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HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
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*For the BEST visual experience, I highly suggest watching this podcast episode on YouTube here.*
In this episode I do my best to break down and to simplify the cellular processes that result in abnormal aggregation of the protein alpha-synuclein in the nerve cells that produce #dopamine and how this leads to most of, if not all of, the problems caused by PD. In this video I reference this paper regarding the endo-lysosomal (E-L) pathway in cells, genetic links to PD, and how alpha-synuclein aggregates and what issues this causes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707858/
Please please consider reading this amazing book by Dr. Christopher Palmer, MD on the role of mitochondria in neurological diseases like PD! It is a MUST read: https://amzn.to/49eNbZs
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Medical Disclaimer: All information, content, and material of this video is for informational purposes only and not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider.
Affiliate disclaimer: Keep in mind that links used for recommended products may earn me a commission when you make purchases. However, this does not impact what products I recommend. If I recommend a specific product it is because it has been vetted by myself or based on personal use.
#parkinson #parkinsonsawareness #parkinsonsdisease #parkinsons #neuroscience #cellbiology #education
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