Ariel Helwani begins the show by recapping the massive UFC 324 and UFC 325 announcements, including reaction from fighters involved in the fights or fighters passed up for title opportunities (05:25).

Joshua Van stops by during UFC 323 fight week to preview his matchup with Alexandre Pantoja, talk about his calmness before the storm and his longer-than-average layoff, react to Kyoji Horiguchi’s return and callout, and more (26:21).

WBA super featherweight champion Lamont Roach joins Ariel in-studio ahead of his super lightweight scrap with Isaac 'Pitbull' Cruz to discuss his rivalry with Gervonta ‘Tank’ Davis and a potential rematch, appealing the result of their first fight, whether he believes Davis is retired, his perspective on the Ali Revival Act, and more (46:40).

Ariel addresses recent comments by Kamaru Usman and Henry Cejduo (1:16:50), before reuniting with old friend Tony Ferguson, who reflects on his win over Salt Papi in August, previews his return against Warren Spencer in December, discusses his relationship with Dillon Danis, his views on UFC’s recent matchmaking, planning to fight MMA again, his prediction for Paddy Pimblett vs. Justin Gaethje, and more (1:34:55).

Lerone Murphy is back to react to the announcement of Alexander Volkanovski vs. Diego Lopes 2, express his disappointment with not getting the title shot and potentially missing out on fighting Volkanovski before he retires, answer the callouts of Movsar Evloev and Aljamain Sterling, give his prediction for the Volkanovski-Lopes rematch, and more (2:04:16).

UFC women’s bantamweight champion Kayla Harrison returns to break down her highly-anticipated fight against Amanda Nunes, reveal a bit about their time as training partners, react to Ronda Rousey’s rumored comeback and potential boxing match with Katie Taylor, respond to Valentina Shevchenko’s callout, and more (2:26:04).

Ariel and The Boys in the Back wrap up with some news and notes, including the latest on Tom Aspinall’s eye, and answer your Super Chats (3:08:30).