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HBO and The Ringer's Bill Simmons hosts the most downloaded sports podcast of all time, with a rotating crew of celebrities, athletes, and media staples, as well as mainstays like Cousin Sal, Joe House, and a slew of other friends and family members who always happen to be suspiciously available.
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What if evolution is not a finished act, but an ongoing collaboration between ancestry and awareness?
In this interlude of The Observable Unknown, Dr. Juan Carlos Rey of crowscupboard.com explores the profound intersection between phylogenetic inertia - the evolutionary gravity that preserves our biological past - and epigenetic rewriting, the molecular poetry of adaptation that lets life edit its own script.
Through studies by Dr. Samuel Almeida, Dr. Michael Kertes, Dr. Jessica Loke, Dr. Steve Horvath, and Dr. Helena Verdile, this episode reveals how inheritance moves beyond genes: into chemistry, emotion, opportunity, and choice.
From prenatal stress shaping neural architecture to trauma accelerating biological age, Interlude XV examines how the genome is less a fixed code and more a living text - revised through experience, reflection, and resilience.
The question at its center is timeless:
If life remembers itself through us, what might we, in turn, choose to remember for it?
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