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The observed variety of dendritic structures in the brains is striking. Why are they so different, and what determine the branching patterns?

Following the dictum “if you understand it, you can build it”, the lab of the guest builds dendritic structures in a computer and explore the underlying principles.

Two key principles seem to be to minimize (i) the overall length of dendrites and (ii) the path length from the synapses to the soma.

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