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Paper: Scaling Large Language Models for Next-Generation Single-Cell Analysis by Rizvi et al

Paper link: https://www.biorxiv.org/content/10.1101/2025.04.14.648850v2

This week we're covering recent research presenting C2S-Scale, a new model from researchers at Yale and Google that teaches Large Language Models the "language of the cell."

By translating complex genomic data into "cell sentences," this AI can predict cellular behaviour, answer complex biological questions, and has even made a novel, lab-validated discovery that could enhance cancer immunotherapy.

But what's the real hurdle between this incredible research tool and real-world clinical impact? We break down the ambition, the obstacles, and the concrete steps needed to build clinical trust in arguably one of the most exciting developments in Health AI this year.

#HealthAI #ArtificialIntelligence #Genomics #SingleCell #DrugDiscovery #LLM #BioTech #DigitalHealth #MedicalInnovation #C2SScale #ai in medicine Music generated by Mubert https://mubert.com/render

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