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Help me fill in the blanks of the practice of ED Critical Care. In this podcast, we discuss all things related to the crashing, critically ill patient in the Emergency Department. Find the show notes at emcrit.org.
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🧬⏳ New Insights into Organ-Specific Aging! 🧠❤️🩺
Just explored a remarkable Nature Aging study showing how organ-specific proteomic clocks can forecast disease, cognitive decline, and even longevity with impressive precision. These clocks—built from >2,900 plasma proteins—reveal that the brain, kidney, and arteries age on their own timelines, each carrying unique clues about future health.
What struck me most is how brain aging outperforms traditional risk markers, predicting dementia even after accounting for age, APOE genotype, and cognitive scores. A powerful reminder that biological age isn't a single number—it's a symphony of organ-specific rhythms. 🎼
Exciting implications for precision medicine, early detection, and preventive cardiometabolic and neurodegenerative care.
Science that helps us see aging not as fate, but as a map. 🗺️✨
799 episodes
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