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HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
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In this final episode of the Bioenergetics and Brain Health series I talk about changes that occur in brain cells during normal aging, and in Alzheimer’s disease, Parkinson’s disease, and stroke with emphasis on alterations upstream and downstream of cellular energy metabolism. The episode concludes with examples of therapeutic interventions that target those age- and disease-related alterations.
LINKS:
Hallmarks of Brain Aging
https://pmc.ncbi.nlm.nih.gov/articles/PMC6039826/pdf/nihms979409.pdf
Brain Energy Rescue:
https://pmc.ncbi.nlm.nih.gov/articles/PMC7948516/pdf/nihms-1624328.pdf
The Hormesis Principle of Brain Health and Resilience
https://pmc.ncbi.nlm.nih.gov/articles/PMC5209274/pdf/nihms834422.pdf
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