Adding Perioperative Pembrolizumab To Standard Of Care Improves Outcomes In Patients With Newly Diagnosed Head And Neck Cancers Audio Journal Of Oncology podcast

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Adding Perioperative Pembrolizumab to Standard of Care Improves Outcomes in Patients with Newly Diagnosed Head and Neck Cancers

1d ago 13:26

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Interviews:

Ravindra Uppaluri, MD PhD, Director of Head and Neck Surgical Oncology, Dana Farber Brigham Cancer Center, Boston MA

Ryan B Corcoran MD PhD, Director of the gastrointestinal cancer program, Massachusetts General Hospital Cancer Center, Associate Professor of Medicine Harvard Medical School and Co-Chair of the American Association for Cancer Research Clinical Trials Committee.

CHICAGO, USA—Perioperative immunotherapy, using the PD-1 blocker pembrolizumab both before and after surgery, has been investigated in patients with newly diagnosed head and neck cancers in the phase three KEYNOTE-689 study. Findings were reported at the 2025 Annual Meeting of the American Association for Cancer Research.

Audio Journal of Oncology correspondent Peter Goodwin met up with lead investigator Ravindra Uppaluri MD PhD, Director of Head and Neck Surgical Oncology at the Dana Farber Brigham Cancer Center in Boston MA and Ryan B Corcoran MD PhD, Director of the gastrointestinal cancer program at Massachusetts General Hospital Cancer Center and Co-Chair of the American Association for Cancer Research Clinical Trials Committee.

AACR Abstract Title:

“Neoadjuvant and adjuvant pembrolizumab plus standard of care (SOC) in resectable locally advanced head and neck squamous cell carcinoma (LA HNSCC): Phase 3 KEYNOTE-689 study”

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