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Content provided by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://ppacc.player.fm/legal.
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117: Tertiary Lymphoid Structures in Colorectal Cancer Prognosis | Dr. Aleks + AI

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Manage episode 454948454 series 3404634
Content provided by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.

Send us a text

Leveraging AI for Deep Insights into Tertiary Lymphoid Structures in Colorectal Cancer
In this episode of the Digital Pathology Podcast, I introduce 'Aleks + AI,' a new experimental series leveraging Google's Notebook LM to delve deeper into scientific literature.
Today's focus is on tertiary lymphoid structures (TLS) and their potential to predict colorectal cancer prognosis. We discuss a study published in the October 2024 issue of Precision Clinical Medicine, exploring different methods of quantifying TLS using digital pathology and AI.
The paper title is: "Comparative analysis of tertiary lymphoid structures for predicting survival of colorectal cancer: a whole-slide images-based study"
The findings highlight TLS density as a reliable predictor of survival and its correlation with immune responses and microsatellite instability. We also touch upon the potential for AI to streamline TLS analysis in clinical settings and the broader implications for personalized medicine. Join us as we dive into the intersection of digital pathology and computer science, featuring insights and commentary from my AI co-hosts, Hema and Toxy.
00:00 Welcome and Introduction
00:45 Introducing the New AI Tool: Notebook LM by Google
01:11 Experimental Series: "Aleks + AI"
02:06 Deep Dive into Tertiary Lymphoid Structures (TLS)
03:18 Understanding TLS and Their Role in Colorectal Cancer
04:20 Quantification Methods and Key Findings
05:02 Implications for Personalized Medicine
09:02 AI in TLS Analysis and Future Prospects
11:00 CMS Classification and TLS Density
12:08 Study Limitations and Future Directions
15:40 Final Thoughts and Wrap-Up
16:28 Feedback and Future Plans
THIS EPISODE'S RESOURCES

PUBLICATION DISCUSSED TODAY
📝 Comparative analysis of tertiary lymphoid structures for predicting survival of colorectal cancer: a whole-slide images-based study
🔗https://academic.oup.com/pcm/article/7/4/pbae030/7826772

📱 Send us a text

Support the show

Become a Digital Pathology Trailblazer get the "Digital Pathology 101" FREE E-book and join us!

  continue reading

137 episodes

Artwork
iconShare
 
Manage episode 454948454 series 3404634
Content provided by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Aleksandra Zuraw, DVM, PhD, Aleksandra Zuraw, and DVM or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.

Send us a text

Leveraging AI for Deep Insights into Tertiary Lymphoid Structures in Colorectal Cancer
In this episode of the Digital Pathology Podcast, I introduce 'Aleks + AI,' a new experimental series leveraging Google's Notebook LM to delve deeper into scientific literature.
Today's focus is on tertiary lymphoid structures (TLS) and their potential to predict colorectal cancer prognosis. We discuss a study published in the October 2024 issue of Precision Clinical Medicine, exploring different methods of quantifying TLS using digital pathology and AI.
The paper title is: "Comparative analysis of tertiary lymphoid structures for predicting survival of colorectal cancer: a whole-slide images-based study"
The findings highlight TLS density as a reliable predictor of survival and its correlation with immune responses and microsatellite instability. We also touch upon the potential for AI to streamline TLS analysis in clinical settings and the broader implications for personalized medicine. Join us as we dive into the intersection of digital pathology and computer science, featuring insights and commentary from my AI co-hosts, Hema and Toxy.
00:00 Welcome and Introduction
00:45 Introducing the New AI Tool: Notebook LM by Google
01:11 Experimental Series: "Aleks + AI"
02:06 Deep Dive into Tertiary Lymphoid Structures (TLS)
03:18 Understanding TLS and Their Role in Colorectal Cancer
04:20 Quantification Methods and Key Findings
05:02 Implications for Personalized Medicine
09:02 AI in TLS Analysis and Future Prospects
11:00 CMS Classification and TLS Density
12:08 Study Limitations and Future Directions
15:40 Final Thoughts and Wrap-Up
16:28 Feedback and Future Plans
THIS EPISODE'S RESOURCES

PUBLICATION DISCUSSED TODAY
📝 Comparative analysis of tertiary lymphoid structures for predicting survival of colorectal cancer: a whole-slide images-based study
🔗https://academic.oup.com/pcm/article/7/4/pbae030/7826772

📱 Send us a text

Support the show

Become a Digital Pathology Trailblazer get the "Digital Pathology 101" FREE E-book and join us!

  continue reading

137 episodes

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