JCO OP: Put Into Practice highlights new research published in JCO OP related to cancer care delivery, quality, disparities, access. Host Dr. Fumiko Chino, MD FASCO interviews thought leaders in oncology to give listeners practical knowledge that can be used in day-to-day practice along with solution-oriented discussions and care innovations.
…
continue reading
Oncology Knowledge Into Practice Podcasts
"Got Knowledge Doc" Podkast with Dr. RR Baliga The "Got Knowledge Doc" Podkast, hosted by Dr. Ragavendra R. Baliga, is a knowledge-driven platform designed for physicians and healthcare providers seeking to stay at the forefront of medical science and innovation. With a distinguished career in cardiovascular medicine and academic leadership, Dr. Baliga engages with leading experts to explore cutting-edge research, emerging technologies, and transformative insights in medicine and beyond. Eac ...
…
continue reading
In this bi-weekly podcast, cancer experts discuss game-changing topics in clinical oncology. Produced by Oncology Knowledge into Practice (www.onckip.com), this podcast will support and inform your practice in cancer management. This podcast is intended for healthcare professionals only. Funding information is available in each episode's notes. Access more free education today! Visit the OncKIP website, follow us on Twitter (@onckip ) or connect on LinkedIn. https://www.oncologyknowledgeinto ...
…
continue reading
1
PeerView Internal Medicine CME/CNE/CPE Video Podcast
PVI, PeerView Institute for Medical Education
PeerView (PVI) is a leading provider of high-quality, innovative continuing education (CME/CE/CPE and MOC) for clinicians and their interprofessional teams. Combining evidence-based medicine and instructional expertise, PeerView activities improve the knowledge, skills, and strategies that support clinical performance and patient outcomes. PeerView makes its educational programming and expert-led presentations and symposia available through its network of popular podcast channels to support ...
…
continue reading
Natural Medicine Journal's interviews with thought-leaders in the field of natural and integrative medicine dig deep into the most important topics in the field. Whether it's a one-on-one with top researchers in integrative medicine or a conversation with a practitioner about treating hard-to-tackle conditions, each episode promises to provide trusted, cutting-edge, evidence-based knowledge about natural medicine that you won't find anywhere else.
…
continue reading
1
Winning Against HFrEF π₯ππ Diagnose Early. Treat with GDMT. Follow Through
5:46
5:46
Play later
Play later
Lists
Like
Liked
5:46New Lancet Seminar on heart failure with reduced ejection fraction. ππ, this videocast walks listeners through the essentials of diagnosis, natriuretic peptides, imaging pathways, and the four foundational therapies shaping modern heart failure care. It's a clear, evidence-driven journeyβdesigned to inform, clarify, and elevate bedside practice. Tuβ¦
…
continue reading
1
David N. Lieberman, MD, PhD - Building Clinical Confidence in the Diagnosis and Multidisciplinary Management of Rett Syndrome
23:19
23:19
Play later
Play later
Lists
Like
Liked
23:19This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/QBS865. CME/AAPA cβ¦
…
continue reading
1
Bruce E. Sands, MD, MS - Fibrosis, Flares, and Forward Thinking in Inflammatory Bowel Disease Care: Unlocking the TL1A Axis
1:00:50
1:00:50
Play later
Play later
Lists
Like
Liked
1:00:50This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/WDQ865. CME/AAPA cβ¦
…
continue reading
1
Philip J. Mease, MD, MACR - Taking a New Look at Psoriatic Arthritis and Its Comorbidities Through the Lens of TYK2 Inhibition
1:14:12
1:14:12
Play later
Play later
Lists
Like
Liked
1:14:12This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/TEA8β¦
…
continue reading
1
Seeing CAD Clearly πβ€οΈ: Plaque, Perfusion, Prognosis πΈππ
6:20
6:20
Play later
Play later
Lists
Like
Liked
6:20ππ Chronic Coronary Artery Disease: Seeing What Matters Before It Hurts Just finished reviewing the 2025 Lancet paper on contemporary non-invasive imaging for chronic CAD, and the message is striking: how we see the heart shapes how well we save it. From CT angiography that unmasks non-obstructive plaque π₯οΈβ‘οΈπ« to stress PET/CMR that maps true ischeβ¦
…
continue reading
1
Dr RR Baliga's Philosophical Discourses: David Hume (Scotland, 1711β1776 CE) β Skepticism and Empiricism
3:25
3:25
Play later
Play later
Lists
Like
Liked
3:25Exploring David Hume π§ β¨ Just revisited David Hume's extraordinary contributions to modern thought β a reminder of how deeply empiricism, skepticism, and the science of human nature shape our intellectual world. His insights on causation, the limits of reason, and the power of moral sentiment continue to resonate across philosophy, psychology, econoβ¦
…
continue reading
1
Heart Failure Rising π | Risks Rewired π | America's 35-Year Shift πΊπΈ
4:42
4:42
Play later
Play later
Lists
Like
Liked
4:42The U.S. heart failure landscape is transformingβand fast. π«π A new JACC analysis reveals a 35-year shift from ischemic to metabolic drivers of heart failure, with obesity, dysglycemia, and chronic kidney disease rising sharply, even as blood pressure, cholesterol, smoking, and myocardial infarction decline. πβοΈ These trends demand a new generationβ¦
…
continue reading
1
Clocks, Clues, and Clarity β³π¬π§ β Decoding Organ-Specific Aging
3:20
3:20
Play later
Play later
Lists
Like
Liked
3:20π§¬β³ New Insights into Organ-Specific Aging! π§ β€οΈπ©Ί Just explored a remarkable Nature Aging study showing how organ-specific proteomic clocks can forecast disease, cognitive decline, and even longevity with impressive precision. These clocksβbuilt from >2,900 plasma proteinsβreveal that the brain, kidney, and arteries age on their own timelines, each cβ¦
…
continue reading
1
Vaccines. Viruses. Vital Signs. ππ¦ β€οΈ Adult Immunizations as Cardiovascular Prevention
4:29
4:29
Play later
Play later
Lists
Like
Liked
4:29Respiratory vaccines are not just infection-fightersβthey're cardiovascular protectors. ππ« The 2025 JACC Consensus reminds us that influenza, pneumococcal, COVID-19, RSV, and zoster vaccines reduce MI, HF decompensation, hospitalizations, and death in our most vulnerable patients. As clinicians, we hold the power to translate evidence into preventiβ¦
…
continue reading
1
Sun, Skin, Survival ππ§¬π‘οΈ β The Modern Landscape of Keratinocyte Carcinomas
3:02
3:02
Play later
Play later
Lists
Like
Liked
3:02The latest JAMA article on keratinocyte carcinomas πβa timely reminder that BCC and cSCC remain the world's most common cancers, with more than 5.4 million cases annually in the US alone . The review highlights essential updates in epidemiology, high-risk features, prevention, and evidence-based management, especially the role of sun protection, acβ¦
…
continue reading
1
Food In, Fire Out π½οΈπ₯βThe Leukotriene Story π§¬
4:48
4:48
Play later
Play later
Lists
Like
Liked
4:48π¨ Food Anaphylaxis: New Mechanisms Unveiled π½οΈπ§¬ A superb NEJM review highlights how cysteinyl leukotrienes act as gatekeepers in the gutβopening antigen passages, expanding mast cells, and amplifying the risk of oral anaphylaxis. The work elegantly bridges basic lipid biology with real-world food allergy challenges, and points toward new preventiveβ¦
…
continue reading
1
Cannabis: Promise, Peril, and Practice πΏβοΈπ§
5:07
5:07
Play later
Play later
Lists
Like
Liked
5:07πΏ What does the evidence really say about medical cannabis? A new JAMA review highlights a clear message: cannabis helps few conditionsβand harms may outweigh benefits for many. π Small benefit for nausea β‘ Moderate benefit for select pediatric seizures π Limited evidence for pain, insomnia, or psychiatric use β€οΈ Risks rise with high-potency producβ¦
…
continue reading
1
Dengue Blocked, Viral Load Dropped, Hope Unlocked--High-Dose Mosnodenvir Delivers πππ‘οΈ
3:56
3:56
Play later
Play later
Lists
Like
Liked
3:56Thrilled to see a major step forward in dengue prevention! π¦π A new NEJM study reports that daily mosnodenvir, a first-in-class antiviral targeting the NS3βNS4B interaction, significantly reduced DENV-3 viral load and prevented infection in a controlled human challenge model. π𧬠It's early, but the results offer real hope for a long-awaited oral deβ¦
…
continue reading
1
Storms, Syncope, Survival π©οΈπ΅βπ«β€οΈ β Long QT Syndrome update
4:46
4:46
Play later
Play later
Lists
Like
Liked
4:46Delighted to share a concise update on the latest NEJM review of Long QT Syndrome π«π β a masterful synthesis by Schwartz & Crotti that reframes how we recognize risk, personalize therapy, and prevent sudden death in this genetically mediated disorder. The piece highlights ion-channel biology, gene-specific triggers, the impact of modifier genes, anβ¦
…
continue reading
1
Dr RR Baliga's Philosophical Discourses: Gottfried Wilhelm Leibniz (Germany, 1646β1716 CE) β Monadology
3:15
3:15
Play later
Play later
Lists
Like
Liked
3:15π§ β¨ Leibniz: Harmony, Logic, and the Birth of the Digital Mind Celebrating Gottfried Wilhelm Leibniz β the mathematician-philosopher who co-created calculus, invented binary arithmetic, and envisioned a world stitched together by pre-established harmony. His Monadology reads like proto-systems theory, and his binary system is the quiet ancestor of eβ¦
…
continue reading
1
Genes, Environment, Development π§¬πΏπ§ β A 2025 Perspective on Autism
5:15
5:15
Play later
Play later
Lists
Like
Liked
5:15𧬠New insights into autism: A 2025 JCI Viewpoint highlights how hundreds of genes, polygenic risk, and specific environmental factors converge during fetal brain development to shape autism likelihood. π§ Early biomarkersβfrom infant MRI and ERPs to machine-learning models using EHR dataβare accelerating earlier, more tailored interventions. π± Advanβ¦
…
continue reading
1
Numbness β’ Nerves β’ Nuance π¦Άβ‘π§ β Decoding Peripheral Neuropathy
4:58
4:58
Play later
Play later
Lists
Like
Liked
4:58π Peripheral Neuropathy: What Clinicians Should Know π§ β‘ Peripheral neuropathy affects ~1% of adults worldwide, with diabetes accounting for more than half of all cases. The JAMA review highlights why length-dependent patterns dominate, how metabolic stress injures long axons first, and why sensory symptoms outpace motor loss. Evidence-based evaluatβ¦
…
continue reading
1
Stroke Risk, Stent Benefit, Surgical Uncertainty π§ β¨π§
5:12
5:12
Play later
Play later
Lists
Like
Liked
5:12New NEJM insights on asymptomatic carotid stenosis π§ π The CREST-2 trials offer a landmark update: intensive medical therapy remains the cornerstone, while carotid stenting shows selective benefit when performed by expert operators. Endarterectomy, however, provides no significant advantage over modern medical management. With stricter blood-pressurβ¦
…
continue reading
1
UPFs, Diets, Disease: The Global Drift πβ‘οΈπβ‘οΈβ οΈ
6:26
6:26
Play later
Play later
Lists
Like
Liked
6:26The new Lancet Series on ultra-processed foods offers a striking insight: as UPFs rise globally, traditional whole-food diets declineβbringing nutrient imbalance, overeating, toxic exposures, and hyper-palatable formulations that quietly reshape health trajectories. πβ‘οΈβ οΈ Across more than 100 prospective studies and multiple trials, higher UPF intaβ¦
…
continue reading
1
Toby Maher, MD, MSc, PhD - Clearing the Air on Fibrosing ILDs: Pulmonologist Conversations on Timely Diagnosis and Modern Care With Antifibrotic Therapy
56:46
56:46
Play later
Play later
Lists
Like
Liked
56:46This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/UEK865. CME/AAPA cβ¦
…
continue reading
1
Professor Julian Gillmore / Mathew S. Maurer, MD - Exploring New Paradigms in Transthyretin Cardiac Amyloidosis Care: Experts vs AI
54:26
54:26
Play later
Play later
Lists
Like
Liked
54:26This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/NCPD/CPE/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/UBF8β¦
…
continue reading
1
Groceries, Guidance, Gains πππ β How DASH Delivery Lowers Blood Pressure
4:50
4:50
Play later
Play later
Lists
Like
Liked
4:50Home-delivered DASH-patterned groceries paired with dietitian counseling meaningfully lowered blood pressure and LDL cholesterol among Black adults living in food deserts π₯πβas demonstrated in the GoFresh randomized trial (JAMA). An accompanying editorial highlights why future "food-as-medicine" programs must prioritize underconsumed, health-promotβ¦
…
continue reading
1
Hemodialysis, Cardiovascular Burden, Therapeutic Hope π©Ίβ€οΈπ β Can Omega-3 Fatty Acids Bend the Risk Trajectory?
4:57
4:57
Play later
Play later
Lists
Like
Liked
4:57π©Ί New insights in hemodialysis care. A major New England Journal of Medicine study reports that daily supplementation with long-chain omega-3 fatty acids (eicosapentaenoic acid and docosahexaenoic acid) led to a 43% reduction in serious cardiovascular events among adults receiving maintenance hemodialysis. ππ In a population where traditional cardiβ¦
…
continue reading
1
π Oral, Potent, Proven β Enlicitide Redefines LDL Control
7:03
7:03
Play later
Play later
Lists
Like
Liked
7:03π A milestone moment in lipid therapeutics! The new JAMA trial on the oral PCSK9 inhibitor Enlicitide reports a ~60% reduction in LDL-C, with parallel decreases in ApoB and Lp(a)βall on top of maximally tolerated statin therapy. For individuals with heterozygous familial hypercholesterolemia (HeFH)βwhere reaching LDL targets remains a persistent chβ¦
…
continue reading
1
One Cup of Coffee. Less Atrial Fib/Flutter. More Life βπβ‘οΈπ
3:07
3:07
Play later
Play later
Lists
Like
Liked
3:07β DECAF Trial insight! A new JAMA study shows that daily caffeinated coffee may lower recurrence of atrial fibrillation compared with abstinence. Patients drinking ~1 cup/day had 47% recurrence vs 64% with abstinence (HR 0.61, p=0.01) ππ No major safety concernsβchallenging long-held beliefs that coffee is proarrhythmic. π‘Takeaway: For many patientβ¦
…
continue reading
Dr. Chino talks with Dr. Navneet Majhail and patient advocate Laurie Adami about CAR-T therapy, an advance cancer treatment that biologically engineers a patient's own T-cells to recognize and kill cancer cells. This discussion will be based off the JCO OP article, "Outpatient Administration of Chimeric Antigen Receptor T-Cell Therapy Using Remote β¦
…
continue reading
1
Beyond the Culprit: Complete Revascularisation β’ Fewer Deaths β’ Better Futures ππ©Ίβ¨
4:42
4:42
Play later
Play later
Lists
Like
Liked
4:42π¨ New insights from The Lancet π¨ A major individual-patient-data meta-analysis (6 RCTs, 8,836 patients) shows that complete revascularisation in acute myocardial infarction significantly reduces cardiovascular death, all-cause mortality, and recurrent MI. ππ Benefits were consistent across age, sex, STEMI/NSTEMI, and lesion characteristics β strengβ¦
…
continue reading
1
Olezarsen Cuts Triglycerides. Calms Pancreas. Changes Outcomes. π§¬π₯π‘οΈ
2:31
2:31
Play later
Play later
Lists
Like
Liked
2:31𧬠New NEJM data on Olezarsen! In patients with severe hypertriglyceridemia, monthly RNA-targeted therapy delivered major triglyceride reductions (β62% to β72%) and a significant drop in acute pancreatitis risk (rate ratio 0.15). β¨ Improvements extended to ApoC-III, remnant cholesterol, and non-HDL cholesterol, with consistent benefits across both Cβ¦
…
continue reading
1
MI Aftercare: The Beat Goes OnβWith or Without Beta-Blockers π₯β‘οΈβ€οΈ
3:16
3:16
Play later
Play later
Lists
Like
Liked
3:16π New Evidence from NEJM In a large meta-analysis of 17,801 patients with preserved LVEF after MI, beta-blockers did not reduce death, recurrent MI, or heart failure. Event rates were low, and outcomes were similar with or without therapy. π«π This clarifies practice for a growing post-MI population with LVEF β₯50%βprecision matters more than traditiβ¦
…
continue reading
1
Malaz Boustani, MD, MPH, Charles Vega, MD, FAAFP - Brain Health Morning Report: Adapting Primary Care Practice and Workflows to Meet the Needs of an Aging Population
1:01:46
1:01:46
Play later
Play later
Lists
Like
Liked
1:01:46This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/MOC/NCPD/CPE/AAPA/APA/IPCE information, and to apply for credit, please visit us at PeerView.β¦
…
continue reading
1
Jiwon Oh, MD, PhD, FRCPC - Quiet Progression, Loud Impact in MS: Expert Insights on the Role of BTK Inhibitors Beyond Relapse
34:15
34:15
Play later
Play later
Lists
Like
Liked
34:15This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/AAPA information, and to apply for credit, please visit us at PeerView.com/CXV865. CME/AAPA cβ¦
…
continue reading
1
Prof. Dr. med. Alexander Drzezga - Nuclear Medicine for Alzheimerβs Disease in the Hot Seat: Case Conference on Advancing Early Diagnosis With PET Imaging and Biomarkers
1:09:59
1:09:59
Play later
Play later
Lists
Like
Liked
1:09:59This content has been developed for healthcare professionals only. Patients who seek health information should consult with their physician or relevant patient advocacy groups. For the full presentation, downloadable Practice Aids, slides, and complete CME/EBAC/AAPA/IPCE information, and to apply for credit, please visit us at PeerView.com/APF865. β¦
…
continue reading
1
NOAC Monotherapy Wins in Afib with Drug Eluting Stents: Safer, Stronger, Smarter βοΈπ₯π§
3:02
3:02
Play later
Play later
Lists
Like
Liked
3:02π’ ADAPT AF-DES Trial β A Safer Path Forward! In patients with atrial fibrillation beyond 1 year after drug-eluting stent implantation, NOAC monotherapy delivered striking benefits over combination therapy. β
Lower net adverse clinical events β
Marked reduction in major/CRNM bleeding β
Similar ischemic protection A beautifully simple strategy with mβ¦
…
continue reading
1
OCEAN Trial: Ablate Afib. Assess. Anticoagulate? π
3:53
3:53
Play later
Play later
Lists
Like
Liked
3:53π OCEAN Trial offers fresh insight into antithrombotic therapy after successful AF ablation. In 1284 patients followed for 3 years, event rates were remarkably low π. Rivaroxaban did not show superiority over aspirin for preventing stroke, systemic embolism, or covert embolic events, while bleeding risk was higher with anticoagulation. π§ 96% had noβ¦
…
continue reading
1
Dr RR Baliga's Philosophical Discourses: John Locke (England, 1632β1704 CE) β Empiricism
5:27
5:27
Play later
Play later
Lists
Like
Liked
5:27π§ John Locke: Experience β’ Liberty β’ Toleration Born a physician-philosopher, Locke championed empiricism β the idea that knowledge begins with experience, not dogma. His tabula rasa shaped modern psychology, while his Two Treatises of Government defined rights, consent, and freedom that echo through modern democracies. For clinicians, his legacy rβ¦
…
continue reading
1
Evolocumab in Primary Prevention." π§¬π‘οΈπ― LDL: Down 55%. CV Events: Down 25%.
4:52
4:52
Play later
Play later
Lists
Like
Liked
4:52π VESALIUS-CV delivers powerful evidence: in high-risk patients without prior MI or stroke, evolocumab significantly reduced 3-point MACE by 25% and 4-point MACE by 19%, with LDL-C lowered to a median of 45 mg/dL. π‘ These results expand the horizon of prevention, showing that deep LDL reduction is both safe and effective in averting first cardiovasβ¦
…
continue reading
1
Capillary Clues, Clinical Wins: Targeting Capillary Refill Time in Acute Septic Shock ππ©Έβ
4:48
4:48
Play later
Play later
Lists
Like
Liked
4:48π« Septic Shock, Refined at the Fingertips β±οΈ A powerful new JAMA (2025) trial brings us one step closer to truly personalized resuscitation. The ANDROMEDA-SHOCK-2 study shows that targeting capillary refill time (CRT) β a simple bedside sign β can shorten time on organ support vs usual care, without increasing mortality. Key insight: Sometimes the β¦
…
continue reading
1
SOFA-2 ICU Unveiled π§ βοΈπ 3 Million Patients, 9 Nations, One New Standard
4:38
4:38
Play later
Play later
Lists
Like
Liked
4:38π¨ SOFA-2 arrives β a thoughtful evolution in critical care scoring π§ π«π« After nearly 30 years, the SOFA score has been modernized using data from >3.3 million ICU patients across 9 countries. The updated SOFA-2 incorporates contemporary respiratory and cardiovascular supports (HFNC, NIPPV, vasopressors, ECMO) and refines thresholds while preserving β¦
…
continue reading
1
SOFA-2 Unveiled π§ βοΈπ-ππ©Ίπ¨ β Critical Care Enters a New Era
4:15
4:15
Play later
Play later
Lists
Like
Liked
4:15SOFA-2 is here β a major advance in assessing organ dysfunction in critical illness π§ π«β€οΈ Three decades after the original SOFA score, this updated framework reflects modern ICU practice β integrating contemporary organ support (ventilation, vasopressors, RRT), delirium recognition, and global feasibility across resource settings ππ Validated in 3.3β¦
…
continue reading
1
π Peripartum Cardiomyopathy: Detect Early β’ Treat Aggressively β’ Protect Mothers
5:01
5:01
Play later
Play later
Lists
Like
Liked
5:01π Peripartum Cardiomyopathy: When a Mother's Heart Fights for Two Peripartum cardiomyopathy is a leading yet often missed cause of maternal morbidity and mortalityβstriking late in pregnancy or months postpartum. Early suspicion, timely echo, and guideline-directed therapy save lives. π©Ί π§ Bromocriptine, careful anticoagulation, and multidisciplinarβ¦
…
continue reading
1
Rethinking "default arterial lines" in the ICU π§ π
5:00
5:00
Play later
Play later
Lists
Like
Liked
5:00Rethinking "default lines" in the ICU π§ π A landmark NEJM trial shows that in patients with shock, deferring arterial catheterization and using automated cuff monitoring was noninferior for 28-day mortality β and reduced catheter-related complications. A gentle reminder: not every sick patient needs a needle to be well cared for. Precision isn't onlβ¦
…
continue reading
1
Light Pollution, Circadian Disruption, Cardiac Vulnerability ππ°οΈπ«
4:19
4:19
Play later
Play later
Lists
Like
Liked
4:19π Bright Nights, Higher Heart Risk β€οΈβπ©Ή New findings in JAMA Network Open highlight that greater exposure to artificial light at night is associated with significantly increased risks of coronary artery disease, myocardial infarction, heart failure, atrial fibrillation, and stroke β independent of sleep duration, lifestyle factors, and genetics. π‘ β¦
…
continue reading
1
Rethinking Immune Aging: It Starts Sooner Than We Think π‘π©Έ
4:23
4:23
Play later
Play later
Lists
Like
Liked
4:23The immune clock starts earlier than we think β³π§¬ A landmark Nature study shows that immune aging begins quietly in midlife β decades before clinical frailty. Using >16M single-cell profiles and longitudinal vaccine responses, researchers found: β’ Stable, early transcriptional drift in naΓ―ve & memory T cells β’ A subtle TH2 shift that may weaken antiβ¦
…
continue reading
1
Seven Years Later: TAVR Didn't Blink ππ«
3:28
3:28
Play later
Play later
Lists
Like
Liked
3:28π« TAVR or SAVR? The 7-Year Truth New 7-year results from the PARTNER-3 trial (NEJM) show that in low-risk patients with severe symptomatic aortic stenosis, TAVR holds pace with surgery β delivering comparable survival, stroke rates, rehospitalization, valve durability, and quality-of-life outcomes. π Highlights β’ Composite events: 34.6% (TAVR) vs 3β¦
…
continue reading
1
Dr RR Baliga's Philosophical Discourses: Baruch Spinoza (Netherlands, 1632β1677 CE) β Ethics
6:00
6:00
Play later
Play later
Lists
Like
Liked
6:00πΏ Spinoza: Reason, Nature, Freedom Today's deck explores Baruch Spinoza β the quietly revolutionary Dutch philosopher who shaped rationalism, modern biblical criticism, and secular democracy. He saw God = Nature, championed intellectual freedom, and argued that understanding our emotions transforms them β not far from cognitive-behavioral ideas we β¦
…
continue reading
1
New Mitral Frontier πͺπ«πΆββοΈ TMVR Opens a Third Pathway
5:14
5:14
Play later
Play later
Lists
Like
Liked
5:14A new era for complex mitral regurgitation. The ENCIRCLE pivotal trial in The Lancet reports that fully percutaneous, transfemoral, transseptal TMVR (SAPIEN M3) achieved durable MR reduction (β96% β€1+ at 1 year), low early mortality, and meaningful improvement in symptoms and quality of life for patients unsuitable for surgery or TEER. A third pathβ¦
…
continue reading
1
Immune Fountain of Youth? Mesenchymal Magic π§β¨
3:44
3:44
Play later
Play later
Lists
Like
Liked
3:44𧬠Can we rejuvenate the aging immune system? A remarkable Nature Biotechnology study shows that a rare population of periostin-positive mesenchymal niche cells can rebuild the adult thymus, recruit new T-cell progenitors, and restore immune responses after injury. By harnessing CCL19-expressing stromal support, the authors demonstrate a path towardβ¦
…
continue reading
1
Cancer, Cure, Cardio-Care π¬β
π« Not Every Survivor Needs a Cardiologist β But Every Heart Needs Attention
4:53
4:53
Play later
Play later
Lists
Like
Liked
4:53π©ΊποΈ Cardio-Oncology Insight: Not Every Breast Cancer Survivor Needs a Cardiologist As breast cancer survivorship grows, understanding who truly benefits from long-term cardiac follow-up becomes essential. An important editorial in JAMA Oncology underscores a key principle: risk-stratified care, not reflex surveillance. π©ββοΈπ Age and traditional carβ¦
…
continue reading
1
Urolithin A: The Immune Youth Serum? β¨π§«π§β‘οΈπ§ββοΈ
3:41
3:41
Play later
Play later
Lists
Like
Liked
3:41𧬠Can we rejuvenate the aging immune system? A new Nature Aging trial suggests we might be closer than we thought. In 50 healthy adults aged 45β70, urolithin Aβa mitophagy activatorβimproved immune fitness over just 28 days: β
β naΓ―ve CD8βΊ T cells β
β exhaustion markers (TOX) β
β mitochondrial biogenesis (PGC-1Ξ±) β
β fatty-acid oxidation capacity β
β¦
…
continue reading
1
Short DAPT Wins, Ultra-Short Fails π«1οΈβ£β
3οΈβ£ Stratified Strategy From HOST-BR
3:49
3:49
Play later
Play later
Lists
Like
Liked
3:49π« Personalizing DAPT: When "One Size Fits All" Fails ποΈπ The HOST-BR trial in The Lancet offers an important clinical lesson: Bleeding risk should guide antiplatelet duration after PCI β not habit, not inertia. π Key insight In ARC-HBR patients, 1-month DAPT was not non-inferior to 3 months In non-HBR patients, 3-month DAPT was non-inferior to 12 mβ¦
…
continue reading