In this episode we cover:

The documentaries:

CNCBC Big Shot : The Ozempic Revolution

And

Impact X Nightline Season 2, Episode 20, The Skinny Confessions: After Ozempic

The movie, “Faces in the Crowd”

And

The book, “Hello Stranger” by Katherine Center

Sources:

Obesity

https://obesitymedicine.org/blog/why-is-obesity-a-disease/

https://pmc.ncbi.nlm.nih.gov/articles/PMC6179496/

https://www.ajmc.com/view/review-of-current-guidelines-for-the-treatment-of-obesity

GLP-1 Agonists

https://pubmed.ncbi.nlm.nih.gov/26371721/

https://www.biochempeg.com/article/299.html#:~:text=In%202005%2C%20Exendin%2D4%20(Exenatide/%20BYETTA)%2C%20the%20world's,diabetes%20with%20two%20injections%20per%20day%20(BID).

https://pmc.ncbi.nlm.nih.gov/articles/PMC7042958/#:~:text=The%20first%20GLP%2D1%20receptor,weight%20loss%2C%20low%20risk%20for

https://www.ncbi.nlm.nih.gov/books/NBK572151/#:~:text=The%20FDA%20approved%20the%20first,than%20safety%20or%20efficacy%20concerns.

https://pmc.ncbi.nlm.nih.gov/articles/PMC6946151/#:~:text=Members%20of%20the%20SGLT2i%20class,cardiovascular%20death%20or%20heart%20failure

Wegovy:

https://www.wegovy.com/

Zepbound:

https://zepbound.lilly.com/

Ozempic:

https://www.ozempic.com/why-ozempic/what-is-ozempic.html?showisi=true&&utm_source=google&utm_medium=cpc&utm_term=ozempic&utm_campaign=1_All_Shared_BR_Branded_Specifics_2023&mkwid=s-dc_pcrid_677045568899_pkw_ozempic_pmt_e_slid__product_&pgrid=158457129350&ptaid=kwd-392229870365&gad_source=1&gclid=Cj0KCQiAoJC-BhCSARIsAPhdfSgsOVJxGYMUGpDLJloXHBglxtpzF30jZ1ZIrHVfAaXMJ6pVL5aeeoQaAuorEALw_wcB&gclsrc=aw.ds

Mounjaro:

https://mounjaro.lilly.com/savings-resources?utm_id=go_cmp-20975809605_adg-158741897736_ad-715583170976_kwd-1655589599942_dev-c_ext-_prd-_mca-_sig-Cj0KCQiAoJC-BhCSARIsAPhdfSjZp4RyQOf_BRnYqOzDv2_XWbnelsvu73fwWdiTLe1TF1OUP60taK4aApMtEALw_wcB&utm_source=google&utm_medium=ppc&campaign=20975809605&adgroup=158741897736&ad=715583170976&utm_keyword=kwd-1655589599942&utm_term=go_cmp-20975809605_adg-158741897736_ad-715583170976_kwd-1655589599942_dev-c_ext-_prd-_mca-_sig-Cj0KCQiAoJC-BhCSARIsAPhdfSjZp4RyQOf_BRnYqOzDv2_XWbnelsvu73fwWdiTLe1TF1OUP60taK4aApMtEALw_wcB&utm_rand=18243860566256925089&gad_source=1&gclid=Cj0KCQiAoJC-BhCSARIsAPhdfSjZp4RyQOf_BRnYqOzDv2_XWbnelsvu73fwWdiTLe1TF1OUP60taK4aApMtEALw_wcB

Future possible indications

https://www.aasld.org/liver-fellow-network/core-series/why-series/why-are-glp-1-agonists-being-used-treat-patients

https://www.biospace.com/drug-development/evidence-mounts-for-potential-of-glp-1s-in-alzheimers-disease

https://www.sciencedirect.com/science/article/pii/S1043661824002573#:~:text=4.2.-,Clinical%20evidence,RCT%20in%20individuals%20with%20OUD.

Psych uses: https://www.psychologytoday.com/us/blog/happy-healthy-relationships/202312/can-semaglutide-treat-obesity-diabetes-and-mental-health

Cocktail:

https://www.absolutdrinks.com/en/drinks/skinny-bitch/

Prosopagnosia

Faker Face Cocktail - https://www.mixelcocktails.com/r/faker_face38311/

Faces in the Crowd movie https://en.wikipedia.org/wiki/Faces_in_the_Crowd_(2011_film)

2011, starring Milla Jovovich, crime thriller - Anna acquires prosopagnosia after a TBI after witnessing a crime; makes it difficult to ID the killer; shows emotional/social difficulties; beautiful portrayal using several different actors to play each character - as a movie not great

Hello Stranger by Katherine Center - Sadie has a seizure caused by cavernoma and has surgery then develops prosopagnosia - leads to a meet cute gone sideways and difficulty with her goal of being a portrait artist https://www.goodreads.com/book/show/61884987-hello-stranger

https://en.wikipedia.org/wiki/Brilliant_Minds Brilliant Minds - Oliver Wolf - https://www.oliversacks.com/watch-listen/brilliant-minds/

Types of agnosia - brain does not process senses appropriately - specific to facial recognition - usually from injury/lesions (alzheimers/dementia, tumors, TBI, developmental disorders, hypoxia, seizure/epilepsy, stroke, carbon monoxide poisoning), can be from birth/possible genetic link

Expressions/nonverbals - apperceptive type

Face blindness - associative

Dx via imaging and diagnostic tests

Shame, anxiety, embarrassment, affects social relationships

Tx - treat underlying disorder, if any; coping skills, perceptual training

Treatment

• Treatment focuses on helping the person adapt to recognize people in other ways

Coping mechanisms can include teaching the person to study and remember other features, such as hair color, height, and voice

Notable people with prosopagnosia

• Jane Goodall, primatologist
• Brad Pitt, actor
• Steve Wozniak, Apple co-founder

Stats vary but around 3% of the population

https://my.clevelandclinic.org/health/diseases/23412-prosopagnosia-face-blindness

https://hms.harvard.edu/news/how-common-face-blindness

https://www.faceblind.org/research/

https://www.testmybrain.org/#Digital-Lab

https://pmc.ncbi.nlm.nih.gov/articles/PMC10901275/

Music Credits:

Intro fun- Music by Vlad Krotov from Pixabay

Bartending foley suite- Sound Effect by Akiva Vita from Pixabay

Website:

https://medicalmediamixer.podbean.com/

Social Media Links:

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Email:

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