Dr. Chase Spears reunites with his former Georgetown professor, award-winning speechwriter, and bestselling author Mike Long (The Molecule of More, Taming the Molecule of More) for a wide-ranging conversation on dopamine—the brain chemical that drives ambition, restlessness, and the endless chase for “more.”

They explore why dopamine isn’t the “happiness molecule” at all, how it fuels both human progress and modern dissatisfaction, why true meaning (not comfort) is the only lasting antidote to perpetual wanting, and how understanding this one neurotransmitter can give you the courage to stand firm when everything around you screams “compromise.” A masterclass in brain science, character, and living with spine in a world engineered to hijack your attention.

00:00:00 - Introduction

00:03:41 - Mike’s Books & Dopamine 101

00:09:49 - What Dopamine Really Is

00:14:33 - Perpetual Dissatisfaction

00:18:37 - Finding Meaning That Satisfies

00:23:33 - Comfort vs. Conscience

00:26:07 - Ancient Survival Tool Gone Wild

00:43:18 - Courage to Face Who You Really Are

00:54:26 - Living in a Polarized Society

01:00:48 - Choosing Virtues That Anchor You

01:11:38 - Enjoy Every Sandwich

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