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EP Edge Journal Watch

Niraj Sharma MD FACC FHRS

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Welcome to EP Edge Journal Watch — where cardiac electrophysiology meets evidence, precision, and perspective. Hosted by Dr. Niraj Sharma, this bi-weekly podcast distills high-impact cardiovascular and EP research into clear, clinically meaningful insights. Each episode goes beyond headlines and abstracts to uncover what new studies actually mean for patient care, decision-making, and the future of electrophysiology. What EP Edge Journal Watch stands for: Evidence-based practice Precision el ...
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The Onco Life Podcast

DR. CHRISTINA NG VAN TZE

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Welcome to The Onco Life Podcast, your trusted source for cancer care insights, treatment updates, and patient-centered education. Hosted by the team at Onco Life Centre in Kuala Lumpur, Malaysia, this podcast is designed to guide patients, caregivers, and listeners through every stage of the cancer journey. Each episode features expert advice from our oncologists, wellness tips, treatment innovations, and answers to the most common questions about cancer types, therapies, and recovery. 🎧 Em ...
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Doctor Thyroid

Philip James interviews top thyroid experts about surgery, nutrition, endoc

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This show is for thyroid patients determined to improve their quality of life, with the best information available. You will gain insight from those who have discovered improved well-being regardless of setbacks, and hear from leading healthcare professionals, including endocrinologists, surgeons, functional medicine practitioners, and radiologists.
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This episode explains how radiofrequency ablation, or RFA, is used as a minimally invasive treatment for liver tumors. You will learn how the procedure works, who it helps, and what results patients can expect. Listeners will learn: • How radiofrequency ablation destroys liver tumors using heat • When RFA is recommended for liver cancer and liver m…
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This episode breaks down a groundbreaking 2025 study that reveals how quitting smoking within six months of a cancer diagnosis can add nearly one extra year of life. You will learn why smoking cessation is now considered an essential part of modern cancer care. Quitting smoking reduces the risk of death by 30 to 50 per cent Why the survival benefit…
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This episode explores how immunotherapy is transforming cervical cancer treatment, especially for women with advanced or recurrent disease. You will learn how this targeted approach strengthens the immune system and offers new hope when traditional treatments fall short. Listeners will learn: • What immunotherapy is and how it helps the immune syst…
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This episode explains the main surgical treatments for cervical cancer, how each procedure works, and when surgery is recommended. You will learn the differences between early-stage and advanced surgical options, along with the benefits and possible side effects. Listeners will learn: • The most common surgeries for cervical cancer include cone bio…
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This episode breaks down how radiation therapy treats cervical cancer, the types of radiation used, and when this treatment is recommended. You will learn how radiation targets cancer cells, improves treatment outcomes, and supports patients at different stages of cervical cancer. Listeners will learn: • How radiation therapy destroys cervical canc…
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This episode explains how chemotherapy works for cervical cancer, when it is used, and what patients and caregivers can expect during treatment. You will learn how chemotherapy helps treat locally advanced, recurrent, and metastatic cervical cancer while improving outcomes and quality of life. Listeners will learn: • What chemotherapy for cervical …
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This episode breaks down the key differences between squamous cell carcinoma and non keratinizing nasopharyngeal cancer, helping listeners understand how each type develops, how EBV is involved, and what treatment options are most effective. Listeners will learn: • The core differences between squamous cell carcinoma and non-keratinizing NPC • Why …
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This episode explains how oncologists help patients manage common chemotherapy side effects, from nausea and fatigue to hair loss and neuropathy. You will learn how oncology care teams support both physical and emotional well-being throughout treatment. Listeners will learn: • How cooling therapy and wig options help reduce the impact of hair loss …
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Smartwatches are now among the most widely used heart-monitoring tools in the world — but how accurate are they really at detecting AFib? In this December 2025 Issue 3 of EP-Edge Journal Watch, Dr. Niraj Sharma, cardiologist and cardiac electrophysiologist, breaks down the strongest evidence to date on smartwatch AFib detection, Apple Watch ECG per…
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This episode explains what it means to live with stage 4 breast cancer, how the disease spreads, and the modern treatments that help patients manage symptoms and maintain quality of life. Listeners will learn: • What metastatic breast cancer is and how it spreads • Key treatments like chemotherapy, targeted therapy, hormone therapy, and immunothera…
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In this episode, host Dr. Kristine Smith speaks with Mr. James Bates. They discuss the recently published Original Article: “A Phase 1 Research Trial to Evaluate the Safety and Effectiveness of Intranasal Botulinum Toxin Type A Spray for Patients With Rhinitis.” The full manuscript is available in the International Forum of Allergy and Rhinology. L…
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This episode breaks down the key differences between primary and secondary liver cancer so listeners can better understand how each type develops and is treated. You will learn how these cancers start, how they spread, and which treatment options are most effective. Listeners will learn: What primary liver cancer is and how it develops in liver cel…
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This episode explains the major differences between MRI and CT scans in diagnosing and managing nasopharyngeal carcinoma, and when each imaging test is most useful. You will learn how these scans work, what they show, and why doctors choose one over the other. What MRI reveals about soft tissues and early tumor changes Why MRI is preferred for mapp…
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This episode explains the key treatment options for stage 4 colorectal cancer and how patients can manage side effects to maintain a better quality of life. You will learn how modern therapies, nutrition, emotional support, and clinical trials can help patients live longer and feel better. In this episode, you will learn: How chemotherapy, radiatio…
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Cancer treatment often changes how patients experience food, turning meals into a source of stress instead of comfort. In this episode, we explore how programs like the Garden of Hope are helping cancer patients rebuild a positive relationship with eating through gardening, cooking, and community support. Listeners will learn: How chemotherapy and …
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Finding the right oncologist is one of the most important steps in your cancer journey. The right specialist can make all the difference in treatment success, comfort, and long-term outcomes. In this episode, we discuss how to choose the best oncologist for your type of cancer and what factors truly matter. You’ll learn: The main types of oncologis…
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This episode explores when and why a CT scan is crucial for diagnosing nasopharyngeal cancer. Learn how CT, MRI, and PET CT scans work together to detect tumors early, guide treatment planning, and improve patient outcomes. Listeners will learn: How CT scans reveal tumor size, shape, and spread in nasopharyngeal cancer The difference between CT, MR…
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In this special EP Edge Journal Watch episode, Dr. Niraj Sharma delivers a critical analysis of the landmark AQUATIC Trial, published in the New England Journal of Medicine (October 2025). This pivotal study explores optimal antithrombotic strategies in patients with atrial fibrillation (AF) and coronary artery disease (CAD) — balancing ischemic pr…
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If your doctor has recommended a head and neck CT scan to check for nasopharyngeal cancer (NPC), knowing what to expect can make the process less stressful. This episode walks you through every stage of the diagnostic experience so you can feel informed and confident. In this episode, you’ll learn: Why CT scans are vital for detecting nasopharyngea…
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This episode explores how genetic factors influence prostate cancer risk among Malaysian men and why understanding these risks is key to early detection and better outcomes. Listeners will learn: How family history increases prostate cancer risk The role of inherited gene mutations such as BRCA1, BRCA2, and HOXB13 Why ethnic-specific genetic variat…
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Liver cancer often develops quietly, but recognizing its early warning signs can make all the difference. In this episode, we discuss the key symptoms to watch for and how early detection can lead to better treatment outcomes. Listeners will learn: The most common early signs of liver cancer include fatigue and weight loss Why changes in appetite a…
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Trust is the foundation of effective cancer care. In this episode, we explore how building a strong patient-oncologist relationship improves communication, treatment adherence, and overall patient outcomes. Listeners will learn: Why trust is essential for patient-centered cancer care How oncologists build trust through empathy, honesty, and clear g…
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In this episode, Dr. Niraj Sharma breaks down six pivotal studies shaping today’s electrophysiology and cardiology practice—from lifestyle-driven AF control (ARREST-AF) and post-CABG atrial fibrillation management to the DOAC + aspirin conundrum in stable CAD, the return of digitoxin in HFrEF, insights from CABANA-Substudy, and the latest ICD regis…
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In this inaugural episode, Dr. Niraj Sharma breaks down three pivotal studies that could shift daily EP practice: How high-normal potassium targeting can reduce VT burden (POT-CAST trial). When GDMT withdrawal may be safe after recovery from tachycardia-induced cardiomyopathy. Why adverse pregnancy outcomes may predict long-term AF risk. Get the si…
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Discover how Onco Life Centre helps patients with Stage IV nasopharyngeal cancer through advanced, personalized care. Our consultant oncologists use the latest targeted therapy, immunotherapy, and radiation treatments to control cancer growth while focusing on comfort, strength, and quality of life. In this episode, you’ll learn: What Stage IV naso…
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Learn how Onco Life Centre provides clear, compassionate care for patients with Stage III nasopharyngeal cancer. Our expert oncologists design detailed, personalized plans to control cancer growth, protect health, and support long-term recovery through every phase of treatment. In this episode, you’ll learn: What Stage III nasopharyngeal cancer mea…
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Learn how Stage II nasopharyngeal cancer is diagnosed and treated with precision at Onco Life Centre. Our expert oncologists design personalized treatment plans that combine advanced therapies with continuous care to stop cancer early and protect quality of life. In this episode, you’ll learn: What Stage II nasopharyngeal cancer means and why early…
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Early signs of prostate cancer can be subtle, but knowing what to watch for can make all the difference. In this episode, we explore the key symptoms, testing methods, and lifestyle habits that help men catch prostate cancer before it advances. Listeners will learn: Common early signs of prostate cancer, such as urinary changes and lower back pain …
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Liver cancer is one of the most common and serious cancers worldwide, often developing in those with chronic liver disease, obesity, or hepatitis infections. In this episode, we break down the types of liver cancer, its early warning signs, and the major risk factors to watch for. You’ll learn: What liver cancer is and how it develops The main type…
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Learn how early diagnosis of Stage I nasopharyngeal cancer leads to higher success rates and faster recovery. At Onco Life Centre, our specialists use advanced imaging and personalized treatment plans to target cancer effectively while protecting healthy tissues. In this episode, you’ll learn: What defines Stage I nasopharyngeal cancer, and why ear…
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Discover how Onco Life Centre supports patients who need surgery for nasopharyngeal cancer through expert coordination, preparation, and recovery care. While surgery is performed at partner hospitals, our oncologists ensure every patient receives safe, seamless, and fully guided treatment. In this episode, you’ll learn: When surgery is recommended …
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This episode breaks down why lung cancer screening is crucial, who should get tested, and how early detection can make all the difference. Learn how LDCT scans help spot lung cancer early, the benefits of screening, and what risks to be aware of before you get tested. In this episode, you’ll learn: Who qualifies for lung cancer screening based on a…
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Explore how combined targeted therapy helps treat nasopharyngeal cancer with precision and care. At Onco Life Centre, doctors use advanced methods to target cancer growth, improve survival rates, and minimize side effects through fully personalized treatment plans. In this episode, you’ll learn: What makes targeted therapy different from traditiona…
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Learn how chemotherapy helps treat nasopharyngeal cancer by targeting cancer cells throughout the body, reducing tumor size, and improving survival rates. At Onco Life Centre, personalized care plans are designed to balance effectiveness with patient comfort and well-being. In this episode, you’ll learn: What chemotherapy for nasopharyngeal cancer …
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In this episode, we break down everything you need to know about prostate cancer, one of the most common cancers affecting men worldwide. Learn how to recognize early warning signs, understand your risk factors, and take proactive steps for early detection and treatment. Listeners will learn: What prostate cancer is and how it develops Common sympt…
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Discover how advanced radiation therapy helps treat nasopharyngeal cancer safely and effectively. At Onco Life Centre, each treatment plan is personalized to target cancer cells precisely while protecting healthy tissues for the best possible outcomes. In this episode, you’ll learn: What is nasopharyngeal carcinoma (NPC) and how does it develop Com…
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When liver cancer progresses to advanced stages, treatment shifts from curative options to focusing on comfort, quality of life, and slowing disease progression. Understanding stage 3 and stage 4 liver cancer helps patients and families prepare for what lies ahead and explore supportive care options. In this episode, you’ll learn: How liver cancer …
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This episode explores how real-world evidence (RWE) is transforming prostate cancer treatment and clinical decision-making. You’ll learn how RWE complements randomized controlled trials (RCTs) and offers deeper insight into long-term outcomes, treatment adherence, and diverse patient populations. In this episode, you’ll learn: Why RWE is becoming e…
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Your liver plays a vital role in maintaining overall health and supporting cancer care. In this episode, discover how the liver functions, what tests can detect problems early, and how to keep it healthy during cancer treatment. Listeners will learn: How the liver processes nutrients, removes toxins, and supports digestion The difference between pr…
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A new FDA-approved combination of lurbinectedin and atezolizumab is changing the outlook for patients with extensive-stage small cell lung cancer (ES-SCLC). This first-line maintenance therapy offers a major step forward in extending survival and disease control after initial treatment. In this episode, you’ll learn: • How the lurbinectedin + atezo…
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The intermediate stage of liver cancer, often called stage 2, is a turning point where tumors are larger or involve blood vessels but have not spread widely. At this stage, doctors balance treatment with preserving liver function, making it crucial for patients to understand their options. In this episode, you’ll learn: How doctors use the BCLC sys…
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Early-stage liver cancer treatment gives patients the strongest chance for long-term survival since tumors are small, localized, and the liver is still functioning well. At stage 1, surgery, liver resection, or transplant may offer curative results, while local therapies provide effective alternatives when surgery isn’t possible. In this episode, y…
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In this episode, host Dr. Douglas Reh speaks with Dr. Masayoshi Takashima. They discuss the recently published Original Article: “3-Year Outcomes of Temperature-Controlled Radiofrequency Ablation of the Posterior Nasal Nerve in Patients With Chronic Rhinitis.” The full manuscript is available as open access in the International Forum of Allergy and…
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Your first visit with an oncologist can feel overwhelming, but understanding what happens during the appointment can help you feel more confident and prepared. In this episode, we explain exactly what to expect at your initial oncology consultation and how it lays the foundation for your personalized cancer care plan. In this episode, you’ll learn:…
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Immunotherapy is transforming the way doctors treat liver cancer, especially advanced hepatocellular carcinoma (HCC). By training the body’s immune system to recognize and attack cancer cells, immunotherapy provides hope for patients who cannot undergo surgery or whose cancer no longer responds to other treatments. In this episode, you’ll learn: Ho…
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Targeted therapy is changing how doctors treat liver cancer, especially in advanced stages where surgery isn’t possible. By blocking the specific growth signals that fuel tumors, these treatments slow cancer progression, cut off blood supply to tumors, and support the immune system, all with fewer side effects than chemotherapy. In this episode, yo…
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