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Dr. Shannon Trotter sits down with Dr. Shawn Kwatra, a leading expert on chronic itch, to shed light on prurigo nodularis (PN)—a painful, often misunderstood condition frequently misdiagnosed as psychological.
Dr. Kwatra explains that PN is driven by a systemic inflammatory cycle between the immune system and nerves, creating an itch patients describe as worse than pain. He shares new insights into diagnosis, mental health impact, and cutting-edge treatments, including two FDA-approved biologics—dupilumab and nemolizumab—that offer real relief.
This episode brings awareness, compassion, and hope to those living with PN—and to the clinicians working to better treat it.
Chapters
1. Introducing Prurigo Nodularis: A Systemic Disease (00:00:00)
2. Meet Dr. Sean Quatra, Expert on Chronic Itch (00:00:56)
3. Clinical Presentation and Misdiagnosis Challenges (00:01:47)
4. The Neuroimmune Axis: How Itch Works (00:05:34)
5. Disease Associations and Diagnostic Workup (00:10:05)
6. Treatment Options: From Topicals to Biologics (00:16:36)
7. Mental Health Impact and Future Treatments (00:22:54)
41 episodes