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When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
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Brain tumor cells interact with neurons, glial cells, and immune cells in complex ways that often benefit the cancer cells while compromising the function of normal neural cells. In this episode I talk with Washington University Neurology Professor David Gutmann about brain cancer cells and their communication with surrounding normal cells. A major component of Dr. Gutmann's research program focuses on Neurofibromatosis a rare genetic disorder that causes non-malignant brain tumors as well as abnormal growth of cells in other organ systems. The disease results from loss-of-function mutations in the NF1 protein which normally functions to constrain cell growth. Discoveries concerning the 'sociobiology' of brain tumors is providing a foundation for the development of new approaches for treating a range of cancers.
LINKS
Dr. Gutmann's Wikipedia page: https://en.wikipedia.org/wiki/David_H._Gutmann
Related articles:
https://pmc.ncbi.nlm.nih.gov/articles/PMC10107403/pdf/nihms-1872327.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC9883043/pdf/nihms-1861630.pdf
https://pmc.ncbi.nlm.nih.gov/articles/PMC11972679/pdf/djae249.pdf
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