Episode Overview

Join Kristen Parise as she sits down with Jessica Caceres, a nurse practitioner with 15 years of experience who's revolutionizing women's hormonal health care. From frustrating dismissals in traditional medicine to pioneering a holistic approach to hormone therapy, Jessica shares her journey and expert insights on navigating the often turbulent waters of perimenopause and menopause.

What You'll Learn

• Why the infamous Women's Health Initiative study created decades of fear—and why much of it was unfounded
• The critical differences between synthetic and bioidentical hormones
• How to recognize when your body is entering the "zone of chaos" known as perimenopause
• Why joint pain might be your first clue that hormonal changes are happening
• The life-changing (and potentially life-saving) benefits of vaginal estrogen
• When to seek help for hormonal changes and what to expect

Episode Highlights Jessica's Transformation from Traditional Medicine to Hormone Hero

Jessica describes her awakening to the gaps in women's healthcare after years in family medicine, where she noticed women's hormonal concerns being consistently dismissed or treated with band-aid solutions like antidepressants. Her own frustration with her inability to truly help these patients led her to extensive training in functional medicine and hormone optimization, completely transforming her approach to patient care.

The Women's Health Initiative: Setting the Record Straight

Learn why this 20-year-old study created widespread fear around hormone replacement therapy despite major flaws in methodology. Jessica breaks down how the study used women who were too old, synthetic hormones instead of bioidentical ones, and oral medications instead of safer topical options—all leading to misleading conclusions that have impacted millions of women's health decisions.

The Perimenopausal Roller Coaster: What to Expect When Everything's Unexpected

Jessica vividly describes perimenopause as a "treacherous valley" of hormonal peaks and troughs, explaining why symptoms can vary so wildly and change so quickly. From heavy periods to joint pain, brain fog to sleep disturbances, she offers clear guidance on recognizing the signs and knowing when to seek help.

Beyond Hot Flashes: The Musculoskeletal Syndrome of Menopause

Discover the surprising connection between estrogen decline and joint pain, frozen shoulder, back pain, and other musculoskeletal issues. Jessica and Kristen discuss how these symptoms are often overlooked despite being some of the earliest and most common complaints among perimenopausal women.

"Vaginal Estrogen Saves Lives": Breaking the Taboo

In perhaps the most powerful segment of the conversation, Jessica passionately advocates for vaginal estrogen as a game-changing treatment that's safe for everyone—even breast cancer survivors. She shares moving stories of women in their 70s, 80s, and 90s whose lives were transformed by this simple intervention, and why breaking the stigma around discussing vaginal health is literally a matter of life and death.

Episode Chapters

• 00:00-08:00: Introduction to Hormonal Health and Jessica's Journey – From family medicine to women's hormone specialist
• 08:01-19:18: The Shift in Women's Health Perspectives – How outdated studies created fear and confusion
• 19:19-25:27: Understanding Perimenopause and Hormone Replacement Therapy – The basics of bioidentical hormones
• 25:28-28:28: Addressing Heavy Periods and Hormonal Changes – More than just "take some iron"
• 28:29-31:55: Understanding Perimenopause Symptoms – From hot flashes to brain fog and beyond
• 31:56-35:03: The Chaos of Hormonal Changes – Navigating the unpredictable "zone of chaos"
• 35:04-37:24: Hormone Replacement Therapy: Lifelong Considerations – Is it forever? (Spoiler: it can be!)
• 37:25-40:56: The Importance of Vaginal Estrogen – A passionate case for this life-changing treatment
• 40:57-46:40: Breaking the Stigma Around Women's Health Conversations – Educating ourselves and future generations

Connect with Jessica

• Website: Bonita Medical Aesthetics and Wellness
• Instagram: @youare.bonita
• Email: [email protected]
• Location: New facility in St. Jacob's

Connect with The Hole Shebang

• Website: Blueberry Therapy Pelvic Health and Pediatrics
• Instagram: @blueberrytherapypelvichealth
• Upcoming Event: The Pleasure Principle

Jessica's Theme Song for Her Career

"Still Standing" by Elton John – perfectly capturing her journey through clinical practice and commercial renovation!