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HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
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In this episode, we explore the science, history, and frontline application of End-Tidal CO₂ (ETCO₂) — a tool that offers real-time insight into ventilation, perfusion, and metabolism. Danny and Rance from DnR explain how paramedics can use ETCO₂ to assess and guide care across multiple patient presentations.
Key Takeaways:
ETCO₂ is the sixth vital sign — reflecting ventilation, perfusion, and metabolism in real time.
Capnography vs. Oximetry: SpO₂ shows what was happening; ETCO₂ shows what's happening now.
Waveform interpretation: Alpha and beta angles reveal underlying pathology like bronchospasm, obstruction, or air trapping.
Clinical uses:
Tube confirmation: Real-time verification in 6 breaths or less.
CPR: Values
Ventilation: Real-time feedback for rate and volume.
Head injuries: Maintain normocapnia; hyperventilate only during herniation.
Sepsis, trauma, PE, and DKA: Trending ETCO₂ helps identify metabolic and perfusion problems.
Practical tips:
"Filter first, end-tidal to the sky."
Inline sensors outperform sidestream for accuracy.
End-tidal is not just for intubated patients — use it with nasal prongs for sedation and respiratory monitoring.
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