In this episode, we talk with Kayo Yin, an incoming PhD at Berkeley, and Malihe Alikhani, an assistant professor at the University of Pittsburgh, about opportunities for the NLP community to contribute to Sign Language Processing (SLP). We talked about history and misconceptions about sign languages, high-level similarities and differences between spoken and sign languages, distinct linguistic features of signed languages, representations, computational resources, SLP tasks, and suggestions for better design and implementation of SLP models.