In this milestone 333rd episode of The Stag Roar Podcast, Professor Grant Schofield returns for a third appearance to dive into the science and mindset behind fasting, metabolic health, and disease prevention. Host Ryan reflects on their previous episodes and revisits key topics with fresh insights-from macular degeneration and mitochondrial health to diabetes and the role of autophagy. Grant shares why he and Louise Schofield commit to an annual five-day fast, the discipline required to do hard things, and how lifestyle choices can radically influence long-term wellbeing. He also teases his upcoming book, centred on the power of discomfort as a path to health.