Henry King and Vala Afshar, co-authors of Autonomous, join me to explore how AI-first strategies are reshaping business fitness. Henry brings his unique journey from CIO to design thinking expert, whilst Vala shares insights from his decade as Salesforce's chief evangelist. We examine Salesforce's V2MOM framework—a radical transparency tool that aligns 80,000 employees—and discuss why the best implementations often mean resisting customisation. The conversation tackles uncomfortable truths about autonomous vehicles, digital labour, and the erosion of human agency, whilst exploring how companies can eliminate waste through agentic AI. Henry and Vala challenge the notion that relationships will diminish in an AI-driven world, arguing instead that they'll become more critical. We discuss enterprise fitness, the importance of identifying organisational blockages, and why trust—defined as competence plus character—remains the foundation for transformation in an age where we're the last generation managing only people.