Search a title or topic

Over 20 million podcasts, powered by 

Player FM logo
Artwork

Content provided by Nick Jikomes. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Nick Jikomes or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
Player FM - Podcast App
Go offline with the Player FM app!

Feel the Burn: Seed Oils, Memes & Oxidative Stress | Brian Kerley | 233

2:10:38
 
Share
 

Manage episode 488070117 series 2846067
Content provided by Nick Jikomes. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Nick Jikomes or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.

Send us a text

Are seed oils really driving chronic disease (and sunburns), or is it hype?

Episode Summary: Dr. Brian Kerley talks about the health impacts of seed oils, their high omega-6 fatty acid content, and their role in chronic diseases through mechanisms like lipid peroxidation and oxidative stress. They explore how these industrially processed oils may contribute to conditions like heart disease and obesity, discuss the challenges of studying their long-term effects, and highlight the cultural and political dimensions of dietary trends.

About the guest: Brian Kerley, MD is a family medicine-trained hospitalist physician who gained online prominence as the "Seed Oil Disrespecter" through his meme account, raising awareness about the health risks of seed oils.

Discussion Points:

  • Seed Oils & Health Risks: Seed oils (e.g., soybean, corn, etc.) are high in omega-6 polyunsaturated fatty acids (PUFAs), linked to oxidative stress and lipid peroxidation, producing toxic compounds like 4-HNE and acrolein that damage cells.
  • Evolutionary Perspective: The high omega-6 levels in modern diets are evolutionarily novel, deviating from natural omega-6 to omega-3 ratios found in traditional diets, potentially exacerbating health issues across diverse populations.
  • Challenges with RCTs: Randomized controlled trials (RCTs) often fail to capture the long-term effects of seed oils due to the need for extended washout periods (up to 8 years) and the pervasive presence of omega-6 in modern food environments.
  • Cultural & Political Coding: Dietary trends like seed oil avoidance have become politically charged, with Kerley noting the polarization between institutional health narratives and alternative health communities, complicating public health discussions.
  • Personal Impact: Dr. Kerley’s focus on seed oils stems from personal experiences, including managing his daughter’s mitochondrial disorder, highlighting the personal stakes in dietary choices.

Related episode:

  • M&M 192: Seed Oils, Chronic Disease, Diet & Religious Cults, Mainstream Medicine vs. Independent Research | Tucker Goodrich

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack
Affiliates:

  • KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
  • Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
  • Readwise: Organize and share what you read. 60 days FREE through link
  • SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.
  • MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off

For all the ways you can support my efforts

  continue reading

237 episodes

Artwork
iconShare
 
Manage episode 488070117 series 2846067
Content provided by Nick Jikomes. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Nick Jikomes or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.

Send us a text

Are seed oils really driving chronic disease (and sunburns), or is it hype?

Episode Summary: Dr. Brian Kerley talks about the health impacts of seed oils, their high omega-6 fatty acid content, and their role in chronic diseases through mechanisms like lipid peroxidation and oxidative stress. They explore how these industrially processed oils may contribute to conditions like heart disease and obesity, discuss the challenges of studying their long-term effects, and highlight the cultural and political dimensions of dietary trends.

About the guest: Brian Kerley, MD is a family medicine-trained hospitalist physician who gained online prominence as the "Seed Oil Disrespecter" through his meme account, raising awareness about the health risks of seed oils.

Discussion Points:

  • Seed Oils & Health Risks: Seed oils (e.g., soybean, corn, etc.) are high in omega-6 polyunsaturated fatty acids (PUFAs), linked to oxidative stress and lipid peroxidation, producing toxic compounds like 4-HNE and acrolein that damage cells.
  • Evolutionary Perspective: The high omega-6 levels in modern diets are evolutionarily novel, deviating from natural omega-6 to omega-3 ratios found in traditional diets, potentially exacerbating health issues across diverse populations.
  • Challenges with RCTs: Randomized controlled trials (RCTs) often fail to capture the long-term effects of seed oils due to the need for extended washout periods (up to 8 years) and the pervasive presence of omega-6 in modern food environments.
  • Cultural & Political Coding: Dietary trends like seed oil avoidance have become politically charged, with Kerley noting the polarization between institutional health narratives and alternative health communities, complicating public health discussions.
  • Personal Impact: Dr. Kerley’s focus on seed oils stems from personal experiences, including managing his daughter’s mitochondrial disorder, highlighting the personal stakes in dietary choices.

Related episode:

  • M&M 192: Seed Oils, Chronic Disease, Diet & Religious Cults, Mainstream Medicine vs. Independent Research | Tucker Goodrich

*Not medical advice.

Support the show

All episodes, show notes, transcripts, and more at the M&M Substack
Affiliates:

  • KetoCitra—Ketone body BHB + potassium, calcium & magnesium, formulated with kidney health in mind. Use code MIND20 for 20% off any subscription (cancel anytime)
  • Lumen device to optimize your metabolism for weight loss or athletic performance. Code MIND for 10% off
  • Readwise: Organize and share what you read. 60 days FREE through link
  • SiPhox Health—Affordable at-home blood testing. Key health markers, visualized & explained. Code TRIKOMES for a 20% discount.
  • MASA Chips—delicious tortilla chips made from organic corn & grass-fed beef tallow. No seed oils or artificial ingredients. Code MIND for 20% off

For all the ways you can support my efforts

  continue reading

237 episodes

All episodes

×
 
Loading …

Welcome to Player FM!

Player FM is scanning the web for high-quality podcasts for you to enjoy right now. It's the best podcast app and works on Android, iPhone, and the web. Signup to sync subscriptions across devices.

 

Copyright 2025 | Privacy Policy | Terms of Service | | Copyright
Listen to this show while you explore
Play