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Welcome to “A Dose of Reality”, the podcast where we infuse insight, laughter, and practical wisdom into the world of clinical leadership and career development. Hosted by Charles Spence, each episode offers a deep dive into the challenges and triumphs of clinical leadership, providing listeners with meaningful conversations, career insights, and a dose of inspiration to navigate their professional journeys. Whether you're a director, a C-level executive, or a clinical researcher in oncology ...
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Adventures in Angular

Charles M Wood

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Join our weekly discussion about how to build top end Angular applications and become an Angular expert. Become a supporter of this podcast: https://www.spreaker.com/podcast/adventures-in-angular--6102018/support.
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The Better Different | We Kill Mediocrity

Thebetterdifferent.com - Dennis van der Locht

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Join our mission to kill mediocre marketing and lame branding! We the entrepreneurial spirits, marketing executives, CEO’s and start-up hipsters make our way into the lives of millions of people. With the great brands we create, we have the great responsibility to not be lame. The Better Different puts a stop to boring brands and their annoying marketing tricks and interruptive advertising. We share the stories of the brightest and delighted to inspire each other to create better brands and ...
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The Curiosity Project is a podcast where curiosity DIDN'T kill the cat. Whether you want to listen to a serious discussion on artificial intelligence, sustainability of books, philosophy of movies, the beauty of minimalism or a laid back comedic chat on the British royal family then Omar and Umar have you covered. Exploration and discovery is at the heart of this podcast so be curious and join us for a chat!
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Where there’s more than meets the eye. What if your senses were the secret to creating unforgettable stories? Uncover the magic and science behind what makes us feel, starting at first sight. From the colour of sound to shapes that taste sweet. I’ll take you behind the scenes with perfumers, scientists, writers, chefs, artists, musicians, makers, designers and athletes, to reveal how they connect what we see to what we sense. Because the real alchemy happens when we talk to people across dif ...
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Minute Women

Minute Women

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Minute Women is your weekly dose of Canadian history and corny 90s nostalgia. We are best friends Grace McNutt and Linnea Swinimer and we are on a mission to tell the untold stories behind the iconic Canadian Heritage Minutes. Along the way, we uncover the funny, weird, and downright terrifying stories left out of Canada’s national history. Did you know John A. Macdonald's younger brother was murdered in a freak gin incident? Or that Sandford Fleming was going to call standard time "cosmic t ...
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In this episode, I talked with Johan Baeck, Executive Vice President and Chief Medical Officer at Promontory Therapeutics, a clinical-stage biotech focused on developing novel small molecule immunogenic anti-cancer therapies. Johan shares insights from a career spanning large pharma (Novartis, Abbott) and biotech startups, with contributions to the…
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How sight changes flavour, and why the brain believes what it sees. “None of us believe that our senses affect us as much as, in fact, the evidence shows that they do.” Can changing a drink’s colour change its flavour? Professor Charles Spence reveals how visual cues shape what we taste, and how even wine experts can be fooled by their eyes. From p…
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What can you learn by going behind the scenes in an experimental psychology lab, a perfume maker’s studio, a stand-up comedy show or an immersive chef’s table supper club? This is the countdown to the launch of a brand new podcast Seeing Senses with Sarah Hyndman Where there’s more than meets the eye Launching on Thursday 22nd May Subscribe to the …
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In this episode, I talked with Peter Tummino, President of Research and Development at Nimbus Therapeutics, where he discussed what it takes to build a successful biotech R&D engine. Peter shares his insights on company culture and its impact on drug discovery, the challenges of targeting difficult-to-drug proteins, and the lessons he’s learned fro…
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In this episode, I talked with Abigail (Abbey) Jenkins, a pharmaceutical executive with 25+ years of experience, who shares her career journey, highlighting her entry into the industry, proud achievements, and the challenges she faced along the way. She emphasizes the importance of resilience, community, and learning from both successes and failure…
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Joseph (Joe) Birkett, Executive Director of Medical Affairs at Aura Biosciences, joined our podcast to share what he’s learned over two decades in oncology drug development, including the career-defining moments and the painful missteps that shaped his approach. Joe speaks openly about his proudest contribution—helping lead Obinutuzumab to regulato…
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In this episode, I talked with Dr. Bruce Dezube, Senior Vice President, Clinical Development of Xilio Therapeutics, a clinical-stage biotechnology company focused on developing tumor-activated immuno-oncology therapies. Here he shares his extensive career in oncology and drug development, discussing his journey from academia to industry, the challe…
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Seeing Senses podcast Where there’s more than meets the eye What if your senses were the secret to creating unforgettable stories? I’m Sarah Hyndman, and this is Seeing Senses — a podcast that uncovers the magic and science behind what makes us feel, starting at first sight. From the colour of sound to shapes that taste sweet. I’ll take you behind …
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Connecting the Senses: In this episode, we chat with Charles Spence, head of Oxford's Crossmodal Research Lab, about the fascinating world of crossmodal associations. Why does citron smell fast? Can writing outdoors shape our thoughts? Does music curb sweet cravings? We also explore why some sensory associations seem to be missing. For the full exp…
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Brew a cup and join Omar and David for a chat! Today you are joining a conversation I have with David Bean of Nira Skin. In this episode we discuss perhaps one of the greatest most accomplished careers in laser technology. We take a deep dive in understanding his background, how he became inspired by laser technology, the challenges of becoming a s…
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In this episode, I talked with Chris Lowe, CEO of Nusano, where he discusses his career journey in the medical technology field, particularly focusing on the production of medical radioisotopes. He shares insights on leadership, the importance of building a talented team, and the societal responsibilities of his company. Chris also highlights commo…
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In this podcast episode, I talked with Kevin Lynch, co-founder of Populus Bio, where he shares his experience in drug development, particularly in oncology and hematology. He discusses his journey from medicine to the pharmaceutical industry, the cultural insights gained from working globally, and the challenges faced in both personal and professio…
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In this episode, I talked with Victor Paulus, Senior Vice President and Head of Regulatory Affairs at ARTBIO, where he shares his journey in the life sciences industry, discussing his career journey, challenges faced in regulatory affairs, and the unique culture at ARTBIO. He emphasizes the importance of collaboration, mentorship, and understanding…
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In this episode, I talked with Dr. Chris Leamon, Chief Scientific Officer at Fusion Pharmaceuticals, where he shares his journey in the biotech industry, discussing his early influences, the founding of Endocyte, and . He also discusses the challenges faced in drug development, the importance of leadership during workforce reductions, and the lesso…
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In this episode, I talked with Dawn Rubel, President of R&D at NexEos Bio, where she shares her career journey from a scientific technical writer to a leadership role in biotech. She discusses her experiences at Immunomedics, the development of Trodelvy, and her transition to NexEos Bio, where she focuses on eosinophilic inflammation. Dawn emphasiz…
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In this episode, I talked with Orn Almarsson, co-founder of Axelyf, where he shared his journey from Iceland to becoming a prominent figure in the biotechnology industry. He discussed his experiences at Moderna and the development of the mRNA COVID vaccine, Spikevax. He reflects on the challenges faced in drug development, the importance of mentors…
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In this episode, I talked with Dr. Leila Jaffar, CEO of Nuclidium, where she shares her journey from a childhood influenced by her father's passion for science to becoming a leader in the biotech industry. She discusses the challenges she faced during her career, including personal and professional, and her transition from academia to industry. Lei…
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In this episode, I talked with Roger Waltzman, Chief Medical Officer at Indaptus Therapeutics, discussing his career, overview of Indaptus, the development of Indaptus’ lead candidate, and the challenges of cancer treatment. We explore the benefits of a multi-targeted approach in immunotherapy, the story, and the lessons he learned from the failed …
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In this episode of Adventures in Angular, Brad McAlister joins our regular panelists: Alyssa, Chris, and Brooks! Brad walks us through his work of transitioning into an Annex Monorepo and how working with Angular Elements in conjunction has been going. Brad also breaks down what StoryBook is and how it has helped him in his workflows. Picks Alyssa …
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In this episode, I spoke with Gertjan Bartlema, the co-founder Populus Bio and CEO of Immodulon Therapeutics. Over 20 years in big pharma at Celgene/Amgen and then moved into the fast pace world of biotech. From here, he has been challenging the status quo and asking the question “Is our current drug development approaches sustainable?”. Gertjan hi…
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Brew a cup and join Omar and Maximilian for a chat! Today you are joining a conversation I had with Maximilian. He is the Managing Director of Meditrade and founder of GentleCare. In This episode we discuss Maximilian's rich family background in healthcare, how this has impacted his life's direction, his opinions on the importance of work ethic and…
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Michael Hladky joins the adventure to discuss how he's gotten a 60% performance increase using push pipe and related techniques. Many developers can get by without this technology, but Michael explains how to pull the push pipe into your code and what that looks like compared to Zone.js and the default stack in Angular. Links New possibilities with…
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In this episode, I discuss the three most common reasons hiring managers reject candidates, focusing on aspects that are often within the candidate's control. I highlight the importance of cultural fit, alignment of interests, and clarity in communication during interviews. I give tips to improve your interview performance and avoid common pitfalls…
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Joaquin Cid is an Argentinian developer who has built a plugin for NGXS state library that allows developers to connect to Firebase and have their queries automatically import into NGXS. Further, it also allows them to define actions that will update their datastore when triggered. The new Adventures in Angular panel dives into the ins and outs of …
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In today's episode, Lucas is joined by Jason Akbar, a full-stack software engineer who’s got a knack for front-end development. He recently penned some intriguing articles on Medium about RxJS operators. He will reveal what motivated him to write about RxJS operators, especially focusing on the top 17 operators that every Angular developer should k…
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In this episode, I talked with Caroline Vermeulen, Recruitment & HR at Eminence, as she discussed into the details of the hiring process, highlighting the value of putting candidates first. She gave insights on common mistakes in recruiting, the importance of authenticity in communication, and the relationship between hiring managers and recruiters…
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Ankit Sharma, an Angular GDE and author, joins us in this episode of Adventures in Angular to talk about using Azure cognitive services with Angular. Links https://azure.microsoft.com/en-in/services/cognitive-services https://tic-tac-toe-d9068.firebaseapp.com/ https://bookcart.azurewebsites.net/ https://azure.microsoft.com/en-in/services/cognitive-…
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In this episode, I talk about the importance of asking intelligent questions during job interviews. I share insights from my experience coaching candidates, emphasizing how well-structured questions can show enthusiasm, knowledge, and fitness for the role. I cover the types of questions to ask, how to structure them effectively, and the timing to m…
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Armen Vardanyan is an Armenian Angular developer who works extensively with both angular and RXjs. He walks Chuck through the ins and outs of how he uses RXjs to expand the functionality of his Angular applications and how to think about observables in general. Picks Armen- Frank Herbert's Dune Saga 6-Book Boxed Set Charles- The Way of Kings: The S…
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In this episode, I talked with Troels Jordansen, chairman at KELI Therapeutics, where he discusses the ongoing recession in the biotech industry. He shares insights from the Advanced Therapies Congress in Lisbon, highlighting investor optimism and the importance of smart hiring and team building in biotech companies. Troels shares valuable lessons …
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Ravi Veliyat helps train people in many web technologies, Angular being one of them. The panel discusses the various ways you can get your components to communicate, from inputs and outputs all the way up to NgRx. Ravi walks through the different options, with great examples that will keep you on the edge of your headphones. Links You might not nee…
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In this episode, I talked with Sophie, a leader at the Italian pharmaceutical company Bracco, about her experiences and learnings at the Harvard’s negotiation course. Sophie shares her experiences attending the course, highlighting the immersive nature of the program and the diverse backgrounds of participants. We discuss her key takeaways from the…
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Philipp Kief is a German developer who walks through how to manage and capture errors in your Angular application and how to display them to users. He discusses how he standardized error handlers in his applications and what he does to make sure that they get logged someplace. Links Angular Component Extractor Philipp Kief - Medium Philipp Kief Twi…
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In this episode, I talked about a simple yet effective way to ace your interviews by focusing on the three main questions: 'Who are you?', 'Why are you applying?', and 'Why are you looking to leave?'. Learn how to answer these questions in under 2 minutes, how to successfully move on with these three questions, give relevant ABC story, what kind of…
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Nishu Goel joins the Adventure to talk about how Web Components can be used in Angular applications and how to use them to share functionality across multiple applications written in different frameworks. We also dive into how web components are used and compatibility across browsers. Links Angular elements overview manfredsteyer/ngx-build-plus Web…
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In this episode, I interview Nikolaus Trede, the SVP Clinical Development in Century Therapeutics, an innovative biotechnology company that is building an industry leading allogeneic iPSC-derived cell therapy platform. He shares his journey from academia to industry, offering unique experience into the ever-changing world of cell therapies. We also…
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The illustrious and well-regarded Gil Fink joins the Adventures in Angular panel to talk about profiling your Angular apps. Profiling consists of finding bottlenecks, and memory leaks among other problems within your application. Most of the time, the problems are hard to see from the development side. Usually, they appear when your user uses a dev…
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In this episode, Lucas, Armen, and Subrat are joined by Luis Galeas, the CEO and founder of Ambar. Today's discussion dives into the fascinating world of event sourcing, exploring its intricacies in both front-end and back-end development. Event sourcing has emerged as a pivotal technique for managing the state by recording events that can rebuild …
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In this episode of Adventures in Angular, Will Gant, author of Remote Work talks about working from home and working outside of the client's office. He and Brooks share their experience with working through the challenges, benefits, and methods of working remotely. Picks Will - Follow Will's work on > www.simpleprogrammer.com Brooks - NGXS Brooks -…
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Join Michael Bom Frost, from the University of Copenhagen, as he explores the path to sustainable eating. Delve into topics like vertical farming, lab-grown meat, and consumer acceptance of new foods. Discover how blending tradition with innovation can shape a more eco-friendly future. (For comments on social media use #atasteofsustainability.)…
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In this episode of Adventures in Angular the panel interviews Dave Cooper, who recently gave a talk at AngularConnect about using Mock Data. Dave starts by explaining more about his talk and sharing the benefits of using data mocking solutions and rapid prototyping. He shares the secrets of doing rapid prototyping. There are challenges to using moc…
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Freddy Montes joins the adventure to discuss how he and his team manage state in their Angular components. Many development teams instinctively reach for a solution like ngrx when they're building their angular apps and start seeing complex state. However, there's a lot of boilerplate and it's often overkill for small to medium apps. Freddy talks a…
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Have you ever thought how nice it'd be to write your apps for desktop and mobile alongside the web? Richard Sithole joins the adventure to discuss how to pull a desktop app and mobile app into your repo using electron and capacitor to extend the functionality to new platforms. It turns out that a single repo cross-platform app isn't a total pipe dr…
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How do you balance a career in regulatory affairs with family life? In this episode, Charles discusses this topic with Mary Christian, the Senior Vice President of Regulatory and Safety at C4 Therapeutics, a biopharmaceutical company focused on targeted protein degradation. They talk about the importance of effective communication, career developme…
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Dive deep into the latest trends and challenges in the development world. Lucas, Armen, and Subrat Mishra are joined by a special guest, Rakia Ben Sassi, a Google Developer Expert in Angular. In this episode, they explore the complexities and potential benefits of adopting Zoneless Angular and discuss the critical updates in Angular 18, including i…
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Leadership and Diversity in Drug Development with Anita Scheuber. In this episode, Charles talks with Anita Scheuber,the SVP of clinical development at Nimbus Therapeutics—a biotech firm using computational technology to develop medicines. She shares their pioneering work in AI-targeted drug discovery and her experience co-founding the biotech star…
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Special guest, Vitalii Bobrov joins us to talk about accessibility on the web and how to relate it to user experience in general. What can we do to improve accessibility? How can we improve accessibility? Why should we even care about accessibility? Find the answers to these questions and much more on this very insightful episode of Adventures in A…
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In this episode, Charles talks with Jackie Donovan, the VP and Chief Marketing Officer at Syndax Pharmaceuticals, an oncology-focused company. She shares her knowledge about her experiences in consulting, internal pharma roles, and her strategic approach to organizational planning. This conversation also touches on the importance of communication, …
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Alex Eagle is a Software Engineer on the core Angular team at Google. Alex and the panel talk about Bazel, a a free software tool that allows for the automation of building and testing of software. Links Alex’s GitHub Alex’s Twitter Alex’s LinkedIn Bazel Angular and Bazel Join BazelBuild on Slack! Picks Aaron - Axe Throwing Jennifer - Drama on the …
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Hiring Practices and Transparency in Recruitment In this episode, Charles discuss with Patrizio Renzetti, the former Head of HR at Arrakis Therapeutics that discovers RNA-targeted medicines, the importance of cultural fit, psychological safety, and effective communication in the workplace. He also covers the role of recruiters in bringing diverse p…
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