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Aspartate transaminase

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Manage episode 480464630 series 3433497
Content provided by Abulsme Productions. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Abulsme Productions or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
rWotD Episode 2922: Aspartate transaminase
Welcome to Random Wiki of the Day, your journey through Wikipedia's vast and varied content, one random article at a time.
The random article for Sunday, 4 May 2025, is Aspartate transaminase.
Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954. AST catalyzes the reversible transfer of an α-amino group between aspartate and glutamate and, as such, is an important enzyme in amino acid metabolism. AST is found in the liver, heart, skeletal muscle, kidneys, brain, red blood cells and gall bladder. Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels.
The half-life of total AST in the circulation approximates 17 hours and, on average, 87 hours for mitochondrial AST. Aminotransferase is cleared by sinusoidal cells in the liver.
This recording reflects the Wikipedia text as of 00:09 UTC on Sunday, 4 May 2025.
For the full current version of the article, see Aspartate transaminase on Wikipedia.
This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.
Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.
Follow us on Mastodon at @[email protected].
Also check out Curmudgeon's Corner, a current events podcast.
Until next time, I'm neural Joey.
  continue reading

100 episodes

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Aspartate transaminase

random Wiki of the Day

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Manage episode 480464630 series 3433497
Content provided by Abulsme Productions. All podcast content including episodes, graphics, and podcast descriptions are uploaded and provided directly by Abulsme Productions or their podcast platform partner. If you believe someone is using your copyrighted work without your permission, you can follow the process outlined here https://staging.podcastplayer.com/legal.
rWotD Episode 2922: Aspartate transaminase
Welcome to Random Wiki of the Day, your journey through Wikipedia's vast and varied content, one random article at a time.
The random article for Sunday, 4 May 2025, is Aspartate transaminase.
Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a pyridoxal phosphate (PLP)-dependent transaminase enzyme (EC 2.6.1.1) that was first described by Arthur Karmen and colleagues in 1954. AST catalyzes the reversible transfer of an α-amino group between aspartate and glutamate and, as such, is an important enzyme in amino acid metabolism. AST is found in the liver, heart, skeletal muscle, kidneys, brain, red blood cells and gall bladder. Serum AST level, serum ALT (alanine transaminase) level, and their ratio (AST/ALT ratio) are commonly measured clinically as biomarkers for liver health. The tests are part of blood panels.
The half-life of total AST in the circulation approximates 17 hours and, on average, 87 hours for mitochondrial AST. Aminotransferase is cleared by sinusoidal cells in the liver.
This recording reflects the Wikipedia text as of 00:09 UTC on Sunday, 4 May 2025.
For the full current version of the article, see Aspartate transaminase on Wikipedia.
This podcast uses content from Wikipedia under the Creative Commons Attribution-ShareAlike License.
Visit our archives at wikioftheday.com and subscribe to stay updated on new episodes.
Follow us on Mastodon at @[email protected].
Also check out Curmudgeon's Corner, a current events podcast.
Until next time, I'm neural Joey.
  continue reading

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