian Biology: Genetics, Behavior, Metabolism, Light, Oxygen & Melatonin | Joseph Takahashi | M&M 237 1:52:33

4M ago1:52:33

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Send us a text How our biological clocks shape biology from the molecular to behavioral level. Episode Summary: Dr. Joseph Takahashi discusses circadian rhythms, exploring their biological basis, from molecular mechanisms to their impact on metabolism and health; the discovery of circadian clock genes; role of the suprachiasmatic nucleus, and how l…

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Cell Biology: Cytoskeleton, Self-Assembly & Self-Organization, Wound Healing | Bill Bement | 236 1:31:14

4M ago1:31:14

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Send us a text Cellular self-organization, cytoskeleton dynamics, and membrane wound healing. Episode Summary: Cell Biologist Dr. Bill Bement explains the dynamic world of the cell cortex, discussing how actin filaments and microtubules drive processes like cell division and wound healing through self-assembly and self-organization; energy dynamics…

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Computational Neuroscience, Machine Learning vs. Biological Learning, Large Language Models | Marius Pachitariu | 235 1:50:04

4M ago1:50:04

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Send us a text How brains compute and learn, blending neuroscience with AI insights. Episode Summary: Dr. Marius Pachitariu discusses how the brain computes information across scales, from single neurons to complex networks, using mice to study visual learning. He explains the differences between supervised and unsupervised learning, the brain’s hi…

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Brain Fat: Dietary PUFAs, Cannabinoids, Fatty Acid Binding Proteins, Anxiety & Mood | Steven Laviolette | 234 1:12:53

5M ago1:12:53

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Send us a text How dietary fats and cannabinoids shape brain function and mental well-being. Episode Summary: Dr. Steven Laviolette discusses the role of lipids, particularly endocannabinoids and fatty acids, in brain signaling and mental health, discussing how dietary omega-3 and omega-6 imbalances, prenatal THC exposure, and fatty acid binding pr…

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Feel the Burn: Seed Oils, Memes & Oxidative Stress | Brian Kerley | 233 2:10:38

5M ago2:10:38

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Send us a text Are seed oils really driving chronic disease (and sunburns), or is it hype? Episode Summary: Dr. Brian Kerley talks about the health impacts of seed oils, their high omega-6 fatty acid content, and their role in chronic diseases through mechanisms like lipid peroxidation and oxidative stress. They explore how these industrially proce…

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SSRIs, Sexual Dysfunction, Suicide & Mass Shootings, How FDA Works | David Healy | 232 2:10:09

5M ago2:10:09

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Send us a text A critique of SSRIs and pharma’s influence on medicine, including SSRI-induced sexual dysfunction, suicidality, and violence. Long Summary: Dr. David Healy critiques modern medicine, focusing on SSRIs and psychiatric medicine, including: how pharmaceutical companies manipulate clinical trial data, ghostwrite studies, and influence me…

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Psychedelic Chemistry, Magic Mushrooms, Kratom, Gray Market Research Chemicals, Vape Shops | Andrew Chadeayne | 231 1:38:37

5M ago1:38:37

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Send us a text Episode Summary: Dr. Andrew Chadeayne discusses the chemistry of psilocybin and other psychedelics, their potential therapeutic applications, and the challenges of commercializing them in a shifting biotech market. The conversation delves into the complexities of magic mushroom composition, debunking myths like "lemon tekking," and u…

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Psilocybin & MDMA: Inflammation, Stress & Brain-Body Communication | Michael Wheeler | 230 1:09:38

6M ago1:09:38

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Send us a text Episode Summary: Dr. Michael Wheeler talks about neuroimmune interactions, exploring how the immune system and brain communicate, particularly through the blood-brain barrier and meninges; how chronic stress and inflammation can alter brain circuits, contributing to mood disorders like depression; how drugs like psilocybin and MDMA m…

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Linoleic Acid, Seed Oils, mTOR & Breast Cancer | Nikos Koundouros & John Blenis | 229 1:47:18

6M ago1:47:18

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Send us a text Episode Summary: New research on how dietary fats, particularly omega-6 fatty acids like linoleic acid, influence triple-negative breast cancer progression by activating the mTOR pathway, a key regulator of cell growth; role of the FABP5 protein in enhancing cancer cells’ sensitivity to omega-6 fats; differences between breast cancer…

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Rhythms, Memory, Time, Place, Representation & the Brain | György Buzsáki | 228 1:48:30

6M ago1:48:30

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Send us a text Episode Summary: Dr. Gyorgy Buzsaki discusses the hippocampus’s role beyond memory and spatial navigation, delving into its broader functions in cognition, action planning, and brain-body interactions; how hippocampal rhythms, like sharp wave ripples, influence memory consolidation, glucose regulation, and metabolic health, challengi…

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Biophysics of Life: Biophotons, Light, Quantum Biology, Regeneration & Cancer | Nirosha Murugan | 227 1:39:21

6M ago1:39:21

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Send us a text The biophysics of life, exploring how light & energy shape biology, with biophysicist Dr. Nirosha Murugan. Episode Summary: Dr. Murugan discusses the role of biophysics in biology, focusing on how light, particularly biophotons emitted by cells, influences processes like wound healing, neural activity, and cancer detection; how micro…

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Psychedelics & Cerebral Cortex: Neuroplasticity, Psilocybin, Ketamine | Alex Kwan | 226 1:17:35

6M ago1:17:35

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Send us a text Short Summary: Dr. Alex Kwan unpacks the latest neuroscience research on how psychedelics like ketamine & psilocybin reshape the brain. About the guest: Alex Kwan, PhD, is an associate professor of biomedical engineering at Cornell University. His lab employs advanced imaging to study how psychedelics and other drugs affect the mamma…

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Nutrition Epidemiology: Fake Science? | John Speakman | 225 1:05:49

6M ago1:05:49

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Send us a text Short Summary: The flaws of nutrition epidemiology with Dr. John Speakman About the guest: John Speakman, PhD is a professor at the University of Aberdeen and runs a lab in Shenzhen, China, focusing on energy balance, obesity, and aging. Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone o…

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Cancer Biology: Metabolism, Mitochondria & Energy | Thomas Seyfried | 224 1:52:21

6M ago1:52:21

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Send us a text Short Summary: Cancer’s metabolic roots with Dr. Thomas Seyfried. About the guest: Thomas Seyfried, PhD is a professor of biology at Boston College. He has researched cancer metabolism, epilepsy, and lipid biochemistry for over 40 years. Note: Podcast episodes are fully available on the M&M Substack and YouTube. Transcript and other …

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Ketogenic Diet: Cholesterol, Plaque & Heart Heart | Matthew Budoff | 223 58:44

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Send us a text Short Summary: Heart health and the ketogenic diet, with expert insights from a cardiologist and researcher. About the guest: Matthew Budoff, MD, is a preventive cardiologist and professor of medicine at UCLA School of Medicine. Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube…

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Genetics & Neurobiology of Obesity: Hypothalamus, Leptin, Gut Hormones, Weight Loss Drugs | Giles Yeo | 222 1:33:39

7M ago1:33:39

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Send us a text Short Summary: The science of obesity and appetite regulation, blending genetics and neurobiology with practical insights About the guest: Giles Yeo, PhD is a professor of molecular neuroendocrinology at the University of Cambridge. He leads a lab studying obesity and appetite regulation. Note: Podcast episodes are fully available to…

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Regenerative Energy & the Light Inside You | Jack Kruse | 221 2:26:57

7M ago2:26:57

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Send us a text Short Summary: A mind-bending dive into evolutionary biology and health through a biophysicist’s lens, with Dr. Jack Kruse delivering provocative insights about biology, medicine, and health. About the guest: Jack Kruse, MD, is a neurosurgeon known for integrating biophysics into medicine. He challenges conventional biochemistry with…

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Cell Death, Oxidative Stress, PUFAs & Antioxidants | Pamela Maher | 220 1:40:07

7M ago1:40:07

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Send us a text Short Summary: A deep dive into the science of oxidative stress, antioxidants, aging, and neurodegenerative diseases like Alzheimer’s. About the guest: Pamela Maher, PhD is a professor at the Salk Institute in San Diego, California, with a focus on neurodegenerative diseases, oxidative stress, and antioxidants. Note: Podcast episodes…

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Shamanism, Human Culture & the Evolution of Religion | Manvir Singh | 219 1:44:18

7M ago1:44:18

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Send us a text Short Summary: A detailed examination of shamanism with anthropologist Manvir Singh, blending evolutionary theory and vivid storytelling. About the guest: Manvir Singh, PhD is an anthropologist at the University of California, Davis. His new book, "Shamanism: The Timeless Religion," comes out on May 25, 2025. Note: Podcast episodes a…

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Chemical Exposures, Neurodegenerative Disease & Exposomics | Gary Miller | 218 1:33:06

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Send us a text Short Summary: How environmental chemical exposures affect neurodegenerative disease and health. About the guest: Gary Miller, PhD is a Professor of Environmental Health Sciences at Columbia University. His research bridges pharmacology, toxicology, and neuroscience to explore neurodegeneration, particularly Parkinson’s and Alzheimer…

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Communication & Social Cognition in Elephants & Animals | Mickey Pardo | 217 1:39:43

7M ago1:39:43

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Send us a text Short Summary: Do elephants and other animals have language-like abilities, such as the ability to use individual names to refer to themselves and others? About the guest: Michael Pardo, PhD studies animal behavior at Cornell University, where he focused on animal communication and cognition. His work includes extensive field researc…

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Can Aspirin Prevent Cancer Metastasis? | Rahul Roychoudhuri | 216 1:26:48

7M ago1:26:48

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Send us a text Short Summary: The science of cancer and immunity with Dr. Roychoudhuri, blending cutting-edge research with everyday implications like aspirin’s role in fighting tumor metastasis. About the guest: Rahul Roychoudhuri, PhD is a Professor of Cancer Immunology at the University of Cambridge. His research bridges basic science and clinic…

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Cancer Metabolism: Sugar, Fructose, Lipids & Fasting | Gary Patti | 215 1:45:17

8M ago1:45:17

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Send us a text How dietary fructose affects the growth rate of cancer. About the guest: Gary Patti, PhD is a professor at Washington University in St. Louis, holding appointments in chemistry, medicine, and genetics Episode Summary: Nick Jikomes talks to Dr. Patti, exploring how cancer cells metabolize sugars like glucose and fructose, focusing on …

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Gut Microbiome Plasticity | Peter Turnbaugh | 214 41:19

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Send us a text Short Summary: How diet shapes the gut microbiome and impacts health, with microbiologist Dr. Peter Turnbaugh breaking down the complex science. About the guest: Peter Turnbaugh, PhD is a professor of microbiology and immunology at the University of California, San Francisco, where he leads a lab studying the gut microbiome’s role in…

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Causes of Diabetes: Insulin, Mitochondria, Genetics, Metabolism | Scott Soleimanpour | 213 49:04

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Send us a text Short Summary: The science of diabetes with Dr. Scott Soleimanpour, blending personal insights and cutting-edge research that gets into mitochondrial biology and more. About the guest: Scott Soleimanpour, MD, is a physician-scientist at the University of Michigan, where he runs a lab studying pancreatic beta cell biology and mitochon…

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How Science Works: Meta-Research, Publishing, Reproducibility, Peer Review, Funding | John Ioannidis | 212 54:02

8M ago54:02

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Send us a text Short Summary: A rare, insider’s look at the messy realities of scientific research with Stanford’s Dr. John Ioannidis. The good, the bad, and the ugly about how scientific research actually works. About the guest: John Ioannidis, MD, PhD is a professor at Stanford University in medicine, epidemiology, population health, and biomedic…