This article delves into objective indicators of brain changes following acupuncture treatment for neurological conditions, particularly stroke, leveraging functional MRI (fMRI) technology. It highlights that scalp acupuncture has shown clinical efficacy, prompting exploration into its underlying brain mechanisms. Various scalp acupuncture protocols are discussed, integrating traditional methods with modern neuroanatomical principles, and Dr. Arthur Yin Fan's concept of "brain-specified acupuncture points" is introduced, noting their tenderness during neurological episodes.

Acupuncture, including scalp acupuncture, has been shown by fMRI to induce significant functional activity changes across multiple brain regions, rather than just areas directly beneath the needle. The World Health Organization recommends acupuncture for stroke, with research suggesting it promotes neurogenesis, regulates cerebral blood flow, and offers anti-inflammatory effects. Meta-analyses using fMRI indicate enhanced brain activity in patients with mild cognitive impairment and activation in language-related areas for aphasia post-stroke. While promising, the article emphasizes the preliminary nature of these findings, calling for larger, multi-center trials to validate the neuroimaging mechanisms of acupuncture.