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For as long as humans have walked this Earth, we have been using chemicals to alter our state of mind. Drugs and alcohol have been used in rituals and medication, for inspiration and escapism, as well as a way to cope with the world. Only in more recent decades have we begun to appreciate the physiological effects that substances have on our brains through science. Host Dr Alfredo Carpineti spoke to neuropsychopharmacologist Professor David Nutt about these effects and a new approach to manufacturing alcohol without the negative consequences.

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