Abstract: Organizations adopting artificial intelligence face a fundamental structural challenge: traditional hierarchies and coordination mechanisms often stifle the experimentation and rapid iteration AI implementation requires. Emerging evidence suggests that small, cross-functional teams with high autonomy—typically comprising senior engineers, domain experts, and experienced product managers—deliver faster time-to-value and stronger early returns on AI investments than centralized, top-down approaches. This article examines the organizational design principles enabling these teams to succeed and addresses the critical gap in enterprise-scale coordination mechanisms. Drawing on organizational theory, agility research, and practitioner accounts from technology, financial services, and healthcare sectors, we propose a dual-operating system model that preserves the benefits of autonomous pods while building connective tissue for resource allocation, knowledge sharing, and strategic alignment. The article concludes with evidence-based recommendations for leaders navigating the transition from experimental AI initiatives to institution-wide capability.