Share
))
HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
…
continue reading
Manage episode 474432574 series 3555208
Content provided by MedEvidence Articles. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by MedEvidence Articles or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
This podcast explores Limbic-predominant Amnestic Neurodegenerative Syndrome (LANS), a newly identified condition that primarily affects episodic memory while leaving other cognitive functions relatively intact. LANS is associated with the misfolding of TDP-43, a protein that can accumulate and damage limbic structures. Unlike Alzheimer’s, LANS has a slower onset and lacks definitive diagnostic tests, making research critical for future treatments. With the aging population, understanding and addressing LANS could become as significant as Alzheimer’s research.
Share with a friend. Rate, Review, and Subscribe to MedEvidence! Articles to be notified when new episodes are released.
Follow us on Social Media:
Facebook
Instagram
Twitter
LinkedIn
Tiktok
Youtube
For more great content, including discussions by physicians and clinical research experts, check out the MedEvidence! podcast. www.MedEvidence.com
Thank you for listening!
References:
Morgane, P. J., et al. (2005). A review of systems and networks of the limbic forebrain/limbic midbrain. Progress in neurobiology, 75(2), 143-160. https://www.sciencedirect.com/science/article/pii/S030100820500002X
Catani, M., et al. (2013). A revised limbic system model for memory, emotion and behaviour. Neuroscience & Biobehavioral Reviews, 37(8), 1724-1737. https://www.sciencedirect.com/science/article/pii/S0149763413001711
Knopman, D. S., et al. (2021). Alzheimer disease. Nature reviews Disease primers, 7(1), 33. https://www.nature.com/articles/s41572-021-00269-y
Corriveau-Lecavalier, N., et al. (2024). Clinical criteria for a limbic-predominant amnestic neurodegenerative syndrome. Brain Communications, 6(4). https://academic.oup.com/braincomms/article/6/4/fcae183/7712717
Wolk, D. A., et al. (2024). Clinical criteria for Limbic‐Predominant age‐related TDP‐43 encephalopathy. Alzheimer's & Dementia, e14202. https://alz-journals.onlinelibrary.wiley.com/doi/pdf/10.1002/alz.14202
Nelson, P. T., et al. (2019). Limbic-predominant age-related TDP-43 encephalopathy (LATE): consensus working group report. Brain, 142(6), 1503-1527. https://academic.oup.com/brain/article/142/6/1503/5481202
Tremblay, C., et al. (2011). Accumulation of transactive response DNA binding protein 43 in mild cognitive impairment and Alzheimer disease. Journal of Neuropathology & Experimental Neurology, 70(9), 788-798. https://pmc.ncbi.nlm.nih.gov/articles/PMC3197017/
Mackenzie, I. R., et al. (2011). A harmonized classification system for FTLD-TDP pathology. Acta neuropathologica, 122, 111-113. https://pmc.ncbi.nlm.nih.gov/articles/PMC3285143/
85 episodes
