In this continuation of our deep dive into government-funded clinical trials, we explore real-world examples of how these studies operate differently from private pharma-sponsored research. Our guest shares firsthand insights into challenges like proving adverse events without medical records, navigating patient compensation differences, and the disconnect between research benchmarks and real-life feasibility. We also discuss the impact of wealth distribution on patient access and trial participation. What happens when hospitals close patient accounts, but research teams still need documentation? How do these trials ensure continuity of care? Join us as we unpack the complexities of conducting research in a government-funded setting.