In the very first episode of the Nick Strong Podcast, hosts Matt Medeiros and Jen McCabe speak with Dr. Joanna Gell, a physician-scientist at The Jackson Laboratory for Genomic Medicine and Connecticut Children’s. Dr. Gell shares an accessible and heartfelt look at her groundbreaking research into germ cell tumors, including those found in the brain, and explains how scientific progress connects directly to the lives of children and families affected by pediatric cancer.

Through this conversation, listeners learn how translational research — the bridge between lab discoveries and clinical care — can lead to better diagnostics, improved treatments, and reduced long-term side effects for young patients. Dr. Gell also discusses the unique challenges of studying rare cancers, the importance of community-driven funding, and how even modest donations can fuel life-changing breakthroughs.

Jen reflects on her son Nick’s experience with a rare intracranial germ cell tumor, underscoring why awareness, research, and parent support networks are so critical. Together, they remind listeners that hope, collaboration, and persistence are at the heart of every medical advancement.

Key Takeaways

• Translational research connects lab discoveries (in mice and cell models) to real-world treatments for children.
• Germ cell tumors originate from reproductive cells and can appear in unexpected areas, like the brain.
• Rarity makes research difficult, but focused funding and collaboration can drive vital progress.
• Liquid biopsy techniques may allow doctors to diagnose and monitor brain tumors less invasively.
• Every contribution counts — even small donations help launch projects that can evolve into major breakthroughs.

Important Links & Resources

• The Jackson Laboratory
• Connecticut Children’s Medical Center
• Nick Strong Foundation
• Help and Hope Happens Here Podcast