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When you hear the words Alzheimer's disease, what do you think of? The truth is, the picture most of us have of the disease is incomplete. Alzheimer's disease doesn't start when someone starts to lose their memory. It actually starts years – sometimes decades – earlier. The Rethinking Alzheimer's Disease Podcast is an engaging, narrative-style podcast miniseries for those curious or motivated to learn about Alzheimer’s disease. Perhaps you have a family member with Alzheimer’s disease, or ca ...
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🔍 Two influential viewpoints just dropped in JAMA Cardiology on aortic valve replacement (AVR) in asymptomatic severe aortic stenosis (AS).
🫀 Lindman, Braunwald & Pellikka argue that the time has come to move from “watchful waiting” to early intervention (SAVR/TAVR), citing RCTs showing reduced stroke, heart failure hospitalization, and unplanned CV events.
⚖️ Hillis, McCann & Newby counter that the evidence is not yet strong enough for a universal shift—pointing to trial limitations, competing risks in older patients, and the danger of unnecessary procedures.
✨ The debate is clear: Act early or wait carefully?
This conversation is shaping the future of valve guidelines and clinical practice.
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