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NASA and JAXA data show space-grown crops look healthy but are mineral-deficient—calcium drops about 29–31% and magnesium ~25% versus Earth-grown crops—raising bone, immune, and kidney risks for astronauts. In this deep dive, we explore the space food paradox, the potential of bioengineered 'food as medicine' (like PTH-producing lettuce) and biofortified crops, and the challenge of creating a closed-loop life-support system that keeps food nutritious for years. We also discuss storage longevity and what it would take to feed a multi-year mission—lessons that could reshape Earthly food security as well.

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